Strategy and Statistics in Clinical Trials: A non-statisticians guide to thinking, designing and executing

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Overview

Strategy and Statistics in Clinical Trials is for all individuals engaged in clinical research, including professors, physicians, researchers in corporate and government laboratories, nurses, members of the allied health professions, and post-doctoral and graduate students who are potentially less exposed to understanding the pivotal role of statistics.

•Enables nonstatisticians to better understand research processes and statistics' role in these processes •Offers real-life case studies and provides a practical, "how to" guide to biomedical R&D •Delineates the statistical building blocks and concepts of clinical trials •Promotes effective cooperation between statisticians and important other parties

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Product Details

  • ISBN-13: 9780123869098
  • Publisher: Elsevier Science
  • Publication date: 7/28/2011
  • Pages: 278
  • Sales rank: 1,429,352
  • Product dimensions: 7.70 (w) x 9.20 (h) x 0.80 (d)

Table of Contents

Chapter 1.) Clinical Development and Statistics: The General View

Chapter 2.) Questions when Planning Trials

Chapter 3.) Medical Product Attributes

Chapter 4.) Setting Research Objectives

Chapter 5.) Statistical Thinking

Chapter 6.) Estimation

Chapter 7.) From Description to Testing: A Beginning

Chapter 8.) Statistical Significance, Explanation and Prediction

Chapter 9.) Exploratory and Confirmatory Clinical Trials

Chapter 10.) One, Two, Three Testing: Hypothesis Testing and Multiplicity

Chapter 11.) Elements of Clinical Trial Design I: Putting it together

Chapter 12.) Elements of Clinical Trial Design II

Chapter 13.) Choosing Trial Endpoints

Chapter 14.) Determination of Sample Size

Chapter 15.) Concluding Remarks

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