The Pediatric Cardiac Anesthesia Handbook / Edition 1

The Pediatric Cardiac Anesthesia Handbook / Edition 1

ISBN-10:
1119095530
ISBN-13:
9781119095538
Pub. Date:
04/24/2017
Publisher:
Wiley
ISBN-10:
1119095530
ISBN-13:
9781119095538
Pub. Date:
04/24/2017
Publisher:
Wiley
The Pediatric Cardiac Anesthesia Handbook / Edition 1

The Pediatric Cardiac Anesthesia Handbook / Edition 1

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Overview

Written by an expert author team at the renowned Boston Children's Hospital, USA, The Pediatric Cardiac Anesthesia Handbook provides a comprehensive yet concise overview of the anesthetic management of pediatric patients with congenital heart disease.

This book is divided into two parts. The first part provides an introduction to the basic assessment of patients, including cardiovascular physiology, pathophysiology and the underlying concepts in coronary heart disease, preoperative evaluation, intraoperative management, and interpretation of cardiac catheterization data. The second part of the book addresses disorders and diseases in a templated manner covering the anatomical and physiological features, surgical therapies, anesthetic approach and postoperative management. Chapters on the heart and heart and lung transplantation consider the additional complexities of those patients and anesthetic considerations for non-cardiac surgery after heart transplantation.

The anesthesiologist caring for patients with congenital heart disease faces a myriad of challenges in the perioperative management of these complex individuals. This book provides:

  • A concise and easily referable guide ideal for use during anesthesiology residency training and fellowships.
  • A templated chapter layout ideal for easy referral by wider members of the multidisciplinary team, such as cardiologists, cardiac intensivists, perfusionists, and surgeons.
  • Helpful illustrations and a bulleted content for rapid reference.
  • Guidelines on specific lesions for the pediatric anesthesiologist caring for cardiac patients presenting for non-cardiac surgery.

This book is a valuable resource for all anesthesiology and cardiac critical care providers who manage patients with congenital heart disease, and an ideal study aid.


Product Details

ISBN-13: 9781119095538
Publisher: Wiley
Publication date: 04/24/2017
Pages: 288
Sales rank: 737,949
Product dimensions: 7.00(w) x 9.90(h) x 0.60(d)

About the Author

Viviane G. Nasr, MD graduated from Medical School at the American University of Beirut (AUB), Lebanon in 2003, and pursued a residency in anesthesiology at AUB and Tufts Medical Center, Boston. She completed a pediatric anesthesia fellowship at Children's National Medical Center (CNMC) in Washington DC and a pediatric cardiac anesthesia fellowship at Boston Children's Hospital. She is American Board certified in Anesthesiology and Pediatric Anesthesiology and an active member of the Congenital Cardiac Anesthesia Society.

James A. DiNardo, MD graduated from Dartmouth College and Dartmouth Medical School (with honors). He completed his anesthesia residency and fellowship in Cardiac Anesthesia at Beth Israel Hospital in Boston. He joined faculty at Boston Children's Hospital in 1999 where he currently serves as the Chief of the Division of Cardiac Anesthesia. He spends approximately one third of this clinical time as an Attending in the Cardiac ICU.
Dr DiNardo is certified in perioperative TEE and is former Chairman of the PTEeXAM Committee. He is also a Senior Oral Board Examiner for the ABA, a member of the ABA Pediatric Examination Writing Committee, and Chair of the Pediatric MOCA Examination Committee. He is Past-President of both the Congenital Cardiac Anesthesia Society and the Association of Cardiac Anesthesiologists. He is currently the Anesthesia and Analgesia Executive Editor for Pediatric Anesthesia.
He is the author of a major textbook on cardiac anesthesia and of more than 160 peer-reviewed articles and book chapters.

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Table of Contents

Preface xvii

Part I The Basics 1

1 Cardiovascular Development 3

Embryology 3

Cardiovascular Physiology 3

Fetal Circulation 3

Closure of the Ductus Arteriosus 5

Closure of the Foramen Ovale 6

Closure of the Ductus Venosus 6

Pulmonary Vascular Changes 6

Myocardial Performance in the Neonate 7

Hemodynamic Changes at Birth 7

2 Important Concepts in Congenital Heart Disease 9

Pathophysiology of CHD 9

Concepts of Shunting, Single‐Ventricle Physiology, and Inter‐Circulatory Mixing 9

Shunting 9

Effective Blood Flow 10

Total Pulmonary Blood Flow/Total Systemic Blood Flow 10

Single‐Ventricle Physiology 10

Intercirculatory Mixing 13

Classification of Anatomic Shunts 15

Simple Shunts 15

Complex Shunts 15

Pulmonary Vascular Pathophysiology 18

Causes of Pre‐Capillary PH in CHD 18

Causes of Post‐Capillary PH in CHD 18

Control of Pulmonary Vascular Resistance 19

PaO2 19

PaCO2 19

pH 19

Variation in Lung Volumes 19

Vasodilator Agents 20

Sympathetic Nervous System Stimulation 20

Myocardial Ischemia 21

Aortic Diastolic Pressure 21

Subendocardial Pressure 21

Heart Rate 22

Anatomic Coronary Artery Lesions 22

3 Preoperative Evaluation 23

Clinical History 23

Physical Examination 23

Associated Congenital Abnormalities 24

Laboratory Data 25

Pregnancy 26

Psychological Considerations 26

Preoperative Preparation 27

Preoperative Fluid Therapy 27

Preoperative Medications 29

4 Intraoperative Management 31

Intraoperative Monitoring 31

ECG and Blood Pressure 31

Systemic Oxygen Saturation 32

End‐Tidal CO2 32

Central Venous Pressure 32

Temperature 33

Near‐Infra‐Red Spectroscopy 33

Transcranial Doppler 34

Transesophageal Echocardiography (TEE) 35

Airway Management 35

Anesthesia Induction and Maintenance 36

Induction of Anesthesia 36

Mask Induction 36

Intravenous Induction 36

Maintenance of Anesthesia 37

5 Interpretation of Cardiac Catheterization Data 39

Right‐Heart Catheterization 39

Right Atrial Pressure (RAP) Waveform 39

Right Ventricular Pressure (RVP) Waveform 39

Pulmonary Artery Pressure (PAP) Waveform 40

Left‐Heart Catheterization 40

Left Atrial Pressure (LAP) Waveform 41

Left Ventricular Pressure (LVP) Waveform 41

Aortic Pressure Waveform 41

Left Ventriculography 41

Coronary Angiography 43

Coronary Anatomy 43

Anatomic Coronary Lesions 44

Coronary Collaterals 45

Cardiac Output Determination 45

Thermodilution Technique 45

Fick Determination 45

Evaluation of Cardiac Shunts 46

Shunt Location 46

Shunt Quantification 46

Saturation Data 48

Resistances 48

Assessment of Pulmonary Vascular Anatomy 48

Evaluation of the Pulmonary Vasculature 48

Pulmonary Artery Wedge Angiogram 48

Pulmonary Vein Wedge Angiogram 49

Assessment of Pulmonary Arterial Hypertension 49

Assessment of Valve Lesions 50

Stenotic Lesions 50

Regurgitant Lesions 50

6 Cardiopulmonary Bypass 51

The Cardiopulmonary Bypass Circuit 51

Differences Between Adult and Pediatric CPB 53

CPB Flow Rates 53

Anesthesia During CPB 53

Monitoring During CPB 54

Hemodilution 54

Priming Solution 54

Ultrafiltration 55

Conventional Ultrafiltration 55

Modified Ultrafiltration 55

Blood Gas Management 55

Deep Hypothermic Circulatory Arrest and Regional Perfusion Techniques 57

Anticoagulation 57

Protamine Reversal 58

7 Mechanical Support Devices 59

Extracorporeal Membrane Oxygenation (ECMO) 59

Indications 59

Relative Contraindications 59

Modes of ECMO Support 59

Veno‐Venous (VV)‐ECMO 59

Veno‐Arterial (VA)‐ECMO 59

Device and Patient Complications 60

Common Terminology Used During an ECMO Run 61

Intraoperative Considerations for Patients on ECMO 61

Ventricular Assist Devices (VADs) 62

Indications 62

Relative Contraindications 62

Modes of VADs 62

Complications 62

Anesthetic Considerations for Patients Receiving VAD 62

Induction of Anesthesia and Pre‐Bypass Management 64

Post‐VAD Placement Management 65

BiVAD Insertion 65

Part II Specific Lesions 67

8 Patent Ductus Arteriosus 69

Introduction 69

Anatomy 69

Physiology 69

Surgical Therapy 69

Catheterization Laboratory Intervention 70

Anesthetic Management 70

Induction and Maintenance 70

Non‐Cardiac Surgery 71

9 Aortopulmonary Window 73

Introduction 73

Anatomy 73

Physiology 73

Surgical Management 73

Catheterization Laboratory Intervention 74

Anesthetic Management 75

Non‐Cardiac Surgery 75

10 Coarctation of the Aorta 77

Introduction 77

Anatomy 77

Physiology 77

Surgical Therapy 80

Catheterization Laboratory Intervention 80

Anesthetic Management 81

Induction and Maintenance 81

Management after Cross‐Clamp Removal 82

Non‐Cardiac Surgery 82

11 Atrial Septal Defect 83

Introduction 83

Anatomy 83

Ostium Secundum ASD 83

Ostium Primum ASD 83

Sinus Venosus Defects 84

Coronary Sinus Defect 84

Physiology 85

Surgical Therapy 85

Catheterization Laboratory Intervention 85

Anesthetic Management 86

Induction and Maintenance 86

Post‐CPB Management 86

Non‐Cardiac Surgery 87

12 Ventricular Septal Defect 89

Introduction 89

Anatomy 89

Subpulmonary or Supracristal Defects 89

Membranous or Perimembranous Defects 89

Conoventricular Defects 89

Inlet or Canal‐Type Defects 89

Muscular Defects 89

Physiology 89

Surgical Therapy 91

Catheterization Laboratory Intervention 91

Anesthetic Management 91

Induction and Maintenance 91

Post‐CPB Management 91

Non‐Cardiac Surgery 92

13 Atrioventricular Canal Defects 93

Introduction 93

Anatomy 93

Partial AVC 93

Transitional AVC 93

Complete AVC (CAVC) 93

Unbalanced AVC 94

Physiology 94

Surgical Therapy 95

Anesthetic Management 95

Induction and Maintenance 95

Post‐CPB Management 96

Non‐Cardiac Surgery 96

14 Double Outlet Right Ventricle 97

Introduction 97

Anatomy 97

Physiology 99

Surgical Therapy 100

Anesthetic Management 101

Induction and Maintenance 101

Post‐CPB Management 101

15 Truncus Arteriosus 103

Introduction 103

Anatomy 103

Physiology 104

Surgical Therapy 104

Catheterization Laboratory Intervention 105

Anesthetic Management 105

Goals 105

Induction and Maintenance 105

Post‐CPB Management 105

Goals 106

16 Total Anomalous Pulmonary Venous Return 107

Introduction 107

Anatomy 107

Physiology 108

Surgical Therapy 109

Anesthetic Management 109

Goals 109

Induction and Maintenance 110

Post‐CBP Management 110

Goals 110

Long‐Term Outcomes 110

17 Left Ventricular Outflow Tract Obstruction 113

Introduction 113

Anatomy 113

Physiology 113

Surgical Therapy 114

Catheterization Laboratory Intervention 114

Anesthetic Management 114

Goals 114

Induction and Maintenance 115

Post‐CPB Management 115

18 Mitral Valve 117

Mitral Valve Stenosis 117

Introduction 117

Anatomy 117

Physiology 118

Surgical Therapy 118

Catheterization Laboratory Intervention 118

Anesthetic Management 118

Goals 118

Pre‐Induction 119

Induction and Maintenance 119

Post‐Cardiopulmonary Bypass (CPB) Management 120

Mitral Valve Regurgitation 121

Introduction 121

Anatomy 121

Physiology 121

Surgical Management 122

Catheterization Laboratory Intervention 122

Anesthetic Management in Mitral Regurgitation 122

Goals 122

Premedication 122

Induction and Maintenance 122

Post‐CPB Management 123

19 Pulmonary Atresia/Intact Ventricular Septum (PA/IVS) 125

Introduction 125

Anatomy 125

Physiology 125

Surgical and Catheter‐Based Therapy 126

Anesthetic Management 129

Goals 129

Post‐CPB Management 129

20 Tetralogy of Fallot (TOF) 131

Introduction 131

Anatomy 131

Physiology 131

Hypoxic or Hypercyanotic Episodes (‘Tet Spells’) 132

Surgical Therapy 134

Palliative Shunts 134

Definitive Repair 136

Catheterization Laboratory Intervention 136

Anesthetic Management 137

Goals 137

Induction and Maintenance 137

Post‐CPB Management 138

Goals 138

Postoperative Junctional Ectopic Tachycardia 139

Non‐Cardiac Surgery 139

21 Tetralogy of Fallot with Pulmonary Atresia (TOF/PA) 141

Anatomy 141

Physiology 141

Surgical Therapy 141

Anesthetic Management 143

Post‐CPB Management 143

22 Tetralogy of Fallot with Absent Pulmonary Valve (TOF/APV) 145

Anatomy 145

Physiology 145

Surgical Therapy 146

Anesthetic Management 146

Post‐CPB Management 146

23 Transposition of the Great Arteries (TGA) 147

Introduction 147

Anatomy 147

Physiology 148

Surgical Therapy 151

Anatomic Repair or the Arterial (Jatene) Switch Procedure 151

Intra‐Atrial Physiologic Repair: Mustard and Senning Procedures 153

Rastelli, Lecompte, and Nikaidoh Procedures 154

Anesthetic Management 155

Goals 155

Induction and Maintenance 155

Post‐CPB Management 155

Goals 155

Non‐Cardiac Surgery 157

Congenitally Corrected Transposition of the Great Vessels 157

Introduction 157

Anatomy 157

Physiology 158

Surgical Management 158

Traditional Repair for C‐TGV 158

Double Switch Procedure and Atrial Switch‐Rastelli Procedures 158

24 Single‐Ventricle Lesions 161

Introduction 161

Physiology and Initial Procedures 161

Initial Procedures to Optimize Pulmonary Arterial Blood Flow 161

Initial Procedures to Optimize Pulmonary Venous Blood Flow 163

Initial Procedures to Optimize Systemic Blood Flow 163

Management of Single‐Ventricle Physiology 164

Anesthetic Management, Pre‐Initial Repair 166

Goals 166

Induction and Maintenance 167

Post‐CPB Management, Post‐Initial Repair 167

Goals 167

Single‐Ventricle Pathway, Superior Cavopulmonary Shunt or Bidirectional Glenn (BDG) 169

Anesthetic Management, Pre‐Superior Cavopulmonary Shunt 171

Goals 171

Induction and Maintenance 171

Post‐CPB Management, Post‐Superior Cavopulmonary Shunt 171

Goals 171

Definitive Repair: The Fontan Procedure or Total Cavopulmonary Connection (TCPC) 172

Fontan Physiology 172

Fenestrated Fontan 176

Anesthetic Management, Pre‐Fontan 176

Goals 176

Induction and Maintenance 177

Post‐CPB Management, Post‐Fontan Procedure 177

Goals 177

Non‐Cardiac Surgery 180

25 Hypoplastic Left Heart Syndrome 181

Introduction 181

Anatomy 181

Physiology 181

Surgical Therapy 182

Anesthetic Management 183

Goals 183

Post‐CPB Management 183

Biventricular Repair 184

The ‘Borderline’ Left Heart 184

The Left Heart Rehabilitation 184

Staged Left Ventricular Recruitment 184

Biventricular Conversion 185

Non‐Cardiac Surgery 185

26 Interrupted Aortic Arch 187

Introduction 187

Anatomy 187

Physiology 187

Surgical Management 189

Catheterization Laboratory Intervention 189

Anesthetic Management 190

Goals 190

Induction and Maintenance 190

Post‐CPB Management 190

Goals 190

27 Vascular Rings 191

Introduction 191

Anatomy 191

Physiology 191

Surgical Management 191

Catheterization Laboratory Intervention 192

Anesthetic Management 192

28 Tricuspid Atresia 195

Introduction 195

Anatomy 195

Physiology 195

Surgical Therapy 197

Anesthetic Management 197

Goals 197

29 Heart Transplantation 199

The Donor 199

Anesthetic Management of the Recipient 202

Preoperative Evaluation 202

Physical Examination 202

Premedication 202

Preinduction 202

Induction and Maintenance 203

Operative Procedure 205

Post‐CPB Management 207

Goals 207

Preparation for Termination of CPB 207

Impaired Systolic Function 207

Right Ventricular Afterload Mismatch 208

Sinus and Atrioventricular Node Dysfunction 208

Impaired Diastolic Function 208

Termination of CPB 209

Non‐Cardiac Surgery in the Post‐Cardiac Transplant Patient 210

Physiology of the Transplanted Heart 210

Autonomic Nervous System 210

Heart Rate 210

Left Ventricular Systolic Function 211

Right Ventricular Systolic Function 211

Atrial Function 211

Diastolic Function 211

Issues Unique to Heart Transplant Patients 211

Cardiac Allograft Vasculopathy (CAV) 212

Hypertension 212

Atrial and Ventricular Arrhythmias 212

Subacute Bacterial Endocarditis (SBE) Prophylaxis 213

Rejection 213

Response to Drugs 213

Anesthetic Considerations for Non‐Cardiac Surgery in Patients Post Heart Transplantation 215

30 Heart–Lung and Lung Transplantation 217

Introduction 217

Single‐Lung Transplantation 217

Double‐Lung Transplantation 217

Living Donor Lobar Lung Transplant (LDLLT) 218

The Donor 218

Operative Procedure and Patient Positioning 219

Use of CPB 220

HLT and En‐Bloc DLT 220

SLT and BSSLT 220

Anesthetic Management 221

Goals 221

Preoperative Evaluation 221

Premedication 221

Preinduction 221

Management of One Lung Ventilation (OLV) 222

Endobronchial Intubation 222

Single‐Lumen Endotracheal Tube Plus a Bronchial Blocker 222

Single‐Lumen Endotracheal Tube Plus an E‐Z Bronchial Blocker 222

Univent Tube 222

Double‐Lumen Endotracheal Tube 224

Induction and Maintenance 224

Special Considerations for SLT and BSSLT 225

One‐Lung Ventilation 225

Clamping of the PA 226

Allograft Implantation 226

Indications for CPB 226

Post‐CPB Management 227

Postoperative Care 227

Non‐Cardiac Surgery in Lung Transplant Patients 227

Anesthetic Considerations for Non‐Cardiac Surgery in Patients Post Lung Transplantation 229

31 Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery (ALCAPA) 231

Introduction 231

Anatomy 231

Physiology 231

Surgical Treatment 231

Anesthetic Management 232

32 Heterotaxy 233

Introduction 233

Anatomy 233

Position of the Heart in the Chest 233

Atrial Anatomy 233

Venoatrial Connections 233

Ventricular Anatomy 234

Atrioventricular Junction 236

Ventriculoarterial Connections 236

Surgical Therapy 238

33 Ebstein Anomaly 239

Introduction 239

Anatomy 239

Physiology 239

Surgical Treatment 240

Anesthetic Management in Ebstein Anomaly 241

Goals 241

Post‐CPB Management 242

Index 243

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