The Dynamic Genome and Mental Health: The Role of Genes and Environments in Youth Development

The Dynamic Genome and Mental Health: The Role of Genes and Environments in Youth Development

by Kenneth S. Kendler
     
 

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While it is widely accepted that we are products of our genes and environment, misconceptions about the power of genes to control our destiny continue to dominate our discourse. This volume contains the latest theories and evidence supporting the highly dynamic inter-relation between genes and environments as they influence the development, mental health, and

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Overview

While it is widely accepted that we are products of our genes and environment, misconceptions about the power of genes to control our destiny continue to dominate our discourse. This volume contains the latest theories and evidence supporting the highly dynamic inter-relation between genes and environments as they influence the development, mental health, and substance use of adolescents. Written by researchers who are leading the way toward this new understanding, this text provides overviews and analysis of this emerging field. The chapters discuss the latest approaches to gene-environment relations, including gene-environment interaction, gene-environment correlation, epigenetics, and environmental regulation of gene expression. The application of these concepts to the prevention of adolescent mental health conditions, such as drug use, conduct disorder, depression, and schizophrenia, is included. Controversies in the implications of these approaches are also discussed.

The chapters are written in accessible language and will relevant to anyone interested in the mental health and development of adolescents, including researchers and practitioners in behavioral, social and medical fields. A final chapter by the editors assesses the implications of these new approaches for future mental health research and policy.

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Editorial Reviews

Doody's Review Service
Reviewer: Michael Joel Schrift, DO, MA (University of Illinois at Chicago College of Medicine)
Description: The promise of genetic research in psychiatry is the understanding of how genes and the environment affect behavior through changing the human brain. This book presents a critical review of the evidence for genetic and environmental contributions to common psychiatric conditions emphasizing the genetic control of sensitivity to the environment as well as genetic control of exposure to the environment. This outstanding new book, edited and authored by internationally renowned individuals in this field, is a welcome addition to this rapidly emerging area.
Purpose: The purpose, according to the editors, is to present three major themes to the reader: gene-environment interaction, gene-environment correlation, and development. The editors want to emphasize "the old static views about genetic and environmental contributions to behavioral and psychiatric traits do not accurately depict reality;" "genes and the environment cannot be studied in isolation from one another;" and "the idea that genes are static and stable in their effect across the lifespan...is just plain wrong."
Audience: The intended audience is psychiatrists and geneticists and the book will be of interest to neurologists, psychologists, and neuroscientists.
Features: Part 1 is an overview of gene-environment interplay, specifically focusing on gene-environment interaction and correlation in the context of development. Part 2 reviews gene and environmental contributions to depression and anxiety, substance abuse, and stress and schizophrenia. Part 3 concludes the book with a brilliant chapter on the scientific, ethical, and policy implications of the research on gene-environment interactions. Each chapter ends with up-to-date and pertinent citations of the scientific literature.
Assessment: This book ought to be required reading for anyone interested in keeping up with the science attempting to understand how genes and the environment affect the brain and behavior.
From the Publisher
"This book ought to be required reading for anyone interested in keeping up with the science attempting to understand how genes and the environment affect the brain and behavior." — Doody's

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Product Details

ISBN-13:
9780199737963
Publisher:
Oxford University Press, USA
Publication date:
04/29/2011
Edition description:
New Edition
Pages:
480
Product dimensions:
6.10(w) x 9.20(h) x 1.00(d)

Meet the Author

Kenneth S. Kendler, MD, is Professor of Psychiatry and Human and Molecular Genetics at Virginia Commonwealth University and Director of the Virginia Institute for Psychiatric and Behavioral Genetics

Sarah Jaffee, PhD, is a Developmental Psychopathologist at Kings College, London

Daniel Romer, PhD, is Dan Romer is director of the Adolescent Communication Institute (ACI) of the Annenberg Public Policy Center at the University of Pennsylvania

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