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Targeted Cancer Therapy / Edition 1

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Overview

In the era of personalized medicine, cancer treatment has become a model for the use of targeted therapeutics. Leaving behind the "one size fits all" approach to cancer care, this book provides the practicing oncologist with an overview of the advances in treatment and an understanding of the implementation of new therapeutic agents. Targeted Cancer Therapy is divided into twenty chapters covering specific hematologic malignancies and solid tumors, targeted and functional imaging, and combination therapies. Each disease specific chapter includes up-to-date information on investigational and FDA approved therapies which will enhance the reader's ability to prescribe effective drug regimens. This includes combinations of therapies and therapeutic modalities to overcome drug resistance.

In a rapidly changing field, this book will enable clinicians to improve their ability to practice personalized health planning, make early diagnoses, and select optimal drugs for each patient with predictable side effects and outcomes. Poised to change the landscape in oncology, Targeted Cancer Therapy is essential for practicing and academic physicians, fellows, and residents.

Features

Will optimize the reader's ability to prescribe effective therapeutic regimens

Provides know-how on building drug combinations that overcome disease resistance

Illustrates the use of personalized medicine in cancer treatment

Divided into clearly organized, site specific chapters

Presents the forefront in the practical implementation of targeted therapeutics

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Editorial Reviews

From the Publisher
From the reviews:

“Targeted Cancer Therapy provides an overview of recent advancements in therapy deriving from the implementation of new therapeutic agents. … this book represents a useful and stimulating publication. … the book has a scientific and cultural appeal for many other professionals interacting with patients with neoplastic disease. … we also suggest this volume to all students who want to grow into becoming protagonists in the new era of molecular medicine.” (Luigi Mansi and Andrea Vaccaro, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 39, 2012)

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Product Details

  • ISBN-13: 9781603274234
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 4/28/2008
  • Series: Current Clinical Oncology Series
  • Edition description: 2008
  • Edition number: 1
  • Pages: 446
  • Product dimensions: 6.90 (w) x 10.10 (h) x 1.20 (d)

Table of Contents

Preface vii

Contributors xi

1 Perspectives: Bench to Bedside and Back Jennifer Wheler Razelle Kurzrock 1

2 Targeted Therapy in Acute Myelogenous Leukemia Elihu Estey 21

3 Targeted Therapy in Breast Cancer Barbara S. Craft Stacy Moulder 43

4 Targeted Therapy in Chronic Lymphocytic Leukemia Apostolia-Maria Tsimberidou Michael J. Keating 61

5 Targeted Therapy in Chronic Myeloid Leukemia Elias Jabbour Jorge Cortes Hagop Kantarjian 87

6 Targeted Therapy in Colorectal Cancer Scott Kopetz 101

7 Targeted Therapy in Non-Small Cell Lung Cancer David J. Stewart 125

8 Targeted Therapy in Lymphoma Amanda Wedgwood Anas Younes 157

9 Targeted Therapy in Melanoma Michael Davies Sunil Patel Kevin B. Kim 183

10 Targeted Therapy in Multiple Myeloma Yuhong Zhou Raymond Alexanian Michael Wang 213

11 Targeted Therapy in Myelodysplasia Syndrome Alfonso Quintás-Cardama Hagop Kantarjian Guillermo Garcia-Manero Jorge Cortes 237

12 Targeted Therapy in Epithelial Ovarian Cancer Maurie Markman 261

13 Targeted Drug Therapy in Pancreatic Cancer Don L. Gibbons Robert A. Wolff Gauri Varadhachary 271

14 Targeted Therapy in Prostate Cancer Amado J. Zurita John F. Ward Jeri Kim 289

15 Targeted Therapy in Renal Cell Carcinoma Eric Jonasch Nizar Tannir 305

16 Targeted Therapy of Sarcoma Joseph Ludwig Jonathan C. Trent 317

17 Targeted and Functional Imaging Vikas Kundra Dawid Schellingerhout Edward F. Jackson 335

18 Combining Targeted Therapies David Hong Lakshmi Chintala 361

19 Drug Development in Cancer Medicine: Challenges for Targeted Approaches Luis H. Camacho 383

20 Toward Personalized Therapy for Cancer Sarah J. Welsh Garth Fowis 411

Index 427

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