Textbook of Neural Repair and Rehabilitation, Volume 1: Neural Repair and Plasticityby Michael Selzer
Pub. Date: 01/31/2006
Publisher: Cambridge University Press
In two freestanding volumes, Textbook of Neural Repair and Rehabilitation provides comprehensive coverage of the science and practice of neurological rehabilitation. This volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing anatomical and physiological plasticity in the normal CNS, mechanisms of neuronal death, axonal regeneration, stem cell biology, and neuron replacement. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.
- Cambridge University Press
- Publication date:
- Edition description:
- Older Edition
- Product dimensions:
- 7.44(w) x 9.69(h) x 1.54(d)
Table of ContentsPreface; Neural repair and rehabilitation: an introduction; Part A. Neural plasticity: Part A1. Cellular and molecular mechanisms of neural plasticity: 1 Anatomical and biochemical plasticity of neurons: regenerative growth of axons, sprouting, pruning, and denervation; supersensitivity; 2 Learning and memory: basic principles and model systems; 3 Short-term plasticity: facilitation and post-tetanic potentiation; 4 Long-term potentiation and long-term depression; 5 Cellular and molecular mechanisms of associative and nonassociative learning; Part A2. Functional Plasticity in CNS System: 6 Plasticity of mature and developing somatosensory systems; 7 Activity-dependent plasticity in the intact spinal cord; 8 Plasticity of cerebral motor functions: implications for repair and rehabilitation; 9 Plasticity in visual connections: retinal ganglion cell axonal development and regeneration; 10 Plasticity in auditory functions; 11 Cross-modal plasticity in sensory systems; 12 Attentional modulation of cortical plasticity; Section A3. Plasticity after injury to the CNS; 13 Plasticity in the injured spinal cord; 14 Plasticity after brain lesions; 15 From bench to bedside: influence of theories of plasticity on human neurorehabilitation; Part B. Neural Repair: Part B1. Basic Cellular and Molecular Processes: 16 Neuronal death and rescue: neurotrophic factors and anti-apoptotic mechanisms; 17 Axon degeneration and rescue; 18 Adult neurogenesis and neural precursors, progenitors, and stem cells in the adult CNS; 19 Axon guidance during development and regeneration; 20 Synaptogenesis; Part B2. Determinants of Regeneration in the Injured Nervous System: 21 Inhibitors of axonal regeneration; 22 Effects of the glial scar and extracellular matrix molecules on axon regeneration; 23 Trophic factors and their influence on regeneration; 24 Intraneuronal determinants of regeneration; Part B3. Promotion of Regeneration in the Injured Nervous System: 25 Cell replacement in spinal cord injury; 26 Dysfunction and recovery in demyelinated and dysmyelinated axons; 27 Role of Schwann cells in peripheral nerve regeneration; 28 Transplantation of Schwann cells and olfactory ensheathing cells to promote regeneration in the CNS; 29 Trophic factor delivery by gene; 30 Assessment of sensorimotor function after spinal cord injury and repair; Part B4. Translational Research: Application to Human Neural Injury: 31 Alzheimer's disease, model systems and experimental therapeutics; 32 Biomimetic design of neural prostheses; 33 Brain-computer interfaces for communication and control; 34 Status of neural repair clinical trials in brain diseases; Index.
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