The Neutrophil

Paperback (Softcover reprint of the original 1st ed. 1976)
$99.00 price
Other sellers (Paperback)
  • All (6) from $91.77   
  • New (5) from $91.77   
  • Used (1) from $154.27   
Sending request ...

More About This Book

Product Details

  • ISBN-13: 9781468474206
  • Publisher: Springer US
  • Publication date: 12/31/2013
  • Edition description: Softcover reprint of the original 1st ed. 1976
  • Pages: 217
  • Product dimensions: 5.98 (w) x 9.02 (h) x 0.49 (d)

Table of Contents

1 Blood Cells.- 1.1. Platelets.- 1.2. White Cells.- 1.2.1. Lymphocytes.- 1.2.2. Monocytes.- 1.2.3. Polymorphonuclear Cells.- Selected Reading.- 2 Morphology and Cellular Physiology of Neutrophil Granulocytes.- 2.1. The Nucleus.- 2.2. Nucleic Acid Metabolism.- 2.3. The Cytoplasm.- 2.3.1. Carbohydrate Metabolism.- 2.3.2. Protein Synthesis.- 2.4. The Granules.- 2.5. Cell Movement.- 2.6. Directed Cell Movement.- 2.7. Microtubules and Degranulation.- 2.8. The Cell Membrane.- Selected Reading.- 3 The Origin and Development of Neutrophils.- 3.1. The Bone Marrow and Neutrophil Precursors.- 3.1.1. Granule Formation.- 3.1.2. Functional Differences Between Neutrophils and Their Precursors.- 3.2. Rates of Cell Division in Neutrophil Precursors.- 3.2.1. Morphological Methods.- 3.2.2. Tritiated Thymidine Methods.- 3.2.3. Critique of Marrow Kinetic Methods.- 3.2.4. Ineffective Granulopoiesis?.- 3.2.5. DFP Methods.- 3.3. Neutrophil Precursors Which Cannot Be Recognized Morphologically.- 3.3.1. The Hemopoietic Stem Cell.- 3.3.2. The Colony-Forming Cell.- 3.4. Summary.- Selected Reading.- 4 Tissue Consumption of Granulocytes and Control Mechanisms for Granulopoiesis.- 4.1. Distribution, Function, and Disposal of Neutrophils.- 4.2. Control of the Blood Neutrophil Level.- 4.2.1. Mobilization from Capillary Walls.- 4.2.2. Mobilization of the Mature Pool from Bone Marrow.- 4.2.3. Chalones.- 4.2.4. The Colony-Stimulating Factor.- 4.2.5. Stem Cell Controls.- 4.3. Summary.- 5 Inflammation and Chemotaxis.- 5.1. Inflammation.- 5.1.1. Gross Aspects.- 5.1.2. Microscopic Aspects.- 5.1.3. Increased Vascular Permeability.- 5.1.4. Emigration of Cells from Vessels.- 5.1.5. Mediators of Inflammation.- 5.2. Chemotaxis.- 5.2.1. Chemotaxis on Glass Slides.- 5.2.2. The Boyden Chamber.- 5.2.3. The System of Zigmond and Hirsch.- 5.2.4. Chemotactic Substances.- 5.2.5. The Serine Esterase of Neutrophil Membranes.- 5.2.6. Neutrophil-Immobilizing Factors.- 5.3. Antagonists of Inflammation.- 5.4. Summary.- Selected Reading.- 6 Phagocytosis.- 6.1. Mechanisms of Phagocytosis.- 6.1.1. General Considerations.- 6.1.2. Surface Phagocytosis.- 6.1.3. The Heat-Labile Opsonin System.- 6.1.4. Opsonization Mediated by Antibodies.- 6.1.5. Receptors on Neutrophil Membranes.- 6.2. Physiological Significance of Phagocytic Mechanisms.- 6.3. Summary.- 7 Degranulation and Intracellular Killing of Bacteria.- 7.1. Historical Aspects.- 7.2. Phagocytin.- 7.3. Degranulation.- 7.3.1. Specific Degranulation.- 7.3.2. Possible Membrane-Fusion Mechanisms.- 7.4. Intracellular Killing of Bacteria.- 7.4.1. Oxygen and Bacterial Killing.- 7.4.2. Myeloperoxidase.- 7.4.3. Oxidative Killing of Bacteria.- 7.4.4. Oxidative Killing Mechanisms Not Involving Peroxidase.- 7.4.5. Nonoxidative Bactericidal Mechanisms.- 7.5. Summary.- 8 Other Activities of Neutrophils.- 8.1. Extracellular Release of Neutrophil Granule Contents.- 8.1.1. Enzyme Release During Phagocytosis.- 8.1.2. Enzyme Release During “Frustrated Phagocytosis”.- 8.1.3. Enzyme Release Stimulated by Chemotactic Factors.- 8.1.4. Enzyme Release After Cell Death.- 8.1.5. Cell Lysis from Within.- 8.2. Enzymes Responsible for Tissue Damage.- 8.2.1. Cathepsins.- 8.2.2. Neutral Proteases.- 8.3. Abscess Formation.- 8.4. The Arthus Reaction.- 8.5. Nephrotoxic Nephritis.- 8.6. Serum Sickness.- 8.7. The Schwartzman Reaction.- 8.8. Human Diseases Involving Neutrophils.- 8.9. Neutrophils and Tissue Repair.- 8.10. Fever and Other Hormonally Mediated Responses to Infection.- References.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)