The Flaviviruses: Detection, Diagnosis and Vaccine Development

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Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.

Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and ...

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The Flaviviruses: Detection, Diagnosis and Vaccine Development: Detection, Diagnosis and Vaccine Development

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Overview

Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.

Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research.

• Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions
• Descibes the technologies that have contributed to our current knowledge about the Flaviviruses
• Identifies the major problems faced in understanding the virus-host interactins that result in disease
• An exhaustive compendium of current and past knowledge on the Flavivirus family

Audience: Virologists, molecular epidemiologists, clinicians and public health specialists, immunologists, and researchers in vaccine development.

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Editorial Reviews

From the Publisher
"...an essential series of books that belongs on every arbovirologists’ bookshelf."
-Stephen Higgs, Ph.D., University of Texas Medical Branch, U.S. (2004)
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Product Details

  • ISBN-13: 9780120398614
  • Publisher: Elsevier Science
  • Publication date: 1/2/2004
  • Series: Advances in Virus Research Series
  • Pages: 577
  • Product dimensions: 6.20 (w) x 9.20 (h) x 1.08 (d)

Table of Contents

Diagnosis and Surveillance
Serodiagnosis of Flaviviral Infections and Vaccinations in Humans
Molecular amplification assays for the detection of Flaviviruses
Virus Epidemiology, Ecology and Emergence
Japanese Encephalitis
Epidemiology of St Louis encephalitis virus
West Nile Virus: epidemiology and Ecology in North America
Dengue Epidemiology: Virus Epidemiology, Ecology and Emergence.
Epidemiology and Ecology of Yellow Fever virus
Virus Epidemiology, Ecology and Emergence of Tick-borne flaviviruses
Vaccines and Antiviral Agents
Formalin-inactivated whole virus and recombinant subunit flavivirus vaccines
Empirically derived live, attenuated vaccines against Dengue and Japanese Encephalitis
DNA vaccines for Flaviviruses
Chimeric Flaviviruses: novel vaccines against dengue fever, tick-borne encephalitis and Japanese encephalitis
Prospects for antiviral therapy

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