Tectona Grandis - A Useful Herb

Tectona Grandis - A Useful Herb

by Jitendra Bhangale, S. R. Chaudhari, S. R. Acharya
     
 
The aqueous extract of Tectona grandis bark (ATG) was investigated for anti-inflammatory and antinociceptive activity at the doses (p.o.) of 100, 200 and 400 mg/kg body weight. The acetic acid-induced writhing response, tail immersion test and hot plate test were used to assess antino-ciceptive activity. For evaluation of anti-inflammatory activity, carrageenan

Overview

The aqueous extract of Tectona grandis bark (ATG) was investigated for anti-inflammatory and antinociceptive activity at the doses (p.o.) of 100, 200 and 400 mg/kg body weight. The acetic acid-induced writhing response, tail immersion test and hot plate test were used to assess antino-ciceptive activity. For evaluation of anti-inflammatory activity, carrageenan induced paw edema served as acute model. At a dose, ATG (100, 200 and 400 mg/kg, p.o.) significantly attenuated the writhing responses induced by an intraperitoneal injection of acetic acid and at ATG (200 and 400 mg/kg, p.o.) significantly increased pain latencies in tail immersion and hot plate test. In addition, the higher doses of ATG (200 and 400 mg/kg, p.o.) were inhibited carrageenan induced paw edema. From acute oral toxicity studies (OECD-423 guidelines), no mortality was observed even at highest dose of ATG (2000 mg/kg, p.o.).

Product Details

ISBN-13:
9783659000607
Publisher:
OmniScriptum GmbH & Co. KG
Publication date:
06/14/2012
Pages:
88
Product dimensions:
6.00(w) x 9.00(h) x 0.21(d)

Customer Reviews

Average Review:

Write a Review

and post it to your social network

     

Most Helpful Customer Reviews

See all customer reviews >