Therapy for Genetic Disease

Therapy for Genetic Disease

by Theodore Friedmann
     
 


The biochemical and genetic understanding of human disease has increased explosively in recent years. We now understand that most human disease is the result of interactions between genetic factors and environmental influences, and the combined influences are being identified in our society's most important and burdensome diseases, including cancer, diabetes, and…  See more details below

Overview


The biochemical and genetic understanding of human disease has increased explosively in recent years. We now understand that most human disease is the result of interactions between genetic factors and environmental influences, and the combined influences are being identified in our society's most important and burdensome diseases, including cancer, diabetes, and degenerative disorders such as arthritis, Alzheimer's and Parkinson disease. When mutant genes combine with environmental factors to produce a cascade of malfunctions, treatment may take one of many different approaches. This book describes the range of disorders and the treatments which have become available for them as a result of our increased understanding. These treatments range from classical approaches such as the supply of a missing product of enzyme activity, through enzyme or cofactor replacement, to the exciting possibility of therapy directed specifically to the underlying defect, the mutant gene itself.

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Product Details

ISBN-13:
9780192619716
Publisher:
Oxford University Press, USA
Publication date:
08/01/1991
Series:
Molecular Medicine Series
Pages:
144
Product dimensions:
6.06(w) x 9.19(h) x 0.37(d)

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Meet the Author

UCSD School of Medicine, La Jolla, California

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