The Mesothelial Cell and Mesothelioma

Overview

Detailing the epidemiology, immunocytochemistry, and molecular and cellular biology of mesothelioma, this up-to-date reference describes mesothelial cell transformation under the effect of mineral fibers - providing a thorough evaluation of the various therapeutic approaches to mesothelioma. Considering mesothelioma in the context of the overall biological effects of asbestos, The Mesothelial Cell and Mesothelioma offers much-needed information to help prevent, diagnose, and manage mesothelial carcinogenesis ... ...
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Overview

Detailing the epidemiology, immunocytochemistry, and molecular and cellular biology of mesothelioma, this up-to-date reference describes mesothelial cell transformation under the effect of mineral fibers - providing a thorough evaluation of the various therapeutic approaches to mesothelioma. Considering mesothelioma in the context of the overall biological effects of asbestos, The Mesothelial Cell and Mesothelioma offers much-needed information to help prevent, diagnose, and manage mesothelial carcinogenesis ... explores the possibility of a hereditary predisposition for malignant mesothelioma ... examines the phenotypical and genotypical changes associated with mesothelial cell transformation ... explains the use of transmission electron microscopy as well as specific and unspecific antibodies in diagnosing mesothelioma ... discusses whether there is or has been a background incidence of mesothelioma in humans unrelated to the industrial use of asbestos ... analyzes new treatment strategies, including gene therapy, immunotherapy, and chemotherapy ... and more.

This book contains black-and-white illustrations.

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Editorial Reviews

Booknews
In the context of the overall biological effects of asbestos, details the epidemiology, immunocytochemistry, and molecular and cellular biology of the transformation of mesothelial cell in response to mineral fibers, as an aid to preventing, diagnosing, and managing mesothelial carcinogenesis or mesothelioma. Among the topics are the historical background to mesothelioma, the possibility of genetic disposition, the pathogenesis of serosal lesions after asbestos exposure, establishing and characterizing cell lines, and several diagnostic and therapeutic techniques. The subject index is quite brief. Annotation c. Book News, Inc., Portland, OR booknews.com
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Product Details

  • ISBN-13: 9780824792329
  • Publisher: Taylor & Francis
  • Publication date: 7/1/1994
  • Series: Lung Biology in Health and Disease Series , #78
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 368
  • Product dimensions: 9.00 (w) x 6.00 (h) x 0.94 (d)

Table of Contents

Historical Background and Perspectives of Mesothelioma, J. Christopher Wagner Environmental Mesothelioma, Nicholas de Klerk Mesothelioma: Is There a Background?, J. Corbett McDonald and Alison D. McDonald Is There a Genetic Predisposition to Malignant Mesothelioma?, Henry T. Lynch, Hoda Anton-Culver, and Tom Kurosaki Clinical Diagnosis of Pleural Malignancies, Christian Boutin, J.-R. Viallat, Françoise Rey, and Philippe Astoul The Pathogenesis of Malignant and Nonmalignant Serosal Lesions in Body Cavities Consequent to Asbestos Exposure, John E. Craighead and Agnes B. Kane Immunohistochemical Diagnosis of Mesothelioma, Jacques F. Legier and John C. Maddox Cytological Diagnosis of Malignant Mesothelioma, Theodorus H. van der Kwast, M. Delahaye, and Jocelyn Fleury Establishment and Characterization of Human Normal and Malignant Mesothelial Cell Lines, Marjan A. Versnel, Theodorus H. van der Kwast, Henk C. Hoogsteden, and Anne Hagemeijer Experimental and Spontaneous Mesotheliomas, John M. G. Davis Neoplastic Transformation of Mesothelial Cells, Marie-Claude Jaurand and J. Carl Barrett Mesothelial Carcinogenesis: Possible Avenues of Growth Factor Promotion, Brenda I. Gerwin Chromosomal Abnormalities in Human Malignant Mesothelioma, Sakari Knuutila, L. Tammilehto, and K. Mattson Immunobiology and Immunotherapy of Malignant Mesothelioma, Bruce W. S. Robinson Chemotherapy of Malignant Mesothelioma, Pierre Ruffié
Therapeutic Studies of Malignant Mesothelioma in Nude Mice, A. Philippe Chahinian New Therapeutic Approaches in Mesothelioma, Jean Bignon, Isabelle Monnet, Pierre Ruffié, Marie-Claude Jaurand, and Heddi Haddada

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