The Comatose Patient


The Comatose Patient, Second Edition, is a critical historical overview of the concepts of consciousness and unconsciousness, covering all aspects of coma within 100 detailed case vignettes. This comprehensive text includes principles of neurologic examination of comatose patients as well as instruction of the FOUR Score coma scale, and also discusses landmark legal cases and ethical problems. As the Chair of Division of Critical Care Neurology at Mayo Clinic, Dr. Wijdicks uses his extensive knowledge to discuss ...

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The Comatose Patient

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The Comatose Patient, Second Edition, is a critical historical overview of the concepts of consciousness and unconsciousness, covering all aspects of coma within 100 detailed case vignettes. This comprehensive text includes principles of neurologic examination of comatose patients as well as instruction of the FOUR Score coma scale, and also discusses landmark legal cases and ethical problems. As the Chair of Division of Critical Care Neurology at Mayo Clinic, Dr. Wijdicks uses his extensive knowledge to discuss a new practical multistep approach to the diagnosis of the comatose patient. Additionally, this edition includes extensive coverage of the interpretation of neuroimaging and its role in daily practice and decision making, as well as management in the emergency room and ICU. Dr. Wijdicks details long-term supportive care and an appropriate approach to communication with family members about end-of-life decision making.

In addition, video clips on neurologic examination and neurologic manifestations seen in comatose patients can be found here: All video recordings from the first edition have been reformatted and remastered for optimal use, and several more video clips of patients have also been included.

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Editorial Reviews

From the Publisher
"The first edition of Wijdicks' The Comatose Patient brought the discussion of coma to the 21st Century, covering not only pathophysiology and diagnostics but also treatment. The 2nd edition of this comprehensive treatise employs a modern, highly effective format including 100 case descriptions on causes of coma, well organized tables and reformatted videos. There are updated and expanded sections on EEG monitoring, neurorehabilitation and functional MRI as well as new sections on the historical development of prognostication in coma and common problems evaluating coma in the emergency department. The 2nd edition of The Comatose Patient is another outstanding effort by this prolific world authority on coma and a must read for all neurointensivists." —Michael N. Diringer, MD, Professor of Neurology, Neurosurgery & Anesthesiology
Chief, Neurocritical Care Section, Washington University School of Medicine
St. Louis, MO

"Wijdicks has taken his usual original approach to the difficult subject of coma. The book is a refreshing change from the codified and stodgy structure of most texts on a single subject. By giving a thorough introduction to the subject of coma that is peppered with his own experiences, and following this by brief vignette-like and highly focused chapters on coma in specific diseases, a new approach is opened up for clinical work. It is a pleasure to read a book that flows and is instructive but can also be used for a reference source in complicated clinical situations." —Allan Ropper, MD, Brigham and Women's Hospital, Department of Neurology, Boston, MA

"These days, with infinite amounts of medical information at your fingertips on the internet, one might wonder why medical textbooks are necessary any more. The Comatose Patient, 2nd Edition, by master clinician-scholar Eelco Wijdicks, is the reason why. Authoritative and comprehensive, this gorgeous book covers possible every aspect of coma, including its history, pathophysiology, treatment, outcome, and impact on society at large. Coma is a direct consequence of our efforts to fight death. Nowhere else will you find this level of insight into a medical syndrome that has always fascinated and will increasingly challenge humanity." —Stephan A. Mayer, MD, Professor of Neurology and Neurosurgery
Director, Institute for Critical Care Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

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Product Details

  • ISBN-13: 9780199331215
  • Publisher: Oxford University Press
  • Publication date: 5/26/2014
  • Edition number: 2
  • Pages: 808
  • Product dimensions: 7.10 (w) x 10.20 (h) x 1.80 (d)

Meet the Author

Professor of Neurology
Mayo Clinic College of Medicine
Chair, Division of Critical Care Neurology
Consultant, Neurosciences Intensive Care Unit
Saint Marys Hospital
Mayo Clinic, Rochester, MN

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Table of Contents

Preface to the Second edition
Preface to the First edition
Part I: Understanding, Diagnosing, and Care of Comatose States
1. A History of Coma: Evolution of Ideas
2. The Neuroscience of the Awake State
3. Neurological Examination of the Comatose Patient and Localization Principles
4. Prolonged Impaired Consciousness
5. Brain Death
6. Neuroimaging, Neurophysiology and Neuropathology
7. Clinical Diagnosis and Decisions
8. Medical Care of the Comatose Patient
9. Recovery and Rehabilitation
10. Law and Bioethics
11. Media and popular culture
Part II: The Clinical Approach to the Comatose Patient in 100 Vignettes
12 Introduction to 100 Clinical Vignettes
13 Comatose and traumatic brain injury
14 Comatose and gunshot wound to the brain
15 Comatose and traumatic brainstem lesion
16 Comatose after shaken impact syndrome
17 Comatose and acute epidural hematoma
18 Comatose and acute subdural hematoma
19 Comatose after cerebral hematoma
20 Comatose and intraventricular hemorrhage
21 Comatose and pontine hemorrhage
22 Comatose and cerebellar hemorrhage
23 Comatose and aneurysmal subarachnoid hemorrhage
24 Comatose and cerebral venous thrombosis
25 Comatose and hemispheric stroke
26 Comatose and bihemispheric stroke
27 Comatose and basilar artery occlusion
28 Comatose and bacterial meningitis
29 Comatose and brain abscess
30 Comatose and empyema
31 Comatose and acute herpes simplex encephalitis
32 Comatose and H1N1 influenza
33 Comatose and rabies encephalitis
34 Comatose and mumps encephalitis
35 Comatose and acute necrotic encephalitis
36 Comatose and zoonotic disease
37 Comatose and neuroaspergillosis
38 Comatose and nocardiosis
39 Comatose and high-grade astrocytoma
40 Comatose and CNS lymphoma
41 Comatose and metastasis
42 Comatose and gliomatosis
43 Comatose and paraneoplastic limbic-encephalitis
44 Comatose and autoimmune encephalitis
45 Comatose and acute disseminated encephalomyelitis
46 Comatose and fulminant multiple sclerosis
47 Comatose and osmotic demyelination
48 Comatose and acute hydrocephalus
49 Comatose and CSF hypotension
50 Comatose and convulsive status epilepticus
51 Comatose and nonconvulsive status epilepticus
52 Comatose in the recovery room
53 Comatose after organ transplantation
54 Comatose after coronary artery bypass surgery
55 Comatose on ECMO
56 Comatose after brain biopsy and craniotomy
57 Comatose and epilepsy surgery
58 Comatose after cerebral angiogram
59 Comatose after clipping of a ruptured cerebral aneurysm
60 Comatose after endovascular treatment of ruptured cerebral aneurysm
61 Comatose and hypothermia
62 Comatose and CO inhalation
63 Comatose and heatstroke
64 Comatose and near drowning
65 Comatose after cardiopulmonary resuscitation
66 Comatose after therapeutic hypothermia
67 Comatose after near hanging
68 Comatose after fat embolism syndrome
69 Comatose and air embolism
70 Comatose after status asthmaticus
71 Comatose and acute uremia
72 Comatose and acute hypertensive crises
73 Comatose and fulminant hepatic failure
74 Comatose and chronic liver disease
75 Comatose and thyroid disease
76 Comatose and sepsis
77 Comatose and endocarditis
78 Comatose after aorta dissection
79 Comatose and hypoglycemia
80 Comatose and hyperglycemia
81 Comatose and hyponatremia
82 Comatose and hypernatremia
83 Comatose and hypercalcemic crises
84 Comatose and hypercapnia
85 Comatose and pituitary apoplexy
86 Comatose and systemic lupus erythematosus
87 Comatose and central nervous system vasculitis
88 Comatose and acute thrombocytopenia
89 Comatose and acute leukemia
90 Comatose and acute porphyria
91 Comatose and urea cycle disorder
92 Comatose and Wernicke-Korsakoff Syndrome
93 Comatose and MELAS
94 Comatose and premature newborn
95 Comatose and fulminant cerebral vasoconstriction
96 Comatose and puerperium
97 Comatose and chemotherapy toxicity
98 Comatose and intrathecal baclofen overdose
99 Comatose and cefepime toxicity
100 Comatose and acetaminophen overdose
101 Comatose and tricyclic antidepressant overdose
102 Comatose and SSRI overdose
103 Comatose and alcohol intoxication
104 Comatose and ethylene glycol ingestion
105 Comatose and salicylate overdose
106 Comatose and opioid overdose
107 Comatose and benzodiazepine overdose
108 Comatose and lithium toxicity
109 Comatose after a rave party
110 Comatose and rapid dementing illness
111 Comatose and malignant catatonia
112 Comatose and conversion disorder

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