The Spinal Cord: A Christopher and Dana Reeve Foundation Text and Atlas

The Spinal Cord: A Christopher and Dana Reeve Foundation Text and Atlas

by Charles Watson, Claire Heise
     
 

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ISBN-10: 0123742471

ISBN-13: 9780123742476

Pub. Date: 11/26/2008

Publisher: Elsevier Science

Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of

Overview

Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of nervous tissue in the spine to regenerate has increasingly been on the forefront of biomedical research in the past years. The Spinal Cord, a collaboration with the Christopher and Dana Reeve Foundation, is the first comprehensive book on the anatomy of the mammalian spinal cord. Tens of thousands of articles and dozens of books are published on this subject each year, and a great deal of experimental work has been carried out on the rat spinal cord. Despite this, there is no comprehensive and authoritative atlas of the mammalian spinal cord. Almost all of the fine details of spinal cord anatomy must be searched for in journal articles on particular subjects. This book addresses this need by providing both a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords in one convenient source. The book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations from the leading experts in the field and atlases of the rat and the mouse spinal cord. The rat and mouse spinal cord atlas chapters include photographs of Nissl stained transverse sections from each of the spinal cord segments (obtained from a single unfixed spinal cord), detailed diagrams of each of the spinal cord segments pictured, delineating the laminae of Rexed and all other significant neuronal groupings at each level and photographs of additional sections displaying markers such as acetylcholinesterase (AChE), calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), enkephalin, calcitonin gene-related peptide (CGRP), and neuronal nuclear protein (NeuN).

The text provides a detailed account of the anatomy of the mammalian spinal cord and surrounding musculoskeletal elements.
The major topics addressed are:

• development of the spinal cord

• the gross anatomy of the spinal cord and its meninges

• spinal nerves, nerve roots, and dorsal root ganglia

• the vertebral column, vertebral joints, and vertebral muscles

• blood supply of the spinal cord

• cytoarchitecture and chemoarchitecture of the spinal gray matter

• musculotopic anatomy of motoneuron groups

• tracts connecting the brain and spinal cord

• spinospinal pathways

• sympathetic and parasympathetic elements in the spinal cord

• neuronal groups and pathways that control micturition

• the anatomy of spinal cord injury in experimental animals

The atlas of the rat and mouse spinal cord has the following features:

• Photographs of Nissl stained transverse sections from each of 34 spinal segments for the rat and mouse.

• Detailed diagrams of each of the 34 spinal segments for rat and mouse, delineating the laminae of Rexed and all other significant neuronal groupings at each level.

• Alongside each of the 34 Nissl stained segments, there are additional sections displaying markers such as acetylcholinesterase, calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), and neuronal nuclear protein (NeuN).

• All the major motoneuron clusters are identified in relation to the individual muscles or muscle groups they supply.

Product Details

ISBN-13:
9780123742476
Publisher:
Elsevier Science
Publication date:
11/26/2008
Pages:
408
Product dimensions:
8.80(w) x 11.10(h) x 1.10(d)

Table of Contents

THE SPINAL CORD - A CHRISTOPHER AND DANA REEVE FOUNDATION TEXT AND ATLAS

Charles Watson, George Paxinos and Gulgun Kayalioglu (editors)

Chapter 1 The organization of the spinal cord Charles Watson, Curtin University of Technology and Gulgun Kayalioglu, Ege University) Chapter 2 Development of the spinal cord (Ken WS Ashwell, The University of New South Wales) Chapter 3 The vertebral column and the spinal meninges (Gulgun Kayalioglu, Ege University) Chapter 4 The spinal nerves (Gulgun Kayalioglu, Ege University) Chapter 5 The spinal cord blood vessels (Oscar U Scremin, UCLA) Chapter 6 Cytoarchitecture of the spinal cord (Claire Heise, Prince of Wales Medical Research Institute and Gulgun Kayalioglu, Ege University) Chapter 7 Localization of motoneurons in the spinal cord (Steve McHanwell, University of Newcastle UK and Charles Watson, Curtin University of Technology) Chapter 8 Spinal autonomic preganglionic neurons: the visceral efferent system of the spinal cord (Colin R Anderson, University of Melbourne, Janet R Keast, Kolling Institute, University of Sydney at Royal North Shore Hospital, and Elspeth M McLachlan, Prince of Wales Medical Research Institute) Chapter 9 Central nervous system control of micturition (Gert Holstege, University of Groningen and Han Collewijn, Erasmus University Medical Center) Chapter 10 Projections from the spinal cord to the brain (Gulgun Kayalioglu, Ege University) Chapter 11 Projections from the brain to the spinal cord (Charles Watson, Curtin University of Technology and Alan R Harvey, University of Western Australia) Chapter 12 The propriospinal system (Amanda C Conta and Dennis J Stelzner, SUNY Upstate Medical University) Chapter 13 Spinal cord transmitter substances (Claire Heise, Prince of Wales Medical Research Institute and Gulgun Kayalioglu, Ege University) Chapter 14 Spinal cord injury: experimental animal models and relation to human therapy (Stuart I Hodgetts, Giles W Plant, and Alan R Harvey, University of Western Australia) Chapter 15 An atlas of the mouse spinal cord (Charles Watson, George Paxinos, Gulgun Kayalioglu, and Claire Heise) Chapter 16 An atlas of the rat spinal cord (Charles Watson, George Paxinos, Gulgun Kayalioglu, and Claire Heise) Chapter 17 Toward a spinal cord ontology (Charles Watson and Amandeep Sidhu, Curtin University of Technology)

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