Tissue Engineering of Cartilage and Bone / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
$172.46
Used and New from Other Sellers
Used and New from Other Sellers
from $153.86
Usually ships in 1-2 business days
(Save 27%)
Other sellers (Hardcover)
  • All (8) from $153.86   
  • New (6) from $167.47   
  • Used (2) from $153.86   

Overview

Tissue engineering takes advantages of the combined use of cultured living cells and three-dimensional scaffolds to reconstruct adult tissues that are absent or malfunctioning. This book brings together scientists and clinicians working on a variety of approaches for regenerating of damaged or lost cartilage and bone to assess the progress of this dynamic field.

In its early days, tissue engineering was driven by material scientists who designed novel bio-resorbable scaffolds on which to seed cells and grow tissues. This ground-breaking work generated high expectations, but there have been significant stumbling blocks holding back the widespread use of these techniques in the clinic. These challenges, and potential ways of overcoming them, are given thorough coverage in the discussions that follow each chapter.

The key questions addressed in this book include the following. How good must cartilage repair be for it to be worthwhile? What is the best source of cells for tissue engineering of both bone and cartilage? Which are the most effective cell scaffolds? What are the best preclinical models for these technologies? And when it comes to clinical trials, what sort of outcome measures should be used? With contributions from some of the leading experts in this field, this timely publication will prove essential reading for anyone with an interest in the field of tissue engineering.

Read More Show Less

Editorial Reviews

From the Publisher

"…an excellent source of information…provides a valuable insight into the present and future strategies for bone and tissue engineering." (Annals of Biomedical Engineering, February 2004)

"…an excellent source of information…provides valuable insight into the present and future strategies for bone and tissue engineering" (Annals of Biomedical Engineering, Issue 32:02)

"...I found this book to be an excellent publication for researchers already engaged in the field of tissue engineering". (The Biochemist, 10 July 2003)

“…successfully sets about translating bone and cartilage tissue engineering principles into a clinically relevant science…” (The Newsletter of the British Society of Cell Biology, Summer 2005)

Read More Show Less

Product Details

  • ISBN-13: 9780470844816
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 4/22/2003
  • Series: Novartis Foundation Symposia Series , #197
  • Edition number: 1
  • Pages: 262
  • Product dimensions: 6.12 (w) x 9.26 (h) x 0.69 (d)

Table of Contents

Chair's Introduction (A. Caplan).

Tissue engineering of cartilage: do we need it, can we do it, is it good and can we prove it? (L. Lohmander).

Embryonic development and the principles of tissue engineering (A. Caplan).

The fundamentals of tissue engineering: scaffolds and bioreactors (G. Vunjak-Novakovic).

Tissue-engineered versus native cartilage: linkage between cellular mechano-transduction and biomechanical properties (J. Lee, et al.).

From the preclinical model to the patient (E. Hunziker).

Mesenchymal stem cell therapy in joint disease (F. Barry).

Differentiated chondrocytes for cartilage tissue engineering (J. Huckle, et al.).

Mesenchymal stem cells and bioceramics: strategies to regenerate the skeleton (H. Ohgushi, et al.).

Bone marrow stromal cells and their use in regenerating bone (R. Cancedda, et al.).

Studying the effect of different macrostructures on in vitro cell behaviour and in vivo bone formation using a tissue engineering approach (R. Dekker, et al.).

General discussion I

Cartilage repair with chondrocytes: clinical and cellular aspects (A. Lindahl, et al.).

Qualitative and quantitative in vivo assessment of articular cartilage using magnetic resonance imaging (E. O'Byrne, et al.).

Hyaluronan-based scaffolds (Hyalograft® C) in the treatment of knee cartilage defects: preliminary clinical findings (A. Pavesio, et al.).

Quantitative analysis of repair tissue biopsies following chondrocyte implantation (A. Hollander, et al.).

General discussion II: Tissue engineering using recombinant human BMP2.

Final discussion and summing-up.

Index of contributors.

Subject index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)