Stereotactic Body Radiation Therapy

Stereotactic Body Radiation Therapy

by Brian D. Kavanagh
     
 

ISBN-10: 0781754208

ISBN-13: 9780781754200

Pub. Date: 09/27/2004

Publisher: Lippincott Williams & Wilkins

This text provides oncology professionals with a practical understanding of the basic science, technical aspects, and clinical indications of stereotactic body radiation therapy, including radiosurgery, radiotherapy, and radioablation. Coverage includes discussions of relevant classical and molecular radiobiological principles, critical evaluations of currently

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Overview

This text provides oncology professionals with a practical understanding of the basic science, technical aspects, and clinical indications of stereotactic body radiation therapy, including radiosurgery, radiotherapy, and radioablation. Coverage includes discussions of relevant classical and molecular radiobiological principles, critical evaluations of currently used techniques, and background clinical oncology information plus summaries of reported outcomes for patients treated in the lung, liver, and spine.

Product Details

ISBN-13:
9780781754200
Publisher:
Lippincott Williams & Wilkins
Publication date:
09/27/2004
Pages:
160
Product dimensions:
8.60(w) x 11.20(h) x 0.50(d)

Table of Contents

Prologue : the clinical transition from intracranial to extracranial stereotactic radiation therapy1
Sect. IThe radiobiology of stereotactic body radiation therapy (SBRT)7
1Estimation of required doses in stereotactic body radiation therapy7
2The cellular signaling response to radiation15
3Radiation effects and the role of cytokines : mechanisms and potential clinical implications19
4Normal tissue dose constraints applied in lung stereotactic body radiation therapy29
5Normal tissue dose constraints in stereotactic body radiation therapy for liver tumors39
6Special problems in stereotactic body radiation therapy : dose rate effect, dose inhomogeneity, and target margin selection47
Sect. IIThe physics and dosimetry of stereotactic body radiation therapy51
7Immobilization, localization, and repositioning methods in stereotactic body radiation therapy51
8Dosimetry of stereotactic body radiation therapy57
9Quality assurance in stereotactic body radiation therapy69
Sect. IIIInitiating and building a clinical stereotactic body radiation therapy program79
10Clinical operational issues : optimizing the treatment process79
11Commissioning and accreditation of a stereotactic body radiation therapy program85
12Personnel training for stereotactic body radiation therapy95
13Stereotactic body radiation therapy for lung tumors99
Case studies in lung SBRT : application of the FOCAL unit108
Case study in lung SBRT : the Indiana University phase II protocol for medically inoperable lung cancer110
Case study in lung SBRT : long-term follow-up in a patient with a history of tuberculosis
14Stereotactic body radiation therapy for liver tumors115
Case study in liver SBRT : dose optimization via inverse treatment planning125
15Stereotactic body radiation therapy for renal cell carcinoma129
16Stereotactic body radiation therapy for retroperitoneal and pelvic tumors135
Case study in prostate SBRT : the SHARP protocol140
17Stereotactic body radiation therapy for paraspinal tumors143
Case study of spinal SBRT : radiosurgery for vertebral metastasis150

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