Therapeutic Uses of Botulinum Toxin / Edition 1

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Therapeutic Uses of Botulinum Toxin outlines and examines our current understanding of botulinum toxin and its various therapeutic applications. The editors explore how this novel compound fits into a wide variety of treatment algorithms across medical subspecialties. Each chapter focuses on a particular symptom and adn explains how botulinum toxin is curently used for treatment . Physicians will benfit not only from those chapters devoted to their particular subspecialty, but from the inspiring success resulting for the useof botulinum toxin in other patient populations. The concluding chapter examines questions of immunity, explores economic issues, and attempts to forecast future directions for this novel and somewhat mysterious drug. Clinicians acrosss a wide variety of disciplines will refer to this comprehensive reference time and time again.

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Editorial Reviews

Doody's Review Service
Reviewer: Ross Bogey, DO (Rehabilitation Institute of Chicago)
Description: This book presents many of the clinical uses of the relatively new drug, botulinum toxin. Several of the chapters are excellent, particularly the review of mechanism of action and applicability in the treatment of spasticity, pain, sialorrhea and blepherospasm. However, the book attempts to cover nearly all uses of the medication known to the assorted authors, including potential treatments for which there is little peer-reviewed literature.
Purpose: The purpose is to provide an overview of this medication, and present clinical scenarios in which the drug might be an appropriate choice. However, the scope is too broad and many of the potential treatments are poorly supported by the available literature.
Audience: The target audience should be clinicians (physicians and therapists) with an introductory knowledge of how to use this drug. One concerning aspect of the book is the relative inexperience of the contributing authors. Nearly one-third are resident physicians, and the expertise of several of the staff physicians cannot be determined from their biographies or publication records.
Features: The best parts of the book are the chapters related to well described conditions treatable with botulinum toxins: spasticity, pain, headache, hyperhydrosis, and blepherospasm. The chapter on mechanism of action is particularly well written. The greatest shortcoming is in the parts devoted to treatment of conditions where there is little peer-reviewed evidence that treatment with botulinum toxins is beneficial; one example is treatment of plantar fascitis. The authors' description of their respective injection techniques would be better served in a workshop environment.
Assessment: Most of the relevant ideas in this book can be found easily via web sites devoted to treatment of movement disorders or spasticity (e.g.,
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Product Details

  • ISBN-13: 9781617378423
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 9/8/2011
  • Series: Musculoskeletal Medicine Series
  • Edition description: Softcover reprint of hardcover 1st ed. 2007
  • Edition number: 1
  • Pages: 238
  • Product dimensions: 7.00 (w) x 10.00 (h) x 0.53 (d)

Table of Contents


Chapter 1: History and Mechanism of Action
Zinovy Meyler, DO, Grant Cooper, MD

Chapter 2: Spasticity
Elise Weiss, MD, David Lin, MD

Chapter 3: Radiation Fibrosis Syndrome Applications - Trismus, Trigeminal Neuralagia, and Cervical Dystonia
Michael Stubblefield, MD

Chapter 4: Back Pain
Rebecca Brown, MD*, Avniel Klein MD*, Alex Visco, MD, Joseph E. Herrera, DO
*These authors contributed equally and are co-first authors. Note to Humana — If this is ever done, do this. Otherwise, just make Rebecca the first author. Thanks.

Chapter 5: Piriformis Syndrome
Loren M. Fishman, MD, Alena Polesin, MD, Steven Sampson, DO

Chapter 6: Plantar Fasciitis
Mary S. Babcock DO
Chapter 7: Headache
Jerome S. Schwartz, MD, Phillip Song, MD, Andrew Blitzer, MD, DDS
Chapter 8: Spasmodic Dysphonia
Jerome S. Schwartz, MD, Phillip Song, MD, Andrew Blitzer, MD, DDS
Chapter 9: Sialorrhea and Frey's Syndrome.
Phillip C. Song, MD, Jerome Schwartz, MD, and Andrew Blitzer, MD. DDS.

Chapter 10: Cosmetic Applications
Tara D. Miller, MD, Isaac M. Neuhaus, MD
Chapter 11: Hyperhidrosis
Joely Kaufman, MD, FAAD, Leslie Baumann, MD, FAAD

Chapter 12: Urologic Applications
David E. Rapp, MD, Gregory T. Bales, MD
Chapter 13: Gastrointestinal Applications: Achalasia, Gastroparesis, and Anal Fissure

Shayan Irani, MD, Frank Friedenberg, MD
Chapter 14: Blepharospasm
Amir Cohen, MD, MBA, Marc J. Spirn, MD, David Khoramian, BA,
and C. Robert Bernardino MD
Chapter 15: Economics, Immunity, and Future Directions
Victoria Chan Harrison, MD, David Lin, MD

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