T-Cell Paradigms in Parasitic and Bacterial Infections

Overview

This volume deals with various aspects of the intricate relation of bacterial and parasitic pathogens with the immune system. It provides new insights into how the immune system succeeds to eradicate its predators and how it can fail. Chapters in this book summarize novel information about the role of helper T-cell subsets and cytolytic T cells in antimicrobial immunity and the possible relation between anti-infectious and autoimmune responses, and discuss the most recent approaches to the definition of T-cell ...
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Overview

This volume deals with various aspects of the intricate relation of bacterial and parasitic pathogens with the immune system. It provides new insights into how the immune system succeeds to eradicate its predators and how it can fail. Chapters in this book summarize novel information about the role of helper T-cell subsets and cytolytic T cells in antimicrobial immunity and the possible relation between anti-infectious and autoimmune responses, and discuss the most recent approaches to the definition of T-cell epitopes and to the construction of recombinant carriers. Both experimental systems and theoretical considerations related to these topics are covered.
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Product Details

Table of Contents

Schistosoma.- T-Cell Antigens and Epitopes in Schistosomiasis.- Cell-Mediated Immune Response to Schistosomiasis.- Protozoa.- T-Cell Subsets and T-Cell Antigens in Protective Immunity Against Experimental Leishmaniasis.- Regulation of Cell-Mediated Immunity in Leishmaniasis.- T-Cell Antigens and Epitopes in Malaria Vaccine Design.- Cytotoxic T Cells and Immunity to Theileria parva in Cattle.- Bacteria.- T-Lymphocytes in Leprosy Lesions.- Antigen Reactivity and Autoreactivity: Two Sides of the Cellular Immune Response Induced by Mycobacteria.- Antigens and Carriers.- T Cells, Stress Proteins, and Pathogenesis of Mycobacterial Infections.- Prediction and Identification of Bacterial and Parasitic T-Cell Antigens and Determinants.- Development of BCG As a Recombinant Vaccine Vehicle.
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