The Kidney: Physiology and Pathophysiology

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Since the publication of the previous edition, our understanding of the molecular and structural basis of electrolyte and water metabolism has expanded enormously. This new edition of The Kidney illuminates these basic science principles clearly and thoroughly while also providing comprehensive and clear clinical management.

This edition has been thoroughly revised and updated. Tight editing and rigorous revision of the chapters, along with elimination of redundancy, have ...

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Overview

Since the publication of the previous edition, our understanding of the molecular and structural basis of electrolyte and water metabolism has expanded enormously. This new edition of The Kidney illuminates these basic science principles clearly and thoroughly while also providing comprehensive and clear clinical management.

This edition has been thoroughly revised and updated. Tight editing and rigorous revision of the chapters, along with elimination of redundancy, have enabled us to return to a two-volume work. At more than 3,100 pages, with over 1,200 illustrations and hundreds of tables, The Kidney remains "highly recommended for anyone active in renal research or clinical nephrology." (The Clinical Investigator; Vol. 20, no. 8, 1992.)

FEATURES:

  • Great for those looking for something substantial on the science behind kidney disease.
  • Takes a pathophysiologic/basic science approach, but includes clinical correlations.
  • New information on the molecular biology of disease processes.

The book contains black-and-white illustrations.

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Editorial Reviews

Jens Goebel
This is the third edition of a comprehensive text on renal physiology and pathophysiology. It has been compacted into two volumes largely by avoiding redundance and omitting topics only marginally related to kidney disease, yet it contains 57 new chapters (out of 104 total) compared to the second edition published in 1992. The book convincingly meets its stated purpose of providing ""an explanatory framework for the understanding of the mechanisms underlying internal exchanges of water and electrolytes and the key regulatory role of the kidney in responding to normal and abnormal disturbances."" It appears to be written for both basic scientists and clinicians in the field of nephrology and for trainees in either pathway. In its entirety, it may be somewhat overwhelming for medical students or residents, although it certainly provides ample material for selective reading on individual topics. The material is presented by over 100 different authors, all experts in their fields as researchers or clinicians, and organized well by the two editors. This is an excellent in-depth compilation of all aspects of renal physiology in health and disease, presented in well-balanced in chapters with high-quality figures and ample references. As an extra treat, the chapters are preceded by a rich summary of renal physiology to 1950 written by the late Carl Gottschalk. This book clearly represents an excellent, useful, usable, and (in view of recent rapid scientific progress) needed update of the previous edition and will have a prominent place on my bookshelf as well as those of many others in the field.
Booknews
A revised and expanded (to three volumes) edition of the reference- text first published in 1985. In preparing the second edition, the editors took cognizance of the dual requirements to provide a comprehensive treatment of normal and deranged water and electrolyte metabolism that is physiologically oriented and at the same time incorporates the new domain of the molecular biology of the kidney. The general organization of a the book remains the same, with the focus on renal physiology rather than on the broad field of nephrology. The number of chapters has been increased from 92 to 110. Several large chapters from the first edition have been divided into two separate ones to facilitate more detailed coverage. A new section on the molecular biology of transport, comprised of seven chapters, has been added. Some 70 new senior authors assume responsibility for about three dozen new chapters and the revision of an equal number of chapters previously included. More than half of the book is written by new individuals. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Doody's Review Service
Reviewer: Jens Goebel, MD (Cincinnati Children's Hospital Medical Center)
Description: This is the third edition of a comprehensive text on renal physiology and pathophysiology. It has been compacted into two volumes largely by avoiding redundance and omitting topics only marginally related to kidney disease, yet it contains 57 new chapters (out of 104 total) compared to the second edition published in 1992.
Purpose: The book convincingly meets its stated purpose of providing "an explanatory framework for the understanding of the mechanisms underlying internal exchanges of water and electrolytes and the key regulatory role of the kidney in responding to normal and abnormal disturbances."
Audience: It appears to be written for both basic scientists and clinicians in the field of nephrology and for trainees in either pathway. In its entirety, it may be somewhat overwhelming for medical students or residents, although it certainly provides ample material for selective reading on individual topics. The material is presented by over 100 different authors, all experts in their fields as researchers or clinicians, and organized well by the two editors.
Features: This is an excellent in-depth compilation of all aspects of renal physiology in health and disease, presented in well-balanced in chapters with high-quality figures and ample references. As an extra treat, the chapters are preceded by a rich summary of renal physiology to 1950 written by the late Carl Gottschalk.
Assessment: This book clearly represents an excellent, useful, usable, and (in view of recent rapid scientific progress) needed update of the previous edition and will have a prominent place on my bookshelf as well as those of many others in the field.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780881677737
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 11/28/1991
  • Edition description: REV
  • Edition number: 2
  • Pages: 3816

Table of Contents

Preface to the First Edition
Preface to the Second Edition
Preface
Acknowledgments
Introduction; A History of Renal Physiology to 1950 by Carl W. Gottschalk
Addendum
In Memoriam

Section I:
General Principles of Epithelial and Nonepithelial Transport
Mechanisms of Water and Electrolyte Transport
Epithelial Organization

Section II:
Organization of the Kidney
Structural Organization
Renal Differentiation and Growth
Functional Organization

Section III:
The Kidney as an Endocrine Organ

Section IV:
Water and Electrolyte Exchanges
Renal Regulation of Water Balance
Renal Regulation of Sodium and Chloride
Renal Regulation of Potassium
Renal Regulation of Magnesium
Renal Regulation of Calcium
Renal Regulation of Phosphorous
Renal Regulation of Acid-Base Balance
Renal Regulation of Organic Solutes
Renal Regulation of Proteins and Macromolecules

Section V:
Extrinsic and Intrinsic Renal Failure
Impairment of Renal Function
Renal Pharmacology

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