The Neurobiology of Disease: Contributions from Neuroscience to Clinical Neurology

The Neurobiology of Disease: Contributions from Neuroscience to Clinical Neurology

by Hugh Bostock
     
 

ISBN-10: 0521342384

ISBN-13: 9780521342384

Pub. Date: 06/30/2011

Publisher: Cambridge University Press

Demonstrating the value of interactions between neurology and the basic sciences that underpin it, this volume considers a range of topics from the points of view of both neurobiologist and clinician and reveals how advances in our understanding have been and continue to be made. The selected topics cover a wide range of levels of organization in the nervous system.…  See more details below

Overview

Demonstrating the value of interactions between neurology and the basic sciences that underpin it, this volume considers a range of topics from the points of view of both neurobiologist and clinician and reveals how advances in our understanding have been and continue to be made. The selected topics cover a wide range of levels of organization in the nervous system. For each one, distinguished researchers from around the world have made contributions, including general reviews of normal and pathological mechanisms as well as detailed accounts of the basic processes involved.

Product Details

ISBN-13:
9780521342384
Publisher:
Cambridge University Press
Publication date:
06/30/2011
Pages:
464
Product dimensions:
6.00(w) x 9.00(h) x 1.20(d)

Table of Contents

List of contributors
Preface
1Ion channels in normal and pathophysiological mammalian peripheral myelinated nerve3
2Molecular anatomy of the node of Ranvier: newer concepts13
3Delayed rectifier type potassium currents in rabbit and rat axons and rabbit Schwann cells29
4Axonal signals for potassium channel expression in Schwann cells37
5Ion channels in human axons47
6An in vitro model of diabetic neuropathy: electrophysiological studies61
7Autoimmunity at the neuromuscular junction69
8Immunopathology and pathophysiology of experimental autoimmune encephalomyelitis75
9Pathophysiology of human demyelinating neuropathies86
10Conduction properties of central demyelinated axons: the generation of symptoms in demyelinating disease95
11Mechanisms of relapse and remission in multiple sclerosis118
12Glial transplantation in the treatment of myelin loss or deficiency124
13Human nociceptors in health and disease151
14Sensory consequences of inflammation162
15Non-voluntary muscle activity and myofascial pain syndromes169
16Is there a mechanism for the spinal cord to remember pain?177
17The neurophysiological basis of pain relief by acupuncture189
18Synaptic transduction in neocortical neurones201
19Cortical circuits, synchronization and seizures210
20Physiologically induced changes of brain temperature and their effect on extracellular field potentials221
21Fusimotor control of the respiratory muscles231
22Cerebral accompaniments and functional significance of the long-latency stretch reflexes in human forearm muscles241
23The cerebellum and proprioceptive control of movement247
24Roles of the lateral nodulus and uvula of the cerebellum in cardiovascular control257
25Central actions of curare and gallamine: implications for reticular reflex myoclonus?266
26Pathophysiology of upper motoneurone disorders276
27Modulation of hypoglossal motoneurones by thyrotropin-releasing hormone and serotonin283
28Serotonin and central respiratory disorders in the newborn292
29Are medullary respiratory neurones multipurpose neurones?299
30Reflex control of expiratory motor output in dogs309
31Abnormal thoraco-abdominal movements in patients with chronic lung disease318
32Respiratory rhythms and apnoeas in the newborn327
33Cardiorespiratory interactions during apnoea337
34Impairment of respiratory control in neurological disease348
35The respiratory muscles in neurological disease358
36Axonal growth and plasticity in the adult nervous system373
37Target dependence of motoneurones379
38Rescue of neurones cross-regenerated into foreign targets395
39Development and repair of neonatal mammalian spinal cord in culture405
40Selective neuronal vulnerability in motor neurone diseases with reference to sparing of Onuf's nucleus411
41Excitotoxicity in motor neurone diseases427
Index436

Read More

Customer Reviews

Average Review:

Write a Review

and post it to your social network

     

Most Helpful Customer Reviews

See all customer reviews >