Stockley's Drug Interactions / Edition 8

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More About This Textbook

Overview

Stockley's Drug Interactions, edited by Karen Baxter, remains the world's most comprehensive and authoritative reference book on drug interactions.
• Contains detailed yet concise monographs
• Covers interactions between therapeutic drugs, proprietary medicines, herbal medicines, foods, drinks, pesticides and drugs of abuse
• Based on published sources and fully referenced
• Provides comprehensive details of the clinical evidence for the interactions under discussion, an assessment of their clinical importance and gives clear guidance on how to manage the interaction in practice
• Contains over 3,400 monographs New for the 9th edition:
• Over 300 new monographs
• All monographs fully revised and revalidated
• Three new chapters on the interactions of Thyroid Hormones, Urological drugs, and Nutritional agents, Supplements and Vitamins
• New drugs launched in the last two years added - including drugs such as fesoterodine, several monoclonal antibodies, new antidiabetics (e.g. sitagliptin) new antineoplastics (e.g. dasatinib) and new immunosuppressants (e.g. temsirolimus)
• Updated information on seasonal flu vaccines and antivirals, including all available information on possible interactions with concurrent medication
• Increased commentary on the involvement of newer mechanisms in drug interactions, such as drug transporter proteins, and other genetic factors that affect the ability of individuals to metabolise medicines
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Editorial Reviews

Doody's Review Service
Reviewer: Jill Suzanne Bates, PharmD, MS (University of North Carolina Hospitals)
Description: This is a comprehensive tertiary reference that compiles monographs describing well-documented drug interactions. The previous edition was published in 2008.
Purpose: The aim is to provide healthcare professionals important information about drug interactions so they don't have to do the time-consuming literature searches and full assessment of the papers themselves. This is a very comprehensive compilation of information on drug interactions without subjective ratings, thereby letting readers place their own value on the information.
Audience: The book is written with practitioners in mind and covers a broad base of medication classes. A majority of the editorial staff are pharmacists, which is appropriate. This is a U.K. publication, which means different education and training standards than the U.S., but the preface notes that the editorial team includes clinical pharmacists whose specialties range from community pharmacy to infectious diseases and HIV.
Features: The first chapter is an excellent overview of general drug interaction mechanisms and safety data. Subsequent chapters are categorized by pharmaceutical class or, in instances of numerous documented interactions, by drug, e.g. alcohol. Each chapter includes monographs outlining recognized drug interactions in a standardized format of abstract or summary, clinical evidence, mechanism, importance and management, and references. The book is effectively organized and delivers the content in an objective manner, a departure from most of these references, which assign a subjective rating to interactions. Overall, the book avoids using animal studies or in vitro data. However, in some instances, as in the antineoplastic chapter, these data are used and the authors provide a compelling rationale for their inclusion. Because it is a U.K. publication, readers from other countries with different regulatory bodies must keep this in mind. Some drugs may have a different name and/or spelling than the U.S. terminology for the same active ingredient. Thus, interpretation must be done to account for these nomenclature differences.
Assessment: This is a very useful, high quality reference. However, it does not contain the most up-to-date pharmacogenomic data. In recent years, there has been a great deal of growth in this area of pharmacology, with well-documented pharmacogenomic drug interaction data. This is briefly discussed in the introductory chapter and referenced with older citations. A chapter dedicated specifically to pharmacogenomic drug interactions would likely add value to this book. Since the body of evidence about drug interactions continues to grow and new drugs are continually introduced to the market, this update is justified.
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Product Details

  • ISBN-13: 9780853697541
  • Publisher: Pharmaceutical Press
  • Publication date: 11/28/2007
  • Series: Drug Interactions (Stockley) Series
  • Edition description: Older Edition
  • Edition number: 8
  • Pages: 1464

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