Therapeutic Microbiology: Probiotics and Related Strategies

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Overview

Breaks new ground in explaining the breakthroughs possible with therapeutic microbiology.

  • Explores the potential and actual uses of the many methods for altering the microbiotas of humans and animals: probiotics, prebiotics, synbiotics, bacteriophages, and replacement therapy.
  • Describes the biological principles underlying the manipulation of the indigenous microbiota and the biology of the effector organisms that have been utilized for this purpose.
  • Discusses the many microbes that can potentially be used therapeutically and prophylactically.
  • Serves as a reference to medical, dental and veterinary practitioners with an interest in alternative approaches to the prevention and treatment of microbial diseases.


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Editorial Reviews

Doody's Review Service
Reviewer: Rebecca T. Horvat, PhD, D (ABMM)(University of Kansas Medical Center)
Description: This unique book provides a scientific update on the use of probiotics and prebiotics as an antidote to human diseases. The use of probiotics is not a new concept but their use as specific therapy has recently gotten more attention from medicine and science and thus have become more widely accepted.
Purpose: The purpose is to provide a single reference that provides reliable information needed for scientists working in this new area of investigation. At the end of chapter 1, the purpose is stated as "consolidating the range of information available on how microbes can be useful to promote health and prevent or treat disease." It is clear that the book will be key for those interested in this developing research field.
Audience: This book is written for physicians treating patients, scientists investigating the micro flora of humans, and nutritionists investigating and treating patients with various metabolic and nutritional problems. This book could also be used by students. The chapters are written by highly respected scientists who have coordinated their efforts to provide a well integrated volume that will serve as a valuable resource for many years.
Features: The term "probiotic" is literally defined as supporting life, but in this context it refers to live bacterial agents that promote the health of the host. The other term used in this book, "prebiotic," has been defined as a food ingredient that beneficially affects the host by stimulating the growth or activity of certain valuable bacteria. Prebiotics are generally carbohydrates that are indigestible by humans. Of interest is the historical information that the use of probiotics and prebiotics is not new and has been documented in scientific and medical literature of the early 1900s. The book starts with describing the studies that have investigated probiotics. Many chapters are devoted to the description of the favorable bacterial species and how they work to keep humans healthy. Other chapters describe the substances that are used as prebiotics and how they have been investigated in humans and animals. The final chapters demonstrate the use of these agents in the treatment of specific diseases in humans and animals.
Assessment: This is a unique book that describes and discusses some key ingredients to good health and that is a healthy, balanced microbial system. I was greatly impressed with the scientific presentation of this material and the objectivity of the authors. I have gained great insight into the utility of this approach in treating diseases. I anticipate that this book will trigger further studies focusing on this approach.
From The Critics
Reviewer: Rebecca T. Horvat, PhD, D (ABMM)(University of Kansas Medical Center)
Description: This unique book provides a scientific update on the use of probiotics and prebiotics as an antidote to human diseases. The use of probiotics is not a new concept but their use as specific therapy has recently gotten more attention from medicine and science and thus have become more widely accepted.
Purpose: The purpose is to provide a single reference that provides reliable information needed for scientists working in this new area of investigation. At the end of chapter 1, the purpose is stated as "consolidating the range of information available on how microbes can be useful to promote health and prevent or treat disease." It is clear that the book will be key for those interested in this developing research field.
Audience: This book is written for physicians treating patients, scientists investigating the micro flora of humans, and nutritionists investigating and treating patients with various metabolic and nutritional problems. This book could also be used by students. The chapters are written by highly respected scientists who have coordinated their efforts to provide a well integrated volume that will serve as a valuable resource for many years.
Features: "The term "probiotic" is literally defined as supporting life, but in this context it refers to live bacterial agents that promote the health of the host. The other term used in this book, "prebiotic," has been defined as a food ingredient that beneficially affects the host by stimulating the growth or activity of certain valuable bacteria. Prebiotics are generally carbohydrates that are indigestible by humans. Of interest is the historical information that the use of probiotics and prebiotics is not new and has been documented in scientific and medical literature of the early 1900s. The book starts with describing the studies that have investigated probiotics. Many chapters are devoted to the description of the favorable bacterial species and how they work to keep humans healthy. Other chapters describe the substances that are used as prebiotics and how they have been investigated in humans and animals. The final chapters demonstrate the use of these agents in the treatment of specific diseases in humans and animals. "
Assessment: This is a unique book that describes and discusses some key ingredients to good health and that is a healthy, balanced microbial system. I was greatly impressed with the scientific presentation of this material and the objectivity of the authors. I have gained great insight into the utility of this approach in treating diseases. I anticipate that this book will trigger further studies focusing on this approach.
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Product Details

  • ISBN-13: 9781555814038
  • Publisher: ASM Press
  • Publication date: 7/1/2008
  • Edition description: New Edition
  • Pages: 420
  • Product dimensions: 8.70 (w) x 11.10 (h) x 1.00 (d)

Table of Contents

Table of Contents

1. INTRODUCTION

1 Introduction, Mary Ellen Sanders

2. BASIC BIOLOGY

2.1. The Indigenous Microbiota

2 Role of the Indigenous Microbiota in Health and Disease, Gerald W. Tannock

2.2. Biology of Effector Organisms for Probiotic and Replacement Therapy

3 Lactobacilli, Covadonga Barbés

4 Bifidobacteria: the Model Human Gut Commensal, Marco Ventura, Francesca Turroni, Angela Ribbera, Elena Foroni, and Douwe van Sinderen

5 Saccharomyces spp., Xinhua Chen and Ciarán P. Kelly

6 Streptococci as Effector Organisms for Probiotic and Replacement Therapy, John R. Tagg, Jeremy P. Burton, Philip A. Wescombe, and Chris N. Chilcott

7 Escherichia coli, Michael Schultz

8 Formulation, Administration, and Delivery of Probiotics, Kasipathy Kailasapathy

2.3. Prebiotics and Functional Carbohydrates

9 Introduction to Prebiotics, Helena M. R. T. Parracho, Delphine M. Saulnier, Anne L. McCartney, and Glenn R. Gibson

10 Human Milk Oligosaccharides as Prebiotics, Giovanni V. Coppa and Orazio Gabrielli

11 Inulin-Type Fructans, Jan Van Loo and Douwina Bosscher

12 Resistant Starch as a Prebiotic, Anthony R. Bird and David L. Topping

13 Effects of Prebiotic Supplementation on Bone Mineral Metabolism and Weight in Humans, Steven A. Abrams

14 Prebiotics and Lipid Metabolism, Nathalie M. Delzenne, Patrice D. Cani, and Audrey M. Neyrinck

2.4. Genomics of Lactic Acid Bacteria

15 Functional Genomics of Lactic Acid Bacteria, Tri Duong and Todd R. Klaenhammer

2.5. Proteomics of Lactic Acid Bacteria

16 Proteomic Approaches To Study Lactic Acid Bacteria, David P. A. Cohen, Elaine E. Vaughan, Willem M. de Vos, and Erwin G. Zoetendal

3. THERAPEUTIC MICROBIOLOGY IN HUMAN MEDICINE

3.1. Probiotics

17 Probiotics in Human Medicine: Overview, Jennifer K. Spinler and James Versalovic

18 Probiotics and Other Organisms in Allergy and Autoimmune Diseases, G. A. W. Rook and Nina Witt

19 Probiotics in Oral Biology and Dentistry, J. H. Meurman

20 Probiotics in Gastrointestinal Diseases, Francisco Guarner

21 Probiotics and Diseases of the Genitourinary Tract, Gregor Reid

22 Probiotics in Neurology and Psychiatry, Paul Forsythe and John Bienenstock

3.2. Prebiotics

23 Prebiotics in Human Medicine, Ian Rowland

3.3. Synbiotics

24 Synbiotics in Human Medicine, Stig Bengmark

4. THERAPEUTIC MICROBIOLOGY IN VETERINARY MEDICINE

25 Strategies for Altering the Intestinal Microbiota of Animals, Sergey R. Konstantinov and Jerry Wells

26 Probiotics in Veterinary Medicine, J. Scott Weese, Shayan Sharif, and Alex Rodiguez-Palacios

27 Prebiotics and Synbiotics in Companion Animal Science, David Hernot, Eva Ogué, George Fahey, and Robert A. Rastall

5. VIRAL STRATEGIES

28 Phage Therapy, Mikael Skurnik, Saija Kiljunen, and Maria Pajunen

6. FUTURE PROSPECTS

29 The Road Ahead: a Look at the Future, James Versalovic and Michael Wilson

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