The Handbook of Plant Metabolomics

Overview

Metabolomics is the analysis of all metabolites such as metabolic intermediates, hormones and so on, in a given system such as a cell, an organ or a whole organism. It is complementary to the genomics and proteomic analysis of a system and an essential building block towards the understanding of a whole biological system. Being a relatively new approach, a number of techniques have been recently developed in order to experimentally analyse metabolites and many researchers are expanding into this field. Knowledge ...

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Overview

Metabolomics is the analysis of all metabolites such as metabolic intermediates, hormones and so on, in a given system such as a cell, an organ or a whole organism. It is complementary to the genomics and proteomic analysis of a system and an essential building block towards the understanding of a whole biological system. Being a relatively new approach, a number of techniques have been recently developed in order to experimentally analyse metabolites and many researchers are expanding into this field. Knowledge about the metabolic status of a system is critical for its comprehensive understanding and metobolomics is an important tool for systems biologists.

This is the newest title in the successful Molecular Plant Biology Handbook Series. Just like the other titles in the series, The Handbook of Plant Metabolomics presents an excellent overview of different approaches and techniques in the subject. Contributors are either from ivy-league research institutions or from companies developing new technologies in this dynamic and fast-growing field. With its approach to introduce current techniques in plant metabolomics to a wider audience and with many labs and companies considering to introduce metabolomics for their research, this book is intended for molecular biologists, geneticists, biotechnologists, plant physiologists, gene technologists, protein chemists, biotechnological industry personel and the pharmaceutical industry.

With uniform chapter design with summaries and comprehensive glossary, the Kahl books are in addition a trusted brand for the plant science community.

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Product Details

  • ISBN-13: 9783527327775
  • Publisher: Wiley
  • Publication date: 4/22/2013
  • Series: Molecular Plant Biology Series
  • Edition number: 1
  • Pages: 448
  • Product dimensions: 6.90 (w) x 9.70 (h) x 0.60 (d)

Meet the Author

Günter Kahl is Professor for Plant Molecular Biology at the Biocenter of Johann Wolfgang Goethe-University of Frankfurt/Main, Germany. After gaining his PhD in plant biochemistry, he spent two postdoctoral years at Michigan State University, East Lansing, USA, joining Professor Joe Varner, and at the California Institute of Technology, Pasadena, California, with Professor James Bonner. His main research interests are:
- Sequencing and analysis of fungal, plant and animal genomes
- Transcriptome analysis in pro- and eukaryotic organisms
- Technology development
Günter Kahl is the author of more than 250 scientific journal publications and several book publications including all titles of the successful Molecular Plant Biology Handbook series, and currently holds the CSO position at GenXPro GmbH, a company specializing in novel technologies in genomics and transcriptomics, located at the Frankfurt Innovation Centre for Biotechnology (FIZ), Frankfurt/Main, Germany.

Wolfram Weckwerth is Professor and founding chair of the Department of Molecular Systems Biology (MOSYS) at the University of Vienna, Austria. He holds a diploma in chemistry and a PhD in biochemistry, both from the Technical University Berlin, Germany. His main research interests are:
- The development of genome-wide metabolomics and proteomics/phosphoproteomics technologies as elementary systems biology techniques, high throughput profiling (HTP) in systems biology, data integration; combining experimental approaches with multivariate statistics, pattern recognition, modeling of metabolism, and functional genome interpretation: synergetics
- The genotype-environment-phenotype-equation: plant ecology and phenotypic plasticity including stress, growth, developmental and nutritional physiology
- Plant-microbe-interaction and medicinal plants
- Green Systems Biology: application of systems biology approaches in ecology, evolution and biotechnology

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Table of Contents

Preface
CENTRAL METABOLISM
Metabolic profiling of plants by GC-MS (Camilla B. Hill, Ute Roessner)
Isotopologue profiling: towards a better understanding of metabolic pathways (Wolfgang Eisenreich, Claudia Huber, Erika Kutzner, Nihat Knispel, Nicholas Schramek)
Nuclear magnetic resonance spectroscopy for plant metabolite profiling (Sonia van der Sar, Hye Kyong Kim, Axel Meissner, Robert Verpoorte, Young Hae Choi)
Comprehensive two-dimensional gas chromatography for metabolomics (Katja Dettmer, Martin F. Almstetter, Christian J. Wachsmuth and Peter J. Oefner)
MALDI mass spectrometric imaging of plants (Ales Svatos, Hans-Peter Mock)
Medicago truncatula root and shoot Metabolomics: Protocol for the investigation of the primary carbon and nitrogen metabolism based on GC-MS (Vlora Mehmeti, Lena Fragner, Stefanie Wienkoop)

SECONDARY AND LIPID METABOLISM
Study of the volatile metabolome in plant-insect interactions (Georg J.F. Weingart, Nora C. Lawo, Astrid Forneck, Rudolf Krska, Rainer Schuhmacher)
Metabolomics in Herbal Medicine Research (Lie-Fen Shyur, Chiu-Ping Liu, Shih-Chang Chien)
Integrative analysis of secondary metabolism and transcript regulation in Arabidopsis Thaliana (Fumio Matsuda, Kazuki Saito)
Liquid chromatography mass spectrometry analysis of flavonoids (Maciej Stobiecki, Piotr Kachlicki)
GC/MS based lipidomics (Takeshi Furuhashi, Wolfram Weckwerth)
Multi-gene transformation for pathway engineering of secondary metabolites (Hideyuki Suzuki, Eiji Takita, Kiyoshi Ohyama, Satoru Sawai, Hikaru Seki, Nozomu Sakurai, Toshiya Muranaka, Masao Ishimoto, Hiroshi Sudo, Kazuki Saito, Daisuke Shibata)

METABOLOMICS AND GENOMICS
Metabolomics Assisted Plant Breeding (Alexander Herrmann, Nicolas Schauer)
Conducting Genome Wide Association Mapping of Metabolites (Susanna Atwell, Daniel J. Kliebenstein)

METABOLOMICS AND BIOINFORMATICS
Metabolite clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps (Alexander Kaever, Manuel Landesfeind, Kirstin Feussner, Ivo Feussner, Peter Meinicke)
Metabolite identification and computational mass spectrometry (Steffen Neumann, Florian Rasche, Sebastian Wolf, Sebastian Böcker)
COVAIN - a metabolomics data mining toolbox (Xiaoliang Sun, Wolfram Weckwerth)
Mass Spectral Search and Analysis using the Golm Metabolome Database (Jan Hummel, Nadine Strehmel, Christian Bölling, Stefanie Schmidt, Dirk Walther, Joachim Kopka)

Glossary
Index

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