The Psychosis-Risk Syndrome: Handbook for Diagnosis and Follow-Up / Edition 1

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Using the authors' over thirteen years of experience at the psychosis-risk clinic at Yale University School of Medicine, The Psychosis-Risk Syndrome presents a concise handbook that details the diagnostic tools and building blocks that comprise the Structural Interview for Psychosis-Risk Syndromes, or SIPS. Clear and to the point, this volume provides an in-depth description of this new clinical high-risk population, along with instructions on how to use the SIPS to evaluate persons for psychosis-risk.

The handbook's main section takes the reader step-by-step through the SIPS evaluation, tracking how patients and families find their way to the clinic, the initial interview, the evaluation process, and the summary session consisting of findings and future options. The core diagnostic symptoms of the SIPS and psychosis-risk states are illustrated with dozens of symptom and case examples drawn from real but disguised patients from the Yale clinic. With an emphasis on clinical usefulness, the handbook finishes with "practice cases" for the reader to test his or her new skills at evaluating clinical populations for psychosis-risk.

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Editorial Reviews

Doody's Review Service
Reviewer: Michael Joel Schrift, DO, MA (University of Illinois at Chicago College of Medicine)
Description: It is quite unfortunate that with the advances in the neurosciences and progress on the understanding of how the brain works that this knowledge has not really affected how we diagnosis or really treat mental illness. The diagnosis of chronic psychosis such as schizophrenia is still based just on clinical symptom recognition and, as the authors of this book correctly point out, once symptoms are detected the illness is already there. This is a clinical handbook on detecting those individuals at risk for developing psychosis based on the model used at the Connecticut Mental Health Center in New Haven.
Purpose: The purpose is to convey what the authors have learned about these syndromes of psychosis risk and how to identify them for research and treatment.
Audience: The target audience includes psychiatrists, psychologists, and social workers involved in the care and treatment of patients as well as in the prevention of psychosis. Written and edited by authorities in the field, this book is a welcome addition to the psychiatric literature.
Features: The first part of the book reviews the history of the concept of first-break psychosis, the development of the assessment tools with reliability and validity data, symptom classes, the risk syndromes and psychosis, negative symptoms, and characteristics of the risk samples. The next section focuses on the step-by-step process used at their clinic in patient evaluation with the final section reviewing their experience in this clinic. The bibliography contains important references to the relevant literature and appendixes cover phone screening for risk syndrome, structured interviews for psychosis-risk syndromes, and the informed consent document.
Assessment: This is a valuable new tool in the effort to detect individuals at risk for psychosis. It provides keen insights into developing similar detection programs.
From the Publisher
"This is a valuable new tool in the effort to detect individuals at risk for psychosis. It provides keen insights into developing similar detection programs." —Doody's
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Product Details

  • ISBN-13: 9780199733316
  • Publisher: Oxford University Press, USA
  • Publication date: 6/3/2010
  • Edition number: 1
  • Pages: 256
  • Product dimensions: 6.00 (w) x 9.40 (h) x 1.00 (d)

Meet the Author

Thomas H. McGlashan MD, Founder, PRIME Research Clinic, Professor, Department of Psychiatry, Yale University, New Haven, CT, USA

Barbara Walsh PhD, Clinical Coordinator, PRIME Research Clinic, Department of Psychiatry, Yale University, New Haven, CT, USA

Scott Woods MD, Director, PRIME Research Clinic, Department of Psychiatry, Yale University, New Haven, CT, USA

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Table of Contents

PART A: Psychosis-Risk Syndromes for First Psychosis: Background 1
1. Psychosis-Risk Syndromes for First Psychosis: A History of the Concept 3
2. Development of the Structured Interview for Psychosis-Risk Syndromes (SIPS) 10
3. Reliability and Validity of the SIPS 17
4. Symptom Classes and Factors in the SIPS 21
5. Psychosis-Risk Syndromes and Psychosis in the SIPS 24
6. The "Other" Symptoms of the Risk Syndromes: Negative, Disorganization, and General 33
7. Characteristics of SIPS Psychosis-Risk Samples 36

PART B: Psychosis-Risk Syndromes: SIPS and SOPS Evaluation 45
8. Pathways to the Risk Syndrome Clinic 47
9. Initial Interview: The SIPS and SOPS Evaluation 49
10. Initial Evaluation: Informing Patients and Families of Risk Status and Options 59
11. Rating Positive and Other Psychosis-Risk Symptoms with the SOPS 63
12. Rating Actual Cases, Baseline Assessment 78
13. Differential Diagnosis of the Psychosis-Risk Syndrome 109
14. Psychosis-Risk Patients over Time 120
15. Rating Baseline Cases for Practice 139

PART C: The PRIME Clinic: Psychosis-Risk Patients Face-to-Face 161
Bibliography 169
A. Risk Syndrome Phone Screen 174
B. SIPS/SOPS 5.0 179
C. Informed Consent 237

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