The Chemokines

by I.J.D. Lindley (Editor), J. Westwick (Editor), S. Kunkel (Editor)

Overview

Symposium Presentations.- Chemotactic and Inflammatory Cytokines: CXC and CC Proteins.- Induction of Chemotactic Cytokines by Minimally Oxidized LDL.- The Immunopathology of Chemotactic Cytokines.- Receptor/ligand Interactions in the C-C Chemokine Family.- Adhesion Molecules in Acute and Chronic Lung Inflammation.- Monocyte Chemotactic Protein-1 (MCP-1): Signal Transduction and Involvement in the Regulation of Macrophage Traffic in Normal and Neoplastic Tissues.- Secretion of Monocyte Chemoattractant Protein-1 (MCP-1) by Human Mononuclear Phagocytes.- L-arginine/nitric Oxide Pathway: A Possible Signal Transduction Mechanism for the Regulation of the Chemokine IL-8 in Human Mesangial Cells.- Some Aspects of NAP-1/IL-8 Pathophysiology II: Chemokine Secretion by Exocrine Glands.- Molecular Mechanisms of Interleukin-8 Gene Expression.- Basophil Activation by Members of the Chemokine Superfamily.- Monocyte Chemotactic Proteins Related to Human MCP-1.- Platelets Secrete an Eosinophil-chemotactic Cytokine which is a Member of the CC Chemokine Family.- Neutrophil-activating Peptide ENA-78.- The Effects of Human Recombinant MIP-1?, MIP-1? and RANTES on the Chemotaxis and Adhesion of T Cell Subsets.- Promiscuity of Ligand Binding in the Human Chemokine Beta Receptor Family.- Structural and Functional Characterization of the Interleukin-8 Receptors.- Elucidation of Structure Function Relationships in the IL-8 Family by X-ray Crystallography.- Overview of Chemokines.- Abstracts.- Regulation of Cytokine Secretion by Poxvirus Encoded Proteins.- Interleukin-8 Expression in Gastric Cancer.- Synergistic IL-8 Synthesis by Human Peritoneal Mesothelial Cells (HPMC) Following IL-1? and TNF? Treatment.- Detection of a Potent Chemotactic Activity in Supernatants from Human Monocytes Stimulated with Endothelin-1.- Glioblastoma Secrete MCP-1, a Monocyte Chemotactic Factor.- Neutrophil Chemotactic Activity in the Bronchoalveolar Lavage Fluid of Asthmatics.- The Chemoattractant Properties of Interleukin-4.- IL-8 Induced Chemotaxis of Peripheral Neutrophils in Children with Cystic Fibrosis (CF).- Unusual Properties in Vitro and in Vivo of 198, an Antibody that Recognizes Rabbit CD11b.- Effect of Monocyte Chemotactic Cytokine Gene Transfer on Macrophage Infiltration, Growth and Metastatic Behaviour of a Murine Melanoma.- Expression of Monocyte Protein 1 (MCP-1) by Monocytes and Endothelial Cells Exposed to Thrombin.- IL-8 Production During Urinary Tract Infections.- NAP-1/IL-8 Receptor Expression on Human Neutrophils.- Macrophage-derived Neutrophil Chemotactic Factor (MNCF) Induces Neutrophil Migration Through Lectin-like Activity.- Interleukin-8 Release from Human PMN is Modified by Airborne Particulated Matter.- Interleukin-8 Induces the Expression of HLA-DR Antigen on Human Keratinocytes.- Cloning, Sequencing and Expression of Ovine Neutrophil-attractant Protein-1/IL-8 and Monocyte Chemoattractant Protein-1.- Inhibition of LPS-mediated Responses in Human Whole Blood by Recombinant Bactericidal/Permeability Increasing Protein.- The Activity of IL-8 in Combination with GMCSF and TNF?.- Induction of IL-8 in Inflammatory Bowel Disease.- Elevated Circulating and Tissue IL-8 in Alcoholic Hepatitis.- Expression of Monocyte Chemoattractant Protein-1 in Basal Keratinocytes of Psoriatic Lesions.- IL-8 Concentration in ?-Thalassaemia and after Bone Marrow Transplantation.- Cytokine Production in Felty's Syndrome.- The Lymphocyte Attractant Effects of Interleukins la and 8 Are Not Due to the Release of a Secondary Chemoattractant Factor.- Serial Changes in Circulating Interleukin-8 and Neutrophil Elastase After Major Surgery.- Role of Interleukin-8 in the Pathogenesis of Neutrophil-mediated Acute Lung Injury.- Interleukin-8 in Severe Meningococcal Infections: Correlation with Severity of Disease.- IL-6 and IL-8 Levels in Patients with Rheumatoid Arthritis.- Plasma Interleukin 8 Levels in Patients with Septic Shock.- Inhibitory Effect of Protease-inhibitor for P...

Product Details

ISBN-13:	9780306447105
Publisher:	Springer-Verlag New York, LLC
Publication date:	06/28/1994
Series:	Advances in Experimental Medicine and Biology Series , #351
Edition description:	New Edition
Pages:	244
Product dimensions:	7.09(w) x 10.63(h) x (d)

Editorial Reviews

Proceedings of the Third International Symposium on Chemotactic Cytokines (identified by consensus at the symposium as "chemokines," to replace all previous terms), held in Baden bei Wien, Austria, Aug.- Sept. 1992. The chemokines are involved in recruitment and activation of specific immune cells and regulation of adhesion molecules on the cell surface, and have been implicated in many disease states, including atherosclerosis, asthma, renal disease, rheumatoid arthritis, psoriasis, and allergy. New findings in the area involve cloning of new members of the family, new activities of known members, and cloning of specific receptors, in addition to new clinical and experimental data. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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