BN.com Gift Guide

This is not available 019175

Paperback (Print)
Not Available on BN.com
 

More About This Textbook

Overview

Feedback is an ubiquitous feature of neural systems though there is little consensus on the roles of mechanisms involved with feedback. We set up an in vivopreparation to study and characterize an accessible and isolated feedback loop within the visual system of the leopard frog, Rana pipiens. We recorded extracellularly within the nucleus isthmi, a nucleus providing direct topographic feedback to the optic tectum, a nucleus that receives the vast majority of retinal output. The optic tectum and nucleus isthmi of the amphibian are homologous structures to the superior colliculus and parabigeminal nucleus in mammals, respectively. We formulated a novel threshold for detecting neuronal spikes within a low signal-to-noise environment, as exists in the nucleus isthmi due to its high density of small neuronal cell bodies. Combining this threshold with a recently developed spike sorting procedure enabled us to extract simultaneous recordings from up to 7 neurons at a time from a single extracellular electrode. We then stimulated the frog using computer driven dynamic spatiotemporal visual stimuli to characterize the responses of the nucleus isthmi neurons. We found that the responses display surprisingly long time courses to simple visual stimuli. Furthermore, we found that when stimulated with complex contextual stimuli the response of the nucleus isthmi is quite counter-intuitive. When a stimulus is presented outside of the classical receptive field along with a stimulus within the receptive field, the response is actually higher than the response to just a stimulus within the classical receptive field. Finally, we compared the responses of all of the simultaneously recorded neurons and, together with data from in vitro experiments within the nucleus isthmi, conclude that the nucleus isthmi of the frog is composed of just one electrophysiological population of cells.
Read More Show Less

Product Details

  • ISBN-13: 9781243641915
  • Publisher: BiblioLabsII
  • Publication date: 9/6/2011
  • Pages: 192
  • Product dimensions: 8.00 (w) x 10.00 (h) x 0.50 (d)

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)