The Promise of Low Dose Naltrexone Therapy: Potential Benefits in Cancer, Autoimmune, Neurological and Infectious Disorders

The Promise of Low Dose Naltrexone Therapy: Potential Benefits in Cancer, Autoimmune, Neurological and Infectious Disorders

by Elaine A. Moore, Samantha Wilkinson
     
 

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ISBN-10: 0786437154

ISBN-13: 9780786437153

Pub. Date: 12/01/2008

Publisher: McFarland & Company, Incorporated Publishers

Naltrexone is an opiate antagonist drug developed in the 1970s and approved by the FDA in 1984 for opiate and drug abuse treatment. When used at much lower doses in an off-label protocol referred to as low dose naltrexone (LDN), the drug has been shown to halt disease progression in Crohn's disease and certain cancers, to reduce symptoms in multiple sclerosis and

Overview

Naltrexone is an opiate antagonist drug developed in the 1970s and approved by the FDA in 1984 for opiate and drug abuse treatment. When used at much lower doses in an off-label protocol referred to as low dose naltrexone (LDN), the drug has been shown to halt disease progression in Crohn's disease and certain cancers, to reduce symptoms in multiple sclerosis and autism, and to improve numerous autoimmune and neurodegenerative conditions, including Parkinson's disease and amyotrophic lateral sclerosis (ALS).

Grounded in clinical and scientific research, this book describes the history of naltrexone, its potential therapeutic uses, its effects on the immune system, its pharmacological properties, and how the drug is administered. It also lists fillers and compounding pharmacies, doctors who prescribe LDN, and patient resources, and includes interviews with LDN patients and researchers.

Product Details

ISBN-13:
9780786437153
Publisher:
McFarland & Company, Incorporated Publishers
Publication date:
12/01/2008
Series:
McFarland Health Topics
Pages:
223
Product dimensions:
5.90(w) x 8.90(h) x 0.60(d)

Related Subjects

Table of Contents

Acknowledgments vi

Foreword Yash Pal Agrawal, M.D., Ph.D. 1

Preface 5

Introduction 7

1 The War on Drugs-A History of Naltrexone 11

2 LDN in Autoimmune Diseases 29

3 LDN in Multiple Sclerosis 45

4 LDN in Neurodegenerative Disorders 61

5 LDN in Cancer 78

6 LDN in Autism Spectrum Disorders 95

7 LDN in Wound Healing and Infections 102

8 The Immune System and LDN in HIV/AIDS 108

9 The LDN Experience: A Patient's Guide to LDN 126

10 The Potential Benefits and Future of LDN 148

Chapter Notes 159

Glossary 167

Appendix Clinical Trials of LDN and Related Compounds 179

Resources 189

Index 209

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