Testosterone and Aging: Clinical Research Directions

Testosterone and Aging: Clinical Research Directions

by Catharyn T. Liverman, Dan G. Blazer, Committee on Assessing the Need for Clinical Trials of Testosterone Replacement Therapy
     
 

Popular culture often equates testosterone with virility, strength, and the macho male physique. Viewed by some as an “antiaging tonic,” testosterone’s reputation and increased use by men of all ages in the United States have outpaced the scientific evidence about its potential benefits and risks. In particular there has been growing concern about an… See more details below

Overview

Popular culture often equates testosterone with virility, strength, and the macho male physique. Viewed by some as an “antiaging tonic,” testosterone’s reputation and increased use by men of all ages in the United States have outpaced the scientific evidence about its potential benefits and risks. In particular there has been growing concern about an increase in the number of middle-aged and older men using testosterone and the lack of scientific data on the effect it may have on aging males. Studies of testosterone replacement therapy in older men have generally been of short duration, involving small numbers of participants and often lacking adequate controls. Testosterone and Aging weighs the options of future research directions, examines the risks and benefits of testosterone replacement therapy, assesses the potential public health impact of such therapy in the United States, and considers ethical issues related to the conduct of clinical trials. Testosterone therapy remains an attractive option to many men even as speculation abounds regarding its potential.

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Product Details

ISBN-13:
9780309090636
Publisher:
National Academies Press
Publication date:
02/16/2004
Pages:
240
Product dimensions:
6.00(w) x 8.90(h) x 0.60(d)

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Table of Contents

1Introduction11
2Testosterone and health outcomes32
3Future research directions112
4Concluding remarks159
AppRandomized placebo-controlled trials of testosterone
AppTherapy in older men
AppAdditional studies of testosterone therapy
AppTestosterone levels in clinical studies

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