Structure and Function in Cell Signalling / Edition 1

Structure and Function in Cell Signalling / Edition 1

by John Nelson
     
 

"Structure and Function in Cell Signalling is an introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities - the 'nuts and bolts' of cellular information exchange." The book teaches the… See more details below

Overview

"Structure and Function in Cell Signalling is an introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities - the 'nuts and bolts' of cellular information exchange." The book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding.

Product Details

ISBN-13:
9780470025505
Publisher:
Wiley
Publication date:
09/02/2008
Pages:
410
Product dimensions:
6.90(w) x 9.90(h) x 1.00(d)

Table of Contents

1 The components and foundations of signalling 1

2 Enzymes and receptors - quantitative aspects 39

3 Modules and motifs in transduction 71

4 Protein kinase enzymes - activation and auto-inhibition 101

5 7-pass receptors and the catabolic response 133

6 Single pass growth factor receptors 179

7 G proteins (I) - monomeric G proteins 215

8 G proteins (II) - heterotrimeric G proteins 245

9 The insulin receptor and the anabolic response 271

10 Mitogens and cell cycle progression 297

App. 1 Worked examples 355

App. 2 RasMol: installation and use 365

Index 377

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