The Threat of Pandemic Influenza: Are We Ready? Workshop Summary

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Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns.

The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.

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Product Details

  • ISBN-13: 9780309095044
  • Publisher: National Academies Press
  • Publication date: 3/11/2005
  • Pages: 432
  • Product dimensions: 6.12 (w) x 9.08 (h) x 0.96 (d)

Table of Contents

1918 revisited : lessons and suggestions for further inquiry 58
Chasing the elusive 1918 virus : preparing for the future by examining the past 69
Pandemic influenza and mortality : past evidence and projections for the future 89
Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in Eastern Asia 115
Avian influenza outbreak in Thailand : current policies 127
The 2003-2004 H5N1 avian influenza outbreak in Vietnam 130
WHO consultation on priority public health interventions before and during influenza pandemic executive summary 144
Pandemic influenza preparedness and response plan 154
Considerations for pandemic influenza planning : a state perspective 168
Preparing for pandemic influenza : the need for enhanced surveillance 172
Preparedness opportunities and obstacles 177
Pandemic influenza vaccines : obstacles and opportunities 184
Statement from MedImmune, Inc., regarding reverse genetics technology 196
Perspectives on antiviral use during pandemic influenza 197
Partnering with the private medical system 212
Standards and activities of the OIE related to avian influenza 223
U.S. strategies for controlling avian influenza in agricultural systems 233
Low-pathogenicity avian influenza outbreaks in commercial poultry in California 243
Control of influenza virus infection by immunity to conserved viral features 254
Generation of transgenic chickens resistance to avian influenza virus 273
Molecular diagnostics in an insecure world 284
Modeling pandemic preparedness scenarios : health economic implications of enhanced pandemic vaccine supply 292
The economic impact of pandemic influenza in the United States : priorities for intervention 316
Increasing awareness and uptake of influenza immunization 339
Strategies to remedy panic in a pandemic : lessons from biodefense 347
Public health preparedness and ethical values in pandemic influenza 357
App Pandemic influenza : assessing capabilities for prevention and response 373
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