Therapy for Mucus-Clearance Disorders

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Overview

This single-source reference provides an up-to-date exploration of current medications and devices used for the clearance of mucus from the lungs while simultaneously providing the latest research and studies to clearly guide scientists studying the pathophysiology of airway inflammation and mucus clearance, clinicians and therapists treating patients with chronic lung disease, and researchers developing new medications and devices to enhance airway clearance.
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Overview

This single-source reference provides an up-to-date exploration of current medications and devices used for the clearance of mucus from the lungs while simultaneously providing the latest research and studies to clearly guide scientists studying the pathophysiology of airway inflammation and mucus clearance, clinicians and therapists treating patients with chronic lung disease, and researchers developing new medications and devices to enhance airway clearance.
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Product Details

Table of Contents

Introduction
1 Overview of airway mucus clearance 1
2 The biophysical properties of mucus 29
3 Regulation of airway mucus secretion 43
4 Outcomes for trials of mucoactive therapy 87
5 Adherence with the use of clearance techniques 105
6 Taxonomy of mucoactive medications 129
7 Mucoactive drug delivery 147
8 Expectorants 175
9 Mucolytics and mucus clearance 201
10 Modulation of mucociliary function by drugs and other agents 225
11 Mucokinetic agents and surfactant 307
12 Mucoregulatory medications 327
13 Hyperosmolar solutions and ion channel modifiers 353
14 Mucoactive agents and the upper airway 373
15 Issues on regulatory approval of mucoactive drugs 395
16 Airway-clearance techniques individually tailored to each patient 413
17 High-frequency oscillation, PEP, and flutter 433
18 Pediatric mucus clearance by chest physiotherapy : principles and practice 471
19 Postoperative mucus clearance 503
20 Management of airway secretions in patients with severe respiratory muscle dysfunction 553
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