NFisherMA
Posted July 20, 2009
This text handsomely bridges the overlapping territories of nephrologists, endocrinologists and cardiologists. The editors have collected a top-notch group of experts to provide in-depth lessons in physiology and therapeutics suitable for academics, clinicians and researchers. Topics include the kidney as an endocrine organ (erythropoietin, Vitamin D, PTH, and the renin-angiotensin-aldosterone system), as well as the kidney as hormonal target (ADH, ANP/BNP, aldosterone). A valuable detailed resource of highest quality.
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Posted May 14, 2009
This excellent book is written to enlighten the novice and extend the knowledge base of the established investigator. The information will be of value to master's or PhD trainees, medical students, students in other biomedical professional disciplines, scientists in industry, practicing clinical investigators and administrators in the broad fields of nephrology and endocrinology.
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More About This Textbook
Overview
The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers both researchers and clinicians expert, gold-standard analysis of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoprosis, and, hypoparathyroidism.
• Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems.
• Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work.
• Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field.
Editorial Reviews
From the Publisher
"Singh and Williams have clearly chosen their authors well. The experts responsible for each chapter are clearly very knowledgeable and did an outstanding job of sharing that knowledge with the reader. Very often in books of this kind the density of the detail makes the reading rather difficult. Not in the case of this monograph. The reading is easy" —-Norman K. Hollenberg, M.D., Ph.D., Department of Medicine, Brigham and Women's Hospital, Harvard, Boston, MA, USA"This well-written, relatively concise, and current book will find a home on the shelves of many nephrologists and endocrinologists. Because it is so readable, it should be useful for students, experts, and those in between. I know I will consult my copy on a frequent basis — an unusual event in this era of online material."
— As reviewed in N Engl J Med 2009; 361: 832
"All in all, this is a solid book that provides substantial up-todate information on endocrine aspects of the kidney. I will be glad to pull it down from my shelf rather than one of the true heavyweights to which I would previously have gone for this kind of reading." — Kidney International (2009)
Product Details
Related Subjects
Table of Contents
Part 1: The Kidney as an Endocrine Organ
Section 1: Erythropoietin
1.Erythropoientin: An Historical Overview of Physiology, Molecular Biology And Gene Regulation
2.Erythropoiesis: The Role of Erythropoietin and Iron
3.Extra-Hematopoietic Action of Erythropoietin
4.Development of Recombinant Erythropoietin and Erythropoietin Analogues
5.Erythropoietin Disease States & Resistance
Section 2: Vitamin D, PTH and Novel Regulators of Phosphate
6. Vitamin D and the Kidney: Introduction and Historical Perspective
7.Vitamin D: Molecular Biology and Gene Regulation
8.Molecular Biology of Parathyroid Hormone
9.Endocrine Regulation of Phosphate Homeostasis
Section 3: Renin-angiotensin
10.Introduction and Historical Overview
11.Molecular Biology of Renin and Regulation of Its Gene
12. Physiology and Regulation of the RAAS System
13. The Renin Angiotensin Aldosterone System and the Kidney
14. The Renin Angiotensin and the Heart
15. The Renin-Angrotensin blockade: Therapeutic Agents
Part 2: The Kidney as a Hormonal target
Section 4: Anti-diuretic Hormone
16. Vasopressin in the Kidney: Historical Aspects
17. Molecular Biology and Gene Regulation
18. Vasopressin Antagonists in Physiology and Disease
19. Diabetes Insipidus and SIADH
Section 5: The Atrial Natriuretic Peptides
20. ANP, BNP and CNP Physiology and Pharmacology of the Cardiorenal Axis
Section 6: Aldosterone
21.Introduction and Historical Overview
22.Aldosterone Receptors and Their Renal Effects: Molecular Biology
And Gene Regulation
23. Aldosterone and Its Cardiovascular Effects
24. Aldosterone Regulation
Section 7: Endocrine Disorders in Renal Failure
25. Insulin resistance
26. Growth hormone
27. Sexual Dysfunction in Men and Women with Chronic Kidney Disease
28. Thyroid Status in Chronic Renal Failure Patients
29.Metabolic Acidosis of Chronic Kidney Disease
30.Pregnancy and the Kidney