The Calypso Directive

( 10 )

Overview

An unprecedented genetic mutation, an underground think tank, and an unscrupulous pharmaceutical company collide in this dazzling debut thriller.

For one hundred and fifty-five days, Will Foster has been locked in medical quarantine without his consent. The doctors claim he is infected with a deadly virus, but this is a lie. Encoded in his DNA is a mutation that provides immunity from disease for all who possess it, source code that Vyrogen ...

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The Calypso Directive: A Novel

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Overview

An unprecedented genetic mutation, an underground think tank, and an unscrupulous pharmaceutical company collide in this dazzling debut thriller.

For one hundred and fifty-five days, Will Foster has been locked in medical quarantine without his consent. The doctors claim he is infected with a deadly virus, but this is a lie. Encoded in his DNA is a mutation that provides immunity from disease for all who possess it, source code that Vyrogen Pharmaceuticals aims to commercialize as a multi-billion-dollar gene therapy.

Against all odds, Foster escapes his laboratory prison and steals a virulent strain of bubonic plague as insurance. To help him unravel the mystery inside him, Foster contacts the only person he can trust: a former lover and microbiologist living Vienna and the two become fugitives, hunted across the heart of Europe.

Under the guise of averting a plague pandemic, Vryogen hires an elite, underground Think Tank to track down Foster. But the brilliant team discovers something unexpected—the ugly side of multinational pharmaceutical competition—and must choose between serving their client and saving Foster.

With unflagging suspense, unforgettable characters, and riveting biomedical detail, The Calypso Directive deftly explores the issues of genetic exploitation and piracy. Captivating, controversial, and courageous, Andrews debut is sure to thrill and leave you wondering what secrets are locked in your DNA. 

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  • The Calypso Directive
    The Calypso Directive  

Editorial Reviews

Publishers Weekly
Ponderous prose (“His emotions were a raging river, dragging his mind toward a dangerous cascade”) undermines Andrews’s debut medical thriller. When Will Foster, initially identified only as Patient-65, breaks out of the facility where he’s been held in quarantine for five months, he’s surprised to find himself in Prague, not New York City. Will’s escape sets off alarms at the de rigueur evil drug manufacturing giant, Vyrogen Pharmaceuticals, which has been pursuing an immortality drug in a project named for Calypso, the nymph who offered Odysseus eternal life. Foster reaches out to an old flame, Julie Ponte, for help, and the pair spend the rest of the book dodging thugs in the pay of ruthless Vyrogen executive Meredith Morley. A mysterious Boston think tank is also thrown into the mix, but transcripts of its team members’ communications put the brakes on what little momentum the story line has. Agent: Kristin Lindstrom, Lindstrom Literary Management. (Apr.)
Jopseph Heywood
“Fast-paced and thought-provoking, The Calypso Directive is a dark tale of hubris, and the irrelevance of the individual in a culture driven by science-for-profit and science-for national security. Very believable, conceivable, scary, and real. A rocket-sled ride of a debut by Brian Andrews.”
New York Times Bestselling Author
“A smart, hard-driving thriller. Andrews fires on all cylinders in THE CALYPSO DIRECTIVE.”
Kirkus Reviews
A biological thriller that mixes a series of "what-if" scenarios as it moves from New York to Europe in the blink of an eye. Will Foster, also known as Patient-65, escapes from the prison-like medical facility where he's held captive. Will mounts his escape after weeks of watching the staff and after a few stealthy midnight reconnaissance missions. However, his escape doesn't go as smoothly as he hoped, and soon the young American finds himself in Europe with no idea of exactly where he is or how he got there. After Will was laid off from his job with a New York City-based advertising company, he maxed out his credit cards and job hunted with no success. Based on a friend's advice, Will volunteered as a test subject for some pharmaceutical trials. Soon, he found himself strapped to a hospital bed in Prague and injected with substances he couldn't identify. When Will bolts, his first thought is to look up Julie Ponte, an old love living in Vienna. Although not quite convinced that Will's situation is as desperate as he claims, Julie comes to rescue Will and then takes him back to her apartment, but they soon discover they're being tracked. Meredith Morley, an executive with Vyrogen, the company conducting experiments on Will, launches a team of vicious German brothers who specialize in brutality to hunt for the escaped test subject. But Morley doesn't stop there; she also goes to an old boyfriend for help. He's the genius behind an ultra-high tech, under-the-radar think tank that specializes in doing the impossible. With both sets of trackers on their heels, Will and Julie reestablish their relationship while trying to stay alive and one step ahead of their pursuers. This is an intelligent but technical novel, one that occasionally includes too much scientific detail. The story works until the last third of the novel, when supposedly brilliant and capable people make some pretty basic mistakes that propel the cast of characters into an ending that does little but set up an obvious sequel.
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Product Details

  • ISBN-13: 9781611454949
  • Publisher: Arcade Publishing
  • Publication date: 4/1/2012
  • Pages: 336
  • Product dimensions: 5.90 (w) x 9.10 (h) x 1.20 (d)

Meet the Author

Brian Andrews is a US Navy veteran who served as an officer aboard a 688 class nuclear submarine in the Pacific. He graduated summa cum laude from Vanderbilt University with a degree in psychology. He is a Park Leadership Fellow and holds a Masters in Business Administration from Cornell University’s Johnson School. Brian lives in “Tornado Alley” with his wife and daughter.
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Customer Reviews

Average Rating 5
( 10 )
Rating Distribution

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Sort by: Showing all of 10 Customer Reviews
  • Posted May 2, 2012

    Much better than expected

    Fantastic read - very hard to put down. Great interplay of all the characters and plot lines. Ending leaves room for a sequel. Nice touch with the prequel too. Book reads like a movie and would a great sci-fi-ish action film. Very glad I took a chance on this book.

    3 out of 3 people found this review helpful.

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  • Posted April 26, 2012

    A book I could not put down! Calyplso Directive kept me on the e

    A book I could not put down! Calyplso Directive kept me on the edge of my seat to the end of the book. I can't wait to read Brian Andrews' 'Ring of Flowers' as well! Being a molecular and cellular biology student, I found this book absolutely fascinating as well as entertaining. It will be suggested to staff and students alike throughout the bio department! An amazing story that really makes you think about what could happen as we gain more and more biological information. Recommended for everyone interested in the 'what ifs' of life!

    I won this book on Goodreads First Reads.

    Carrie A. Watson

    3 out of 3 people found this review helpful.

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  • Posted May 23, 2012

    Thrilling Read!

    I loved The Calypso Directive!! It was recommended to me by a friend, and I was not disappointed! I read this book cover-to-cover in a matter of days! The rich plot twists, exciting international chase scenes, and overall pace of the book was gripping! Not only that, but if you're like me and enjoy learning something new --- in this case about the biotechnology world --- you'll love this book. It's obvious that Mr. Andrews did his research. I'm also a bit of a conspiracy theorist and couldn't get enough of the 'The Think Tank' and its operatives---fascinating stuff! I highly recommend The Calypso Directive, and I'm anxiously awaiting Mr. Andrews' next book!

    2 out of 2 people found this review helpful.

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  • Posted April 21, 2012

    An exciting and intelligent page-turning thriller.

    Loved it! A great first novel by a promising new author. Andrews has produced an intelligent page-turning thriller, while creating memorable characters and timely plot twists. I hope there is a series being built around the operatives and futuristic technology of "The Think Tank". As Robin Cook's best seller "Coma" dealt with what was and still is a real-world medical problem, the reaping and selling of human organs, the Calypso Directive is the name given to an effort by agents of an international drug company to steal, patent and commercialize someone's personal genome. I found the author's well-researched medical information about genomes and viruses to be very interesting. I loved the international chase sequence, was fooled by a great final twist at the end and learned something in the process.

    2 out of 2 people found this review helpful.

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  • Posted July 31, 2012

    Refreshingly Fun & Smart

    This was a terrific read and I was very impressed with the perfect balance of pure thrilling entertainment, character development, and subject specific expertise. Because of this, I would strongly agree with the reviewer that mentioned that it reads like a movie! I typically read books in many different genres and this is one of the best reads that I have had in a long time. I am really looking forward to / hoping for a sequel to this book.

    1 out of 1 people found this review helpful.

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  • Posted June 6, 2012

    More than anything else, the Calypso Directive is just a really

    More than anything else, the Calypso Directive is just a really fun read. The action-packed plot -- like the motorcycle chase featured toward the book's close -- revs up fast and keeps the needle in the red till the story's hair-raising conclusion. As the reader, you can't peel your eyes off the page as the psychotic villains and the Think Tank's cohort of uniquely skilled agents (something of an A-Team for intellectuals) close in on Foster, the unlikely "hero" whose special genetic gift has thrust him in the center of a race that pits his own freedom and self-preservation against a pharmaceutical giant's unwavering quest to exploit his "source code" for all it's worth. Who will get to him first? And what will they do with him when and if they do?

    Will Foster is a beguilingly charming hero. He reminds me of Harrison Ford in the Fugitive -- always on the edge of being caught, but somehow, through sheer will to survive combined with an uncanny ability to evade capture that seems to surprise him and the reader both, he manages to stay a step ahead...almost...until all the competing forces converge in an eye-popping, cold-sweat-inducing, electrically charged climax that left me feeling like I was the one dodging bullets and running for my life! Pack this in your beach bag this summer and dive into a first-class adventure.

    1 out of 1 people found this review helpful.

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  • Posted May 10, 2013

    more from this reviewer

    Brian Andrews in his new book, "The Calypso Directive"

    Brian Andrews in his new book, "The Calypso Directive" published by Arcade Publishing brings us into the life of Will Foster.

    From the back cover: An unprecedented genetic mutation, an underground think tank, and an unscrupulous pharmaceutical company collide in this dazzling debut thriller.

    For one hundred and fifty-five days, Will Foster has been locked in medical quarantine without his consent. The doctors claim he is infected with a deadly virus, but this is a lie. Encoded in his DNA is a mutation that provides immunity from disease for all who possess it, source code that Vyrogen Pharmaceuticals aims to commercialize as a multi-billion dollar gene therapy.

    Against all odds, Foster escapes his laboratory prison and steals a virulent strain of bubonic plague as insurance. To help him unravel the mystery inside him, Foster contacts the only person he can trust-a former lover and microbiologist living in Vienna- and the two become fugitives, hunted across the heart of Europe.

    Under the guise of averting a plague pandemic, Vryogen hires an elite, underground Think Tank to track down Foster. But when the team sets a trap for Foster, they discover they're not the only ones in the hunt. In a race against two deadly assassins, can the brilliant minds of the Think Tank unravel the truth before time runs out for their quarry?

    In a novel where conscience clashes with greed, loyalty with suspicion, and paranoia with reality, THE CALYPSO DIRECTIVE deftly explores the issues of genetic exploitation and piracy. Captivating, controversial, and courageous, Andrews debut is sure to thrill and leave you wondering what secrets are locked in your DNA.

    I have to admit I just enjoy to no end these kind of thrillers where the hero is on the run pursued by a bunch of killers who sole objective is his elimination. Brian Andrews has pumped up the plot even more as Will Foster has a sample of bubonic plague that he will use before he is killed. Paranoia increases when Vryogen, who has their killer on the hunt, hires The Think Tank to send another killer after Will. Now the chase is on across Europe and all Will wants to do is stay alive. "The Calypso Directive" is a riveting, page-turning thriller as the life of Will Foster is in deadly danger practically from page one. Mr. Andrews packs in a huge amount of action, adventure, and suspense as Foster tries to figure out a way to turn the tables on his pursuers and bring down the company that is trying to kill him. May I never get myself into this kind of situation because I could never get out. Good thing Mr. Andrews could figure out the way out and give us a wild ride while getting there. Give yourself plenty of time to enjoy this book as you will want to finish it before going to bed. "The Calypso Directive" is an exciting adventure from start to finish.

    Disclosure of Material Connection: I received this book free from the author. I was not required to write a positive review. The opinions I have expressed are my own. I am disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials in Advertising."

    Was this review helpful? Yes  No   Report this review
  • Posted January 5, 2013

    Fascinating plot involving human biological experimentation and

    Fascinating plot involving human biological experimentation and the crossroads of biotechnology and ethics. It's so timely and relevant given the US Supreme Court has agreed to consider in the 2012-2013 term how patent existing rules apply to self-replicating technologies. In fact, this case may affect patents on other cutting-edge technologies, including man-made cell lines, DNA molecules, nanotechnologies and organic computers.
    So The Calypso Directive is not just an arresting reading where the Prague's escape makes Grisham's "The Firm" a mere stroll in Memphis riverfront, but also a contemporary theme in which our civilization will reckon with for centuries to come.

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  • Anonymous

    Posted May 2, 2012

    No text was provided for this review.

  • Anonymous

    Posted April 24, 2012

    No text was provided for this review.

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