Stress-Induced and Fear Circuitry Disorders: Refining the Research Agenda for DSM-V

Stress-Induced and Fear Circuitry Disorders: Refining the Research Agenda for DSM-V

by Gavin Andrews, Dennis S. Charney, Paul J. Sirovatka, Darrel A. Regier
     
 

As disorders in which stress or fear play major roles present an increasing need for psychiatric care around the world, this volume summarizes current research to determine whether a specific group of stress-induced and fear-based disorders form a distinct syndrome independent from other anxiety disorders such as obsessive-compulsive disorder or generalized anxiety

Overview

As disorders in which stress or fear play major roles present an increasing need for psychiatric care around the world, this volume summarizes current research to determine whether a specific group of stress-induced and fear-based disorders form a distinct syndrome independent from other anxiety disorders such as obsessive-compulsive disorder or generalized anxiety. Intended to suggest DSM-V revisions regarding the classification of these disorders, Stress-Induced and Fear Circuitry Disorders reflects findings that may lead to more refined treatments for these specific anxiety disorders based on a better understanding of the biological and environmental factors that contribute to their development and symptoms.

Thirty contributors, all international authorities on this group of mental illnesses, clarify how these disorders develop and what factors contribute to symptomatology. Focusing on posttraumatic stress disorder, panic disorder and agoraphobia, social phobias, and specific phobia, the authors explore the possibility of linking the classification and etiology of these conditions by showing that they may be closely related in terms of brain pathophysiology. In addition to assessing the stability of disorders across patient lifespans and determining whether they form a cohesive and distinct group, the authors examine shared etiologies and biopsychosocial correlates, as well as aspects unique to each disorder. Among the book's specific insights: • How minority populations, particularly African Americans, are differentially affected by these disorders.• The neuronal mechanisms of normal fear and anxiety, including how changes in the genetics of the serotonin system can increase the risk of anxiety.• The role of cognition in symptom presentation and treatment, revealing cognitive biases that favor the processing of threat-related information.• The contribution of stress and psychosocial factors, such as peer victimization and childhood sexual abuse.• The use of neuroimaging to analyze neural structure and function for each of the four disorder groups.• How neurochemistry and neuroendocrine markers may aid in classification of anxiety disorders.• The contribution of substance abuse to the pathophysiology of these disorders.

Given the importance of changes to DSM for professional education and public health, this book offers important new ways of thinking about stress-induced and fear-based disorders. It not only allows researchers to more accurately assess their diagnostic classifications, but also can help clinicians more effectively communicate with patients regarding the nature of their illness and the importance of adhering to treatment regimens.

American Psychiatric Publishing

Editorial Reviews

Doody's Review Service
Reviewer: Michael Joel Schrift, DO, MA (Northwestern University Feinberg School of Medicine)
Description: This interesting book summarizes current scientific data on whether post-traumatic stress disorder, panic disorder and agoraphobia, social phobia, and specific animal/situational phobias constitute a distinct fear-based and stress-induced syndrome. Written and edited by a group of nationally recognized clinician-scientists, this book offers a new conceptualization of these all too frequent and at times disabling disorders and is a welcome contribution to psychiatry.
Purpose: The editors note, "By offering important new ways of thinking about these disorders, the book not only allows researchers to more accurately assess these diagnostic classifications but also can help clinicians more effectively communicate with patients regarding the nature of their illness and its treatment."
Audience: The targeted audience includes researchers and clinicians.
Features: Part 1 describes the four stress-induced and fear circuitry disorders: post-traumatic stress disorder, panic disorder and agoraphobia, social phobia, and specific animal/situational phobias. The course and classification of anxiety disorders is covered in part 2. Part 3, on special topics, contains chapters on diverse topics such anxiety disorders in African Americans, the genetics of anxiety disorders, anxiety-related cognition, triggers, functional and structural brain imaging, the neurochemistry of anxiety and stress, and substance abuse and anxiety. Each chapter concludes with important and timely references to the scientific literature.
Assessment: Research into the pathophysiology of anxiety disorders is evolving rapidly and this book will give readers a glimpse into important new conceptualizations about these common problems. I highly recommend it.

Product Details

ISBN-13:
9780890423448
Publisher:
American Psychiatric Publishing, Incorporated
Publication date:
11/03/2008
Pages:
330
Product dimensions:
6.00(w) x 8.90(h) x 0.60(d)
Age Range:
18 Years

Meet the Author

Gavin Andrews, M.D., is a Professor of Psychiatry in the School of Psychiatry at University of New South Wales in Sydney, Australia.

Dennis S. Charney, M.D., is Dean of the Mount Sinai School of Medicine, Executive Vice President of Academic Affairs of the Mount Sinai Medical Center, and a Professor in the Departments of Psychiatry, Neuroscience, and Pharmacology & Systems Therapeutics at the Mount Sinai School of Medicine in New York, New York.

Paul J. Sirovatka, M.S. (1947-2007), was Associate Director for Research Policy Analysis, Division of Research/American Psychiatric Institute for Research and Education in Arlington, Virginia.

Darrel A. Regier, M.D., M.P.H., is Executive Director of the American Psychiatric Institute for Research and Education and Director of the Division of Research at the American Psychiatric Association in Arlington, Virginia.

American Psychiatric Publishing

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