The present experiments explored the viability of a protocol involving artificial selection for recovery from cSNC across three selected generations. Preliminary evidence for the effects of selective breeding for the fast (H line), when compared to the slow (L line) and random (R line) lines, was reported. In addition, consistent changes in other behavioral tests were found exclusively for the H line during the third generation. Rats in the H strain showed smaller body size, lower water consumption, and less sensitivity for different sucrose solutions than rats in the other two strains. Moreover, animals in the H strain showed a different activity profile, with lower activity levels in the early portion of the session. Finally, autoshaping acquisition and extinction were slower for rats in the H line when compared to rats in the L and R lines.