The Beta-Adrenergic Receptors / Edition 1

by John P. Perkins

Overview

John Perkins' timely new volume on The Beta-Adrenergic Receptors brings to light the latest information on this key receptor class-the prototype of a family of receptors that regulate the activity of G-proteins. The first of its type to be cloned and sequenced, this receptor class has been the subject of much fruitful study.

The clinical significance of the beta-adrenergic receptors hinges on their usefulness as targets for drugs to control asthma, hypertension, and cardiovascular disease. The Beta-Adrenergic Receptors covers a variety of topics, including: structure-function relationships • ligand-induced desensitization of b-adrenergic receptors • reconstitution of b-adrenergic receptors • biochemical functions • antibodies to b-adrenergic receptors • autoradiographic studies • b-adrenergic receptors in pathophysiological states • clinical applications • drug and hormonal regulation of the b-adrenergic receptor.

The Beta-Adrenergic Receptors is an indispensable resource for biochemists, molecular biologists, pharmacologists, physiologists, neuroscientists, and others involved with the study of receptors at either the research or clinical level.

Product Details

ISBN-13:	9780896031739
Publisher:	Springer-Verlag New York, LLC
Publication date:	06/26/1991
Series:	The Receptors
Edition description:	1991
Pages:	405
Product dimensions:	6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

1 Beta-Adrenergic Receptors: Identification and Characterization by Radioligand Binding Studies.- 2 Structure—Function Relationships.- 3 Mechanisms of Ligand-Induced Desensitization of Beta-Adrenergic Receptors.- 4 Reconstitution of the Beta-Adrenergic Receptor and Its Biochemical Functions.- 5 Antibodies to Beta-Adrenergic Receptors.- 6 Autoradiographic Studies of Beta-Adrenergic Receptors.- 7 Beta-Adrenergic Receptors in Pathophysiologic States and in Clinical Medicine.- 8 Drug and Hormonal Regulation of the Beta-Adrenergic Receptor—Adenylate Cyclase System.

Editorial Reviews

The chapters can be most warmly recommended to all who are active in fundamental and clinical research.-Arzneimittel-Forschung-Drug Research

From the Publisher

A collection of essays that bring to light the latest information on this key receptor class--the prototype of a family of receptors that regulate the activity of G-proteins, the first of its type to be cloned and sequenced. The clinical significance of the beta-adrenergic receptors hinges on their usefulness as targets for drugs to control asthma, hypertension and cardiovascular disease. Topics include: structure-function relationships, biomedical functions, and clinical applications. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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