The Interface of Sleep Medicine and Movement Disorders / Edition 1

Hardcover (Print)
Not Available on

More About This Textbook


Sleep, Movement Disorders, and Dopamine will be divided into five parts, each detailing a unique theme: (I) physiology of the dopaminergic system; (II) role of DA in PLMD and RLS; (III) DA hypofunction as a contributor to RBD; (IV) imaging studies in DA deficient states; and finally (V) the downside of DA treatment underlying the fine balance between sleep and wakefulness. Each part will be divided into several chapters further exploring and reviewing recent data as detailed in the table of contents.

Read More Show Less

Product Details

Table of Contents

Table of Contents:

Preface: Sleep, Movement Disorders, and Dopamine

Alon Avidan MD, MPH

Part I: Role of Dopamine in Sleep and Wakefulness

Chapter 1: Neurobiology of Dopaminergic Modulation of Behavioral States.

Contributor: Alon Y. Avidan MD, MPH, Department of Neurology, UCLA.

Chapter 2: The Two Faces of Eve: Dopamine's Modulation of Wakefulness and Sleep, Emerging Views from an Unlikely Source: Parkinson’s disease.

Contributor/s: D. B. Rye and J. Jankovic, Department of Neurology, Emory University.

Part II: The Role of Dopamine in Restless Leg Syndrome, Periodic Leg Movements and Alternating Leg Muscle Activation

Chapter 3: Restless Legs Syndrome: Revisiting the Dopamine Hypothesis from the Spinal Cord Perspective.

Contributor/s: Paulus W, Schomburg ED. Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Str. 40, 37075 Gottingen, Germany.

Chapter 4: Parkinson’s Disease and Restless Legs Syndrome: A Dopaminergic Bridge

Contributor/s: Earley CJ, Hyland K, Allen RP. Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA.

Chapter 5: Treatment of Restless Legs Syndrome with Dopamine Agonists. The Benefits.

Contributor: Karin Stiasny-Kolster, MD, Department of Neurology, Center of Nervous Diseases, Rudolf-Bultmann-Strasse 8, D-35033 Marburg, Germany


Chapter 6: Dopamine D2 Receptor Alteration in Patients with Periodic leg Movements.

Contributor/s: J. Staedt. Department of Psychiatry, Georg August University, Göttingen, Federal Republic of Germany

Chapter 7: The Neurophysiology of the Alternating Leg Muscle Activation (ALMA) during sleep: Why Do Dopamine Agonists Help?

Contributor/s: Cosentino FI, Iero I, Lanuzza B, Tripodi M, Ferri R. Department of Neurology I.C., Sleep Research Centre, Oasi Institute for Research on Mental Retardation and Brain Aging (IRCCS), Via Conte Ruggiero 73, 94018 Troina, Italy.

Part III: Implication of Dopaminergic System in REM Sleep Behavior Disorder

Chapter 8: The Role of Reduced Striatal Dopamine Transporters in Idiopathic Rapid Eye Movement Sleep Behavior Disorder

Contributor/s: Dr Ilonka Eisensehr, R. Linke, S. Noachtar, J. Schwarz, F. J. Gildehaus and K. Tatsch Department of Neurology, University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany E-mail:

Chapter 9: Rapid Eye Movement Sleep Behavior Disorder in Multiple System Atrophy: The Role of Decreased Nigrostriatal Dopaminergic Projections in the Pathophysiology.

Contributor/s: S. Gilman, MD, F. Consens MD, Department of Neurology, University of Michigan, Ann Arbor, USA.

Chapter 10: The Use of Domapine Agonists in REM Sleep Behavior Disorder: What Does the Data Show?

Contributor; Schmidt MH, Koshal VB, Schmidt HS. Ohio Sleep Medicine and Neuroscience Institute, Dublin, OH 43017, USA.

Part IV: Dopamine and Sleep-Related Movement Disorders. What does imaging Tell Us?

Chapter 11: The Use of Functional Brain Imaging in Investigating the Role of Dopamine in Combined Motor and Sleep Disorders-

Contributor/s: Hilker R, Burghaus L, Razai N, Jacobs AH, Szelies B, Heiss WD. Department of Neurology, Medical University of Cologne, Germany.

Chapter 12: SPECT imaging of striatal pre- and postsynaptic dopaminergic status in restless legs syndrome with periodic leg movements in sleep.

Contributor/s: Michaud M, Soucy JP, Chabli A, Lavigne G, Montplaisir J. Departement de Psychiatrie Faculte de Medecine Universite de Montreal, Canada.

Chapter 13: Combination of ‘Idiopathic’ REM Sleep Behavior Disorder and Olfactory Dysfunction as Possible Indicator for a-Synucleinopathy Demonstrated by Dopamine Transporter FP-CIT-SPECT.

Contributor/s: Stiasny-Kolster K, Doerr Y, Moller JC, Hoffken H, Behr TM, Oertel WH, Mayer G. Department of Neurology, Center of Nervous Diseases, Philipps University of Marburg, Germany.

Chapter 14: Striatal D2 Receptor Binding in Sleep Bruxism: Data from Single-Photon-Emission Computed Tomography.

Contributor/s: Lobbezoo F. Faculte de Medecine Dentaire, Universite de Montreal, Quebec, Canada.

Part V: Dopamine in the Treatment of Sleep-Related Movement Disorders: The Downside.

Chapter 15: Sleep Attacks in Parkinson’s Patients Taking Dopamine Agonists: Is it the Disease or the Drug?

Contributor/s: Comella CL. Department of Neurological Sciences, Rush Medical Center, Chicago, IL 60612, USA.

Chapter 16: The Pathophysiology of Dopaminergic-Therapy-Related Augmentation in Restless Legs Syndrome: Less is More.

Contributor/s: Paulus W, Trenkwalder C. Department of Clinical Neurophysiology, University of Gottingen, Gottingen, Germany.

Chapter 17: Pathologic Gambling in Patients with Restless Legs Syndrome Treated with Dopaminergic Agonists.

Contributor/s: Tippmann-Peikert M, Mayo Clinic Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)