Surgical Pathology of the Nervous System and its Coverings / Edition 3

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The most comprehensive book on this subject, this essential resource explores diagnostic and differential diagnostic criteria for all neoplastic, inflammatory, and infectious diseases of the central and peripheral nervous system. Inside the 4th Edition, readers will find expanded coverage of infectious and inflammatory diseases*the latest knowledge on dementia and seizures*new information on the molecular and pathogenetic aspects of brain tumors*and many other vital updates!

• Two new chapters: (Chapter 5) The Brain-Stereotactically-Directed Needle Biopsy and (Chaper 6) The Brain-Surgery for Seizures.
• Includes new or expanded coverage of infectious and inflammatory diseases, rare prion diseases and dementia.
• Revises and updates the brain tumour section to include new entities and to detail the relation of brain tumours to the underlying molecular and pathogenetic features associated with these diseases.

".a well illustrated revision of a diagnostic reference that provides descriptions of all pathologic entities that affect the nervous system & its coverings...includes expanded coverage of AIDS & a brand new chapter on vascular disease."

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Editorial Reviews

Doody's Review Service
Reviewer: John Mark Oscherwitz, M.D.(University of Kansas School of Medicine)
Description: In this comprehensive neuropathology book, the authors cover neoplastic and inflammatory disorders of the brain and spinal cord frequently encountered by the surgical pathologist. The book is very well organized and contains unique diagnostic checklists to aid in the differential diagnosis. The authors have upgraded this fourth edition from the previous edition published in 1991.
Purpose: The authors' purpose is to cover the surgical aspects of neuropathology. There is certainly a place in surgical pathology and neuropathology for such a high quality book. The authors have surpassed their goal with this well-illustrated new edition.
Audience: The intended readers of this book are pathologists, residents and fellows in neuropathology, as well as neurologists, neurosurgeons, and their trainees. The three authors are well known writers and respected experts in the field.
Features: Covered in the book are tumors of the brain, meninges, spinal cord, and peripheral nerves as well as inflammatory and infectious diseases of the nervous system. From astrocytomas to histiocytosis of the skull, the authors have covered the mundane to the rare neuropathologic diagnosis. The first chapter covers diseases involving the skull, such as fibrous dysplasia and Paget's disease. The chapter covering brain tumors is particularly well written. The book is extensively illustrated with top-notch gross and microscopic color photographs, along with excellent electron micrographs and radiographs. The authors have organized the book into clinical, gross, microscopic, immunohistochemical, molecular, radiographic, and differential diagnostic categories which allows for easy referencing. Also included are diagnostic checklists that highlight important conditions to consider in the differential diagnosis and frequent pitfalls to avoid.
Assessment: This is an excellent, well illustrated book for pathologists and clinicians alike. The authors' hard work on this latest edition has resulted in an outstanding book, one of the finest in neuropathology.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780443086878
  • Publisher: Elsevier Health Sciences
  • Publication date: 10/15/1990
  • Edition description: Older Edition
  • Edition number: 3
  • Pages: 751

Meet the Author

Professor, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD

Professor, Department of Pathology, Mayo Medical School; Consultant in Surgical Pathology, Mayo Clinic, Rochester, MN

Professor Emeritus, Department of Pathology, Duke University School of Medicine, Durham, NC

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Table of Contents

1 Skull and Related Soft Tissues 1
Non-Neoplastic Conditions 1
Benign Neoplasms 13
Malignant Neoplasms 23
Developmental Anomalies 32
2 Intracranial Meninges 49
Benign Neoplasms and Non-Neoplastic Tumors 49
Primary Malignant Neoplasms 79
Secondary Malignant Neoplasms 88
Benign Cystic Lesions 89
Infectious and Inflammatory Disorders 93
Other Reactive Conditions and Noninflammatory Pseudotumors 99
3 The Brain: Inflammatory Disorders 113
Demyelinating Diseases 113
Bacterial Infections 119
Viral Infections 127
Fungal Infections 134
Protozoal Infections 140
Parasitic Infections 144
Acquired Immunodeficiency Syndrome 145
Sarcoidosis 146
Other Inflammatory Diseases 146
4 The Brain: Tumors 160
Primary Neoplasms 161
Metastatic Neoplasms 346
5 The Brain: Sterotactically Directed Needle Biopsy 379
Indications 379
Target Selection 379
Specimen Preparation 382
Specimen Analysis 384
Correlation of Clinical, Radiologic, and Pathologic Findings 385
Communication 389
6 The Brain: Surgery for Seizures 390
Neoplasms and Non-Neoplastic Mass Lesions 390
Non-Neoplastic Lesions 392
7 The Brain: Vascular Disease 403
Vascular Malformations 403
Vasculitis and Vasculopathy 408
Cerebral Infarct 414
Subdural Hematoma 417
8 The Brain: Biopsy for Dementia 424
Creutzfeldt-Jakob Disease 424
Alzheimer's Disease and Neurodegenerative Changes of the Alzheimer Type 427
Dementia with Lewy Bodies 430
Pick's Disease and Other Non-Alzheimer Tauopathies 431
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukodystrophy (CADASIL) 434
9 Region of the Sella Turcica 437
Normal Anatomy of the Pituitary 437
Pituitary Neoplasia 441
Pituitary Hyperplasia 472
Pituicytoma (Infundibuloma) and Granular Cell Tumor of the Infundibulum 473
Craniopharyngiomas 475
Miscellaneous Neoplasms and Tumor-Like Lesions 483
Sellar Region Cysts 484
Inflammatory Lesions 487
Infectious Lesions 489
Miscellaneous Non-Neoplastic Processes 490
Empty Sella Syndrome 490
10 Spine and Epidural Space 499
Congenital Malformations (Meningocele and Meningomyelocele) 499
Inflammatory Disorders 500
Degenerative and Reactive Processes 503
Neoplasms and Other Tumors 508
11 Spinal Meninges, Spinal Nerve Roots, and Spinal Cord 527
Spinal Meninges 527
Spinal Nerve Roots 540
Spinal Cord 544
12 The Peripheral Nervous System 579
Specimen Assessment 580
Normal Anatomy 580
Reactive Lesions 585
Inflammatory and Infectious Lesions Simulating Tumor 591
Hamartoma and Choristoma 592
Benign Peripheral Nerve Sheath Tumors 594
Primary Malignant Tumors of Nerve 623
Metastatic Neoplasms 633
Neurofibromatosis 635
App Differential Diagnosis of Tumors and Tumor-Like Lesions of Nerve 640
Index 649
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