Overview

Systemic Lupus Erythematosus, Fourth Edition, provides an understanding of the basic mechanisms as well as the diagnostic and therapeutic aspects of lupus. This book is attractive to both the investigative community and clinicians. As lupus has become a paradigm for the study of autoimmune disease, immunologists investigating autoimmunity are becoming more interested in lupus. Basic immunology of phospholipid antibodies, clotting abnormailities, issues concerning pathogenetic fit with SLE, and newest methods of ...
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Systemic Lupus Erythematosus

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Overview

Systemic Lupus Erythematosus, Fourth Edition, provides an understanding of the basic mechanisms as well as the diagnostic and therapeutic aspects of lupus. This book is attractive to both the investigative community and clinicians. As lupus has become a paradigm for the study of autoimmune disease, immunologists investigating autoimmunity are becoming more interested in lupus. Basic immunology of phospholipid antibodies, clotting abnormailities, issues concerning pathogenetic fit with SLE, and newest methods of therapy of APLS are given in this newest edition of a classic reference.

* Comprehensive current coverage of basic models of etiology and pathogenesis
* Complete catalog of autoantibodies produced
* Includes an outstanding review of imaging techniques for the diagnosis of lupus and its complications for each organ system
* Includes CD-ROM of images excellent for teaching purposes and downloading into presentations

Audience: Immunologists, rheumatologists, basic and clinical researchers, and investigators studying lupus and other autoimmune diseases.

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Editorial Reviews

From the Publisher
Published Review of Fourth Edition
"The editor's purpose is to provide the reader with the latest information about SLE, its science, presentation, and treatment.This edition of Systemic Lupus Erythematosus continues to be an up-to-date, comprehensive, and well-referenced resource for both the basic science and clinical medicine aspects of this complex disease. The book takes us on a journey starting with the disease pathogenesis, continuing with animal models of lupus, various autoantibodies and antigens, the clinical approach to diagnosis and the affected organs and tissues, and ending with current therapies. It will be an excellent reference book for students of immunology/rheumatology and for experienced research scientists and clinicians. Reflecting the emerging information in this dynamic field, the volume includes new chapters on fibromyalgia and osteoporosis in association with SLE, and enhanced chapters on the molecular aspects of the cellular immunology of SLE, the neuropsychiatric aspects of SLE, and the various aspects of antiphospholipid syndrome. The addition of a searchable CD-ROM makes it easier to identify the updated information and to download the images for educational purposes. The chapters are written by experts in their respective fields, and each chapter independently represents a piece of the lupus puzzle. As Dr Lahita states in the introduction, "Reading the chapters in this book will not solve the mystery, but it will give you the impression that we are close to understanding the illness."
-Rheumatology, 2004

Published Review of Third Edition:
"This book successfully links basic science with clinical medicine, providing a framework within which to understand this complex disease. As Lahita states in the introduction, 'The history of discovery is now in the log phase of growth.' The third edition of Systemic Lupus Erythematosus conveys the excitement and the breadth of this dynamic field. This volume will be an excellent resource for basic and clinical scientists, as well as for the students of imunology and rheumatology. The chapters are well-referenced and can be read independently- as befits a reference book."
-Jane E. Salmon, Weill Medical College, Cornell University, New York, USA (March 2000)

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Product Details

  • ISBN-13: 9780080474540
  • Publisher: Elsevier Science
  • Publication date: 6/9/2004
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 4
  • Pages: 1343
  • File size: 38 MB
  • Note: This product may take a few minutes to download.

Read an Excerpt

No other Lupus text provides such an amalgam of basic research and clinical practice of the highest caliber
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Table of Contents

Topics Include
Introduction to 4th Edition
Pathogenesis
Autoimmunity and Autoimmune Diseases like Systemic Lupus Erythematosus
Overview of Cellular Immune Function in Systemic Lupus Erythematosus
Etiopathogenesis of Systemic Lupus Erythematosus: The Itineraries of Three Troikas
MHC Class II and Non-MHC Genes in the Pathogenesis of Systemic Lupus Erythematosus
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