Studies In Natural Products Chemistry

Studies In Natural Products Chemistry

by Atta-ur-Rahman
     
 

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ISBN-10: 0444893660

ISBN-13: 9780444893666

Pub. Date: 01/01/1993

Publisher: Elsevier Science

Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines.
Some

Overview

Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines.
Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound. The complete synthesis of erythromycin A is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an A-Ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes.
The book can provide useful information to chemists, biologists, students, and researchers.

Product Details

ISBN-13:
9780444893666
Publisher:
Elsevier Science
Publication date:
01/01/1993
Series:
Studies in Natural Products Chemistry
Pages:
544
Product dimensions:
1.38(w) x 6.00(h) x 9.00(d)

Table of Contents

Foreword. Total synthesis of polycarbocyclic marine terpenoids (J.D. Martin). Stereoselective total syntheses of spongian-type diterpenes and scalarane-type sesterterpenes of metabolites from marine sponge organisms (T. Nakano). Allenic and acetylenic carotenoids (S. Liaaen-Jensen). Synthetic studies on gibberellins and antheridiogens (L.N. Mander). Recent advances in the chemistry of secondary metabolites isolated from Fusarium species (M.E. Savard et al.) Amphotericin B: synthetic studies (O.S. Chizhov). Development of dithioacetal S-oxides and S,S-dioxides as synthetic reagents (K. Ogura). Sugar analogs containing carbon-phosphorus bonds (H. Yamamoto, T. Hanaya). Syntheses and reactions of sugar-peptide structures related to cell-wall peptidoglycan from bacteria (D. Keglević). Chemical defense in ants (J.C. Braekman, D. Daloze). Some aspects of heterocyclic chemistry related to isoquinoline-derived alkaloids (J.B. Bremner). Alkaloids of Strychnos dinklagei: structure and chemistry (S. Michel et al.). Chiral synthesis of natural products as semiochemicals and bioregulators (T. Kitahara). Subject Index.

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