Perricone Weight-Loss Diet: A Simple 3-Part Program to Lose the Fat, the Wrinkles, and the Years

Perricone Weight-Loss Diet: A Simple 3-Part Program to Lose the Fat, the Wrinkles, and the Years

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by Nicholas Perricone

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From #1 New York Times bestselling author Nicholas Perricone -- respected physician, award-winning research scientist, and trusted expert on health and beauty -- comes the biggest breakthrough in weight loss since Atkins.

Millions of women and men have restored youthful radiance, smoothness, and suppleness to their skin through Dr. Nicholas Perricone’s

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From #1 New York Times bestselling author Nicholas Perricone -- respected physician, award-winning research scientist, and trusted expert on health and beauty -- comes the biggest breakthrough in weight loss since Atkins.

Millions of women and men have restored youthful radiance, smoothness, and suppleness to their skin through Dr. Nicholas Perricone’s advice, care, and transformative eating plan -- and all with the welcome yet unexpected benefit of losing excess weight along with the wrinkles! Building on this discovery, Dr. Perricone breaks new ground with his trademark anti-inflammatory program based on the foods, supplements, and lifestyle changes with the proven ability to accelerate fat loss by increasing metabolism and building and maintaining muscle mass.

Consider this staggering fact: As we age, we can expect to gain ten pounds of fat and lose five pounds of muscle each decade. In three easy steps, Dr. Perricone shows how to fight this weight gain and rebuild muscle mass, and avoid the haggard, aging, and drawn appearance that results from other weight-loss programs.

Inside The Perricone Weight-Loss Diet discover:

  • the rejuvenating and slimming secrets of the anti-inflammatory diet
  • which foods, supplements, and lifestyle changes enable us to lose fat while maintaining muscle
  • how to control hormones such as insulin and cortisol to lose weight
  • how to maintain youthful, firm, and radiantly toned skin on the face and body during weight loss

    As an added bonus, as you follow Dr. Perricone’s program you’ll sleep better, have more energy and less stress, and experience greater mental clarity without the food cravings. Lose the weight, the wrinkles, and the years!

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  • Editorial Reviews

    Library Journal
    The Perricone prescription for toning down the wrinkles can also help tone down the fat and keep up the muscle as we age. With a national tour. Copyright 2005 Reed Business Information.
    From the Publisher
    Advance praise for The Perricone Weight-Loss Diet

    “This significant book shows that Dr. Perricone’s anti-inflammatory program is a powerful tool we have to fight excess weight gain. The anti-inflammatory foods and supplements introduced in this book enable us to fight metabolic syndrome, whose complications lead to obesity and diabetes. Utilizing a wide range of groundbreaking scientific discoveries, Dr. Perricone demonstrates once again that he is at the forefront in finding solutions to difficult problems. Highly recommended!”
    –Harry G. Preuss M.D., M.A.C.N., C.N.S., professor of physiology, medicine, and pathology, Georgetown University Medical Center, and author of Maitake Magic

    “The Perricone Weight-Loss Diet delivers a solid program that will melt away the pounds–while maintaining toned skin and healthy muscle mass. Dr. Perricone proves once again that chronic, subclinical inflammation is not only responsible for accelerated aging, wrinkles, and a host of degenerative diseases, it is at the basis of our current obesity epidemic. If you need to lose weight, this is the book!
    –Oz Garcia, M.S., Ph.D., author of Look and Feel Fabulous Forever: The World’s Best Supplements, Anti-Aging Techniques, and High-Tech Health Secrets

    “Unless we are morbidly obese, we don’t often think of excess weight as anything more than a cosmetic problem. However, in this extraordinary new book, Dr. Perricone proves otherwise. The Perricone Weight-Loss Diet unlocks the secret link between inflammation and unwanted weight gain. By implementing simple, effective strategies, both men and women can shed significant weight–without hunger or deprivation. A brilliant program that keeps its promise.”
    –Vincent C. Giampapa, M.D., F.A.C.S., co-founder, American Academy for Anti-Aging Medicine, and author of Breaking the Aging Code : Maximizing Your DNA Function for Optimal Health and Longevity

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    Product Details

    Random House Publishing Group
    Publication date:
    Product dimensions:
    7.60(w) x 9.30(h) x 1.10(d)

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    The Perricone Weight-Loss Diet

    By Nicholas Perricone, M.D.

    Random House

    Nicholas Perricone, M.D.
    All right reserved.

    ISBN: 0739325663

    Chapter One

    Chapter 1

    Getting Started

    The best way to predict the future is to invent it.
    --Alan Kay, computer genius/visionary

    In writing this book, I have discovered that the greatest gift I can give my readers is permission to eat healthy and delicious food. This might seem strange considering this book is about weight loss, because traditional concepts of weight loss are all about not eating--nevertheless, it is a fact.

    Statistics regarding obesity and excess weight are alarming. The International Obesity Task Force, which is advising the European Union, had estimated in 2003 that about 200 million of the 350 million adults living in what is now the European Union may be overweight or obese. The U.S. Census Bureau's Census 2000 stated that nearly two-thirds of adults in the United States were overweight, and 30.5 percent were obese.

    However, a closer evaluation of the figures in the latest analysis indicated that may be an underestimate.

    We Americans (children and adults) are more confused than ever about what constitutes a healthy diet. According to statistics from the National Institutes of Health, the prevalence of obesity in the United States has almost doubled since 1980.

    And for good reason. For the past several decades, we have been bombarded with all kinds of misinformation about what we should and should not eat or drink. As soon as one scientific study hits the newswires, another one with equally convincing yet contradictory data springs up. From books to videos we are assailed with confusing and opposing points of view from all kinds of experts and pseudo experts. Consequently, figuring out what to eat and what to avoid has become increasingly difficult.

    The Perricone Weight-Loss Diet cuts through the confusion and provides a simple, foolproof eating plan that will improve your health, help to fight the signs of aging, help you to lose weight, and prevent new weight gain. It all begins with learning which foods make this possible and which foods defeat our purpose.


    Back in the 1960s, the then-young baby boomers began a dietary "back to the land" revolution in protest of the post-World War II introduction of processed foods. In typical backlash fashion, everything this generation embraced had to be "whole," "natural," "fresh," "unprocessed," and grown without pesticides and chemical fertilizers. This was the beginning of the health food movement, which is stronger and more powerful than ever, and finally after more than four decades, is becoming increasingly mainstream.

    That was the good news. The bad news is that this was the last positive dietary trend we have seen. Ever since then, we have had one dangerous and poorly-thoughtout plan after another. In addition, fast food has now become a ubiquitous part of our landscape. According to Eric Schlosser, author of Fast Food Nation, on any given day one out of four Americans has a meal from a fast-food restaurant.

    The 1970s saw the introduction of the Atkins low-carbohydrate, high-protein diet. At first glance, the concept made sense; however, there were a number of serious and dangerous flaws (some since amended), among them an overabundance of saturated fats. The '90s reintroduced this craze, slightly modified.

    Perhaps the worst dietary craze belongs to the 1980s, which heralded the age of the no-fat diet. Supermarket shelves were flooded with high-glycemic carbohydrate foods, offering little in the way of nutrients, but plenty in the way of empty calories. These foods became dietary mainstays for many people, especially women, who found themselves indulging in snack foods such as reduced-fat "baked" potato and corn chips, and fat-free rice and corn cakes, cookies, pretzels, and crackers. Suddenly millions of Americans were placing themselves in a chronic inflammatory condition. Why? Because eating these foods provokes a pro-inflammatory rapid rise in blood sugar, resulting in elevated insulin levels.

    Insulin is an important hormone that helps the body utilize blood sugar for energy or store it as glycogen or fat. But if the insulin is released too quickly, it has a pro-inflammatory effect (explored further in Chapter 2). After a rapid rise, there will be a precipitous drop in blood sugar, resulting in feelings of hunger, which can lead to a vicious cycle of overeating. This is why a diet centered on breads, baked goods, snack foods, sweets, and other sugary, starchy foods results in unwanted weight gain and great difficulty in losing weight. Ironically, in this instance, it is not the caloric value of the foods causing the weight gain. In fact, a rice cake only has around 40 calories. However, because it is rapidly converted to sugar in the bloodstream, resulting in the insulin release, it will cause you to store body fat. An insulin release can result in the storage of body fat.

    Our goal in the Perricone Weight-Loss Diet is to learn how to recognize and avoid sugary and starchy foods, so that we maintain even levels of blood sugar and insulin. Recognize? Yes, because many foods that look healthful can contain added sugars, dangerous trans fats (more about these later), and an ingredient called high fructose corn syrup, which will defeat weight-loss goals and have a negative impact on overall health. By following the Perricone Weight-Loss Diet, you will be able to control your appetite, prevent overeating, stop cravings, and burn excess fat for energy.


    Some scientists and researchers believe that many of the health problems of today are caused by our departure from the hunter-gatherer diet, which consisted of nuts, seeds, berries, wild greens, roots, fruits, fish, fowl, and game. This is a fascinating theory and I do agree with the premise that natural, unprocessed foods are always the best choices. To be healthy and maintain normal weight we need all of the food groups--but not those that come from the laboratory. Our protein source needs to be pure, fresh (when possible) wild fish and other seafood, and free range chicken and turkey that are hormone and antibiotic free. Our carbohydrates need to be fresh fruits and vegetables, preferably organic. And we need good fats, such as those found in salmon, sardines and other cold-water fish, extra virgin olive oil, nuts, seeds, avocado, and acai (a Brazilian berry whose fatty-acid ratio resembles that of olive oil). These "good" fats will help us absorb nutrients from our vegetables and fruits, keep our cells supple, our skin glowing and wrinkle-free, our brains sharp, and our mood upbeat. We also need dietary fat to burn fat.

    By upsetting the delicate balance with extreme fad diets and ridiculous concepts, whether it is no-carb or no-fat or whatever, we create ongoing physical and mental health problems, including obesity, accelerated aging, and wrinkling, sagging skin. It is no coincidence that the rise of antidepressants such as Prozac occurred during the nonfat food craze of the 1980s--after all, our brains are comprised mainly of fat, and when we starve our brains of valuable nutrients, we become depressed. Salmon, with its rich complement of essential fatty acids, has been shown to be an excellent treatment for depression. Some studies have shown that it is more effective than powerful drugs in treating depression--without the side effects (moderate regular exercise is also great for depression--especially when combined with the salmon-rich anti-inflammatory diet).

    Our goal is to strive for balance, and to use common sense when planning a meal.

    Ava's transformation (see Ava's story on the following page) was, to say the least, impressive. If you follow the Perricone Weight-Loss Diet, you too can have impressive results.

    But how does it all really work? The next several chapters will explain the science behind my revolutionary concepts, and how you can make them work for you.

    Chapter 2

    The Inflammation-Aging-

    Disease-Obesity Connection

    One's mind, once stretched by a new idea,

    never regains its original dimensions.

    --Oliver Wendell Holmes

    As many readers of my earlier books know, the original anti-inflammatory diet is both a powerful antiaging, disease-fighting tool and the secret to clear, wrinkle-free skin. It was not specifically designed for weight loss. However, once I realized that people who needed to lose weight were rapidly losing it on this eating plan, I recognized a whole new world of potential for the overweight man or woman--whether he or she needed to shed a mere 10 pounds or was morbidly obese.

    I altered and adapted the original anti-inflammatory diet to focus on the specific foods and supplements that were proven to accelerate healthy weight loss while maintaining muscle mass. In fact, the anti-inflammatory weight-loss diet in this book closely parallels the very diet that I follow on a daily basis. The recommended foods will not only enable you to quickly drop excess weight, you will find increased energy, and an increased sense of mental well-being. When we realize that most dieters are subject to chronic crankiness, this is good news indeed.

    In this book, you are going to learn some surprising facts--facts that actually startled the scientific community when they were first discovered. You are going to learn that excess body fat is a living, breathing, multiplying endocrine organ--and that fact alone ensures that the fatter you are, the fatter you will get. This book is going to change your ideas about weight gain and weight loss. It is not about your daily intake of fat--and it is not about cutting out the carbs. It is about something no other book has ever explained: the connection between inflammation and body fat (and the fact that one is never present without the other). You will learn what foods cause this inflammation, and how to decrease and prevent it, thereby permanently eliminating all weight problems.


    Let's take a look at what I mean by inflammation. Inflammation, which is the response of the body's immune system to infection or irritation, exists in a very wide spectrum. At the extreme end it causes visible redness and swelling, such as in sunburn or an injured finger. On the low end of the spectrum, the inflammation is invisible; we can't see it and we can't feel it. But it does exist, and it causes a host of health-related problems. The bright red and painful sunburn that exists at the extreme high end is usually only present for a short period of time. Physicians refer to this type of inflammation as "acute inflammation." The invisible inflammation that exists at the low end of the spectrum is usually present for longer periods of time and is termed "chronic inflammation."

    The question you may be asking is, "If it is invisible, and we can't feel it, then how do we know that this low-grade inflammation exists?" The answer is simple: some of this inflammation can be detected under the microscope. However, low-grade inflammation can also be invisible even with a microscope because it exists on a molecular level, but it can be detected through chemical tests using special instruments.

    Research indicates that the effects of this chronic, low-grade, invisible inflammation is at the basis of aging and age-related diseases such as cardiovascular disease, diabetes, certain forms of cancer, Parkinson's, Alzheimer's, and autoimmune diseases--and even wrinkled, sagging skin.

    However, it doesn't stop there. I am now categorically stating that this same chronic, low-grade, invisible inflammation is at the very basis of excess body fat, out-of-control appetites, food cravings, food addictions, diabetes, and the inability to lose excess body weight.

    If that is the case, you may be thinking, "Why don't I just go ahead and take an ibuprofen tablet and get thin?" Unfortunately it is not that simple--especially when you consider this inflammation is not just a one-time event reacting to a one-time cause. Our bodies are under a constant barrage, a continual assault of physical insults resulting in this inflammation--beginning with that bag of potato chips and ending with the creation of a veritable factory in our body whose one job is to grow more fat cells and produce more inflammatory chemicals.

    The answer lies in learning to recognize and avoid the factors that are creating the inflammation in the first place, and then, through natural means, reducing the existing inflammation to successfully lose the excess body fat. By embracing the anti-inflammatory diet and lifestyle, you will not only lose the weight, you will dramatically alter your quality of life--and increase your life expectancy.

    The effect of this low-grade, invisible inflammation (also referred to as "subclinical" inflammation) has been at the cutting edge of medical science for the last decade, and it has been the focal point of my own research for the past two decades. After years of either being ignored or relegated to a "by-product" of the disease process, cellular inflammation is finally coming to the attention of the mainstream media, and in fact, was the topic of a cover story in Time magazine.


    Acute inflammation is a protective response of tissue to irritation, injury, or infection, and is characterized by pain, redness, swelling, and sometimes loss of function. It is, under normal circumstances, beneficial, and helps the body repair the effects of trauma or infection. However, prolonged, excess, or chronic inflammation becomes harmful.

    When low-grade invisible inflammation occurs in the very cells that comprise our organ systems, a concept I introduced in my first book, The Wrinkle Cure (2000), we are placed at great risk for a host of degenerative, age-related diseases. This is because cells that are attacked by self-generated inflammation will not function properly (meaning that we did something to precipitate a pro-inflammatory response in our cells, thus causing malfunction and sometimes complete breakdown).

    In other words, cells respond to the way we treat them. If we keep them healthy and free of injury, if we give them the proper nourishment, they keep us alive and running at top form.


    Excerpted from The Perricone Weight-Loss Diet by Nicholas Perricone, M.D. Excerpted by permission.
    All rights reserved. No part of this excerpt may be reproduced or reprinted without permission in writing from the publisher.
    Excerpts are provided by Dial-A-Book Inc. solely for the personal use of visitors to this web site.

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    The Perricone Weight-Loss Diet 2.8 out of 5 based on 0 ratings. 12 reviews.
    Guest More than 1 year ago
    The author presents some valid points about nutrition and the diet might bring expected results. However I have four major problems with the book: 1. There are a lot of blank spaces at every third or fourth page. I had the impression that this was made on purpose to have the book seem to contain much more info than it in fact does. I'm sure that without all the wasted space the book would contain less than 200 pages instead of over 300 pages 2. I think this is practically fourth book by the same author, saying more or less the same. There are a lot of receipes, which makes the impression of being a cook book rather than anythning else. 3. It seems to be geared towards naive but affluent people who do not mind paying triple prices for supplements that are available in other places at much lower prices 4. I have problem subscribing to the concept of unnoticeable inflammation developing in your body - an inflammation that you cannot see or feel... If I cannot see or feel it, why would I believe someone that tells me that the inflammation is there, and that I need to buy his supplements to fight it? I'm sorry but if I feel great I am not going to buy any pills to swallow just in case some new, unverified theory is right. Overall I would not give more than 3.5 stars for it, but since there is no such option, I am being generous by giving it 4 stars.
    Guest More than 1 year ago
    I thought the book was good until I realized I was reading an infomercial for Perricone weight loss formula to the tune of $190.00 per month.
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    Guest More than 1 year ago
    Dr Perricone teaches a 3-part program that works wonder on your skin and weight. I have using it now for about a month in a half and notice changes with the way I feel and look at the age of 44 years young! Thankyou Dr Perricone for offering such a wonderful way to stay healthy and feeling better about yourself.