The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation / Edition 1

The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation / Edition 1

by Gajanan V. Sherbet, M. S. Lakshmi
     
 

An understanding of the genetic basis of cancer and the mechanisms governing cancer invasion and its secondary spread are fundamental to our ability to design appropriate treatments.
This book, written by internationally recognised experts in cancer biology, provides insights into the deregulation of the cell cycle in tumour development and integrates the

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Overview

An understanding of the genetic basis of cancer and the mechanisms governing cancer invasion and its secondary spread are fundamental to our ability to design appropriate treatments.
This book, written by internationally recognised experts in cancer biology, provides insights into the deregulation of the cell cycle in tumour development and integrates the function of tumour suppressor genes, oncogenes and metastasis-associated genes in the pathogenesis and progression of cancer.
This volume presents an up to date and comprehensive coverage of current research in the field.
The contents include:
• Clonal evolution of the metastasis phenotype
• Cell Cycle regulation
• Apoptosis in tumour growth and metastasis
• Angiogenesis in cancer
• Cell surface glycoproteins and their receptors
• Proteinases and their inhibitors in cancer invasion
• Oncogenes and cancer metastasis
• Developmental genes
• Tumour suppressor genes
• Metastasis suppressor genes
• Dominant metastasis-associated genes
This book will be of interest to all graduates, clinicians and researchers working in the fields of cancer biology, genetics and molecular biology.

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Product Details

ISBN-13:
9780126398755
Publisher:
Elsevier Science
Publication date:
07/11/1997
Pages:
338
Product dimensions:
0.88(w) x 6.14(h) x 9.21(d)

Table of Contents

Preface.
Acknowledgement.
Introduction.
Clonal Evolution of Metastasis.
Inefficiency of the Metastatic Process.
Tumor Growth and Metastatic Potential.
Cell Cycle Regulation and Metastasis.
Apoptosis in Tumor Growth and Metastasis.
Angiogenesis in Cancer.
Cell Surface Glycoproteins and Their Receptors.
Proteinases and Their Inhibitors in Cancer Invasion.
Oncogenes and Cancer Metastasis.
Developmental Genes and Their Putative Tumor Suppressor Function.
Tumor Suppressor Genes.
Metastasis Suppressor Genes.
Dominant Metastasis Associated Genes.
Epilogue.
References.

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