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The Endothelium in Cardiovascular Disease: Pathophysiology, Clinical Presentation, and Pharmacology

Overview

The endothelium plays an important role in the pathophysiology of the circulatory system. The reader's attention therefore is directed towards the possible involvement of these polypeptides in the aetiology of ischaemic heart disease, cerebrovascular accidents, hypertension, atherosclerosis and renal failure.

The book contains black-and-white illustrations.

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Germany 1995 Hardcover One Corner lightly Bumped Very Good Ex-Library Cond Book 8vo-over 7?"-9?" tall 197 pgs. Blue/black boards with white lettering. Usual library markings. ... Clean and tightly bound. Read more Show Less

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Overview

The endothelium plays an important role in the pathophysiology of the circulatory system. The reader's attention therefore is directed towards the possible involvement of these polypeptides in the aetiology of ischaemic heart disease, cerebrovascular accidents, hypertension, atherosclerosis and renal failure.

The book contains black-and-white illustrations.

Read More Show Less

Product Details

  • ISBN-13: 9783540593522
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 1/1/1995
  • Edition number: 1
  • Pages: 197

Table of Contents

The Endothelium as a Regulator of Vascular Tone and Growth 1
Effects of Physical and Pharmacological Interventions on Circulating Endothelin-1 Levels in Humans 25
The Role of Endothelin in Congestive Heart Failure 33
Endothelin as a Regulator of Vascular Tone in Man: Studies in Upper Limb Resistance and Capacitance Vessels 43
Systemic and Endocrine Effects of Endothelin in Humans 57
Endothelin in Hypertension and Vascular Hypertrophy: Experimental Studies 66
Role of Endogenous Endothelin in Myocardial Ischemia and Nitric Oxide-Deficient Hypertension 74
Endothelin and Renal Function: From Theory to Therapy 84
The Endothelium and the Pathogenesis of Chronic Vascular Diseases: The Protective Role of Calcium Antagonists 97
Insulin and the Regulation of the Cardiovascular System: Role of the L-arginine Nitric Oxide Pathway and the Sympathetic Nervous System 108
Endothelin Receptor Antagonists as New Tools to Inhibit Endothelin induced Vasoconstriction in Humans: Comparison with Calcium Channel Blockers 129
Endothelial Dysfunction: Clinical Applicability of Calcium Antagonist Drugs 148
Endothelin in Hypertension and Diabetes Mellitus 157
Endothelium-Dependent Vasodilation in the Peripheral Circulation in Humans In Vivo: Effects of Hypertension and Aging 171
Endothelin and Pulmonary Hypertension 184
Subject Index 195
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