The Biochemical Basis of Neuropharmacology / Edition 6

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0195071182 Brand NEW Softcover ~ Tight & Bright, meticulously inspected, packed securely, with care and extra padding, and shipped ASAP, we have quick responsive customer service, ... and our feedback score speaks louder than this text, we also ship internationally, and your purchase is always satisfaction guaranteed, Read more Show Less

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In addition to updating each chapter and including a discussion of the new gaseous neuromodulators nitric oxide and carbon monoxide, the authors have made two major changes in this edition. A previous chapter on Metabolism in the Central Nervous System has been eliminated since they feel it has outlived its usefulness. However, some of the material from this chapter has been incorporated into a new chapter on the genetic basis of neurological and psychiatric diseases. With the almost biweekly discovery of genes that appear to be involved in diseases of the nervous system, this area has the potential for providing a revolutionary kind of therapy. The seven editions of this versatile text published over a quarter century attest to its value. It continues to be the first choice wherever courses focus on chemical neurotransmission or basic neuropharmacology: neuroscience courses in medical schools and at the undergraduate level, pharmacy schools, graduate pharmacology programs, and residency programs in psychiatry and neurology.

The book contains black-and-white illustrations.

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Editorial Reviews

Michael Easton
This is the seventh edition of a fundamental text reviewing the neurobiology upon which modem psychopharmacology is based. The purpose of this text is to review the biochemistry and neurophysiology of nervous tissue with a focus on the functions of neurotransmitters. Its intent is to focus on the basic science of the central nervous system and the areas and processes that psychotropics affect. It does not focus on these drugs or medication themselves. This book is intended for individuals interested in neurophysiology and neuropharmacology. It is geared for the postgraduate, physician, or medical resident involved in this area. It will also be valuable to other individuals involved in central nervous system of research or study. The book has an appropriate number of illustrations, tables, and charts. It is well referenced and the authors are experts in this area. This is a highly specialized and technical publication that should be required reading for anyone involved in the field of neuropharmacology. It is a thorough review of neurobiology. It goes over cellular, molecular, receptor and synaptic biology, and neurophysiology. It looks at the various neurotransmitters (monoamines, amino acids, and peptides), along with the mechanisms of learning and memory. It ends by relating this information to the treatment of neurological and psychiatric disorders. The book will provide an excellent foundation for anyone interested in this area.
From the Publisher
From Reviews of Previous Editions:

"Recommended without reservation to students, physicians, and scientists who seek a lucid survey of the biochemical basis of neuronal regulatory systems in the brain."—The New England Journal of Medicine

"The best introductory text available for those who want to learn about the application of biochemical approaches to the study of neurotransmitter and drug actions in the nervous system."—Brain

"This now classic monograph...remains a clear and concise guide...Should be mandatory reading for all medical students, psychiatry residents, graduate students in neuroscience and pharmacology, and is even useful for undergraduate students..."—Contemporary Psychiatry

Doody's Review Service
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is the eighth edition of an outstanding book covering the basics of neurotransmitters, receptors, neurochemical brain systems, and drug action in psychiatric illness. Written and edited by internationally recognized experts in the field, this book continues to be an enormous contribution to education in the neurosciences.
Purpose: The purpose is to present introductory and basic knowledge in neuropharmacology in a clear and concise guide. The editors and chapter authors have continued to succeed in their goal.
Audience: The intended audience is students in medicine, neuroscience, psychology, pharmacology, and residents in psychiatry and neurology. Clinical psychiatrists and neurologists who need to update their knowedge of neuroscience and desire to understand this rapidly growing field, would benefit from reading this book.
Features: The book features 405 pages divided into 13 chapters. The book features coverage of cellular and molecular foundations, receptors, synaptic physiology, the various monoamine systems, neuropeptides, and expanded coverage of cellular mechanisms of learning and memory and the treatment of neurologic and psychiatric disorders. Each chapter ends with useful and up-to-date selected references and there is a helpful index at the back of the book.
Assessment: This valuable book is a standard in neuroscience education and should be part of anyone's essential reading who is interested In the brain and behavior.
From Barnes & Noble
Sections cover Molecular Foundations of Neuropharmacology, Metabolism in the Central Nervous System, Receptors, Amino Acid Transmitters, Acetylcholine, Dopamine, Serotonin & Histamine, Neuroactive Peptides, more.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780195071184
  • Publisher: Oxford University Press, USA
  • Publication date: 9/19/1991
  • Edition description: 6th ed
  • Edition number: 6
  • Pages: 464
  • Product dimensions: 5.50 (w) x 8.19 (h) x 0.84 (d)

Table of Contents

1 Introduction 1
2 Cellular Foundations of Neuropharmacology 7
3 Molecular Foundations of Neuropharmacology 39
4 Receptors 65
5 Modulation of Synaptic Transmission 85
6 Amino Acid Transmitters 105
7 Acetylcholine 151
8 Norepinephrine and Epinephrine 181
9 Dopamine 225
10 Serotonin (5-Hydroxytryptamine), Histamine, and Adenosine 271
11 Neuroactive Peptides 321
12 Cellular Mechanisms in Learning and Memory 357
13 Treating Neurological and Psychiatric Diseases 373
Index 401
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