Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding / Edition 1 by Alan Fersht | 9780716732686 | Hardcover | Barnes & Noble
Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding / Edition 1

Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding / Edition 1

by Alan Fersht
     
 

ISBN-10: 0716732688

ISBN-13: 9780716732686

Pub. Date: 09/15/1998

Publisher: Freeman, W. H. & Company

Fersht's Structure and Mechanism in Protein Science is a defining exploration of this new era, an expert depiction of the core principles of protein structure, activity, and mechanism as understood and applied today. A thorough recasting of Fersht's previous text, the book takes a more general look at mechanisms in protein science, emphasizing the unity of

Overview

Fersht's Structure and Mechanism in Protein Science is a defining exploration of this new era, an expert depiction of the core principles of protein structure, activity, and mechanism as understood and applied today. A thorough recasting of Fersht's previous text, the book takes a more general look at mechanisms in protein science, emphasizing the unity of concepts in folding and catalysis and the importance of the relationships between basic chemistry, kinetics, thermodynamics, and structure.

Product Details

ISBN-13:
9780716732686
Publisher:
Freeman, W. H. & Company
Publication date:
09/15/1998
Edition description:
First Edition
Pages:
650
Product dimensions:
6.32(w) x 9.42(h) x 1.42(d)

Table of Contents

1. The Three-dimensional Structure of Proteins
2. Chemical Catalysis
3. The Basic Equations of Enzyme Kinetics
4. Measurement and Magnitude of Enzymatic Rate Constants
5. The pH Dependence of Enzyme Catalysis
6. Practical Kinetics
7. Detection of Intermediates in Reactions by Kinetics
8. Stereochemistry of Enzymatic Reactions
9. Active-site-directed and Enzyme-activated Irreversible Inhibitors: Affinity Labels and Suicide Inhibitors
10. Conformational Change, Allosteric Regulation, Motors, and Work
11. Forces Between Molecules and Enzyme-Substrate Binding Energies
12. Enzyme-substrate Complementarity and the Use of Binding Energies in Catalysis
13. Specificity and Editing Mechanisms
14. Recombinant DNA Technology
15. Case Studies of Enzyme Structure and Mechanism
16. Protein Engineering
17. Protein Stability
18. Kinetics of Protein Folding
19. Folding Pathways and Energy Landscapes

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