Textbook of Endocrine Physiology / Edition 5

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Overview

This widely used text provides a thoroughly updated account of current knowledge in the endocrine sciences. Each chapter is structured to cover both established concepts and recent developments. The chapters are not only written at a consistent level and well integrated with one another, but they also blend basic science with essential elements of clinical knowledge in order to give students an appreciation of the consequences of deranged endocrine function. The Fifth Edition features completely new versions of the chapters on "Cytokines and Immune-Endocrine Interactions," "The Adrenal Glands," and "Calcium Homeostasis." Many of the illustrations throughout the book are new or have been significantly revised to complement the revised text. Fresh examples have also been included so that each chapter continues to show clearly the clinical consequences of deranged endocrine function. Much new scientific information has been added on such topics as the nongenomic actions of steroid hormones, relaxin receptors, inhibin B, steroid regulating element-binding proteins, IGF-binding proteins, transcriptional regulation of the developing adipocyte, and the regulation of food intake and body weight.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: John Leonora, PhD (Loma Linda University)
Description: This is an update on the current understanding of endocrine physiology.
Purpose: The purpose is to present current endocrine physiology at a level suitable, presumably, for medical and graduate students who are early in their training. This is noble objective. However, when one considers the diversity in the academic background of many of these students, this objective is difficult to attain. Most of the book meets the author's objective. There are parts where this goal may not be reached due to the difficulty of the material, particularly in the area of molecular biology.
Audience: The book, according to the authors, is geared primarily to medical students and graduate students in the basic sciences (physiology, biochemistry, and pharmacology). In general, I concur with the authors.
Features: All of the major endocrine systems are presented well with up-to-date information. A shortcoming of the book is that in certain areas the gene expression and molecular transformation of protein hormones is overdone. The reading can be hard going and frustrating if the reader doesn't have the necessary background. This information is relevant only for those who have a particular interest in this area and may be contemplating research. The general student who will be reading this book is primarily interested in an overview and not in minute detail.
Assessment: The quality of the book is good. A number of years ago, I recommended a previous edition to medical and graduate physiology students. The book is useful provided you can get students to read it. I believe this book will stack up well against comparable books. This edition justifies replacing the earlier editions.
Michael W. Wolfe
This textbook discusses the basic concepts of endocrinology and then builds on these concepts to develop an understanding of the complexities of endocrine function and endocrine disorders. The first few chapters provide a general overview of the endocrine system as well as important concepts that are of overall importance. Subsequent chapters discuss specific endocrine systems in more depth. This book is intended to provide graduate and medical students a basic understanding of endocrine function. It is also useful as a general reference resource regarding endocrine systems. The authors have written this text at a level such that students and others that are new to the discipline of endocrinology can quickly and easily obtain a basic understanding of endocrine function. Important terms have been italicized and defined to aid the reader in this learning process. The author's have used an impressive array of illustrations to help clarify and reinforce important concepts. They include such things as chemical structures, gene structures, pathways involved in endocrine signaling, and anatomy of endocrine glands. These illustrations are a major strength of this text in that they add to its effectiveness as a teaching tool. Equally as important, the authors have seen to it that this third edition includes new scientific information pertinent to understanding endocrine function. This is of particular significance due to the volume of recently published molecular biological data as well as information involving cell signaling. This is an excellent up-to-date text for teaching basic endocrine function. It is clearly written and easy to read, and the chapters follow a logical progression fromthe establishment of the basics to development of more complex concepts, including specific endocrine disorders. Furthermore, the illustrations are informative and presented at key spots to reinforce and clarify concepts.
Russell Szmulewitz
This is a thorough and detailed description of endocrine physiology and anatomy, with insights into clinical endocrinology and relevant scientific techniques. According to the editors, the purposes include providing a clear understanding of basic endocrinology, forming a framework for understanding clinical disruptions in normal endocrine physiology, and giving descriptions of key scientific techniques used in endocrinology research. These are definitely worthy goals, and the editors achieve their purpose. The editors state in the preface that the target audience is medical students and graduate students. Given the purpose and overall tone and level of detail, the audience is appropriately targeted. However, prior exposure to the field is helpful. Regarding the credibility of the contributors, it is clear that all of the chapters are written by experts in their given fields. All aspects of endocrinology are addressed, from a detailed introduction of hormones to immune system interactions to specific topics in endocrinology. In my view, the highlights are the coverage of specific endocrine topics, particularly thyroid, and sexual physiology. The textbook is also unique in the contributors' description of research techniques. There are three shortcomings. In an effort to compartmentalize and organize the different topics separately, the editors often fail to interconnect ideas. In addition, they overemphasize more recent discoveries in endocrinology. Finally, they do not include enough diagrams and photographs to help concretize their points. This is a very well written detailed account of endocrinology that is more thorough than a basic physiology text, but the editors fail toinclude as much clinically relevant material as Greenspan's Basic and Clinical Endocrinology, 6th Edition (Prentice Hall Health, 2001). This is a useful text, particularly as a reference for more advanced study for graduate and medical students.
From the Publisher

From reviews of previous editions

"This text succeeds in providing excellent, very readable coverage of the field of endocrinology. The consistent clearness of writing is commendable. This text can be highly recommended for graduate level courses and for medical students beyond the first year."--Endocrine News

"...the expertise of the contributors in their fields is evident throughout, and the approach and level of detail are appropriate in the UK for second-year preclinical students, for those studying endocrine options, and for those in clinical years needing to refresh and apply their knowledge of physiology."--Experimental Physiology

"In summary, this textbook incorporates modern concepts in an excellent, readable, concise, and comprehensive introduction or review of endocrine physiology."--Annals of the Royal College of Physicians and Surgeons of Canada

"The coverage, readability, currency, and cost make Griffin and Ojeda's newest edition a best buy for classroom use or overall review purposes."--TEM


3 Stars from Doody
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Product Details

  • ISBN-13: 9780195165661
  • Publisher: Oxford University Press
  • Publication date: 4/28/2004
  • Edition description: Older Edition
  • Edition number: 5
  • Pages: 448
  • Product dimensions: 9.10 (w) x 6.10 (h) x 1.10 (d)

Table of Contents

1. Organization of the Endocrine System, Sergio R. Ojeda and James E. Griffin

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