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From The CriticsReviewer: Eric M. Scholar, PhD(University of Nebraska Medical Center)
Description: This book provides information on topical antimicrobial therapy for professionals working in this area.
Purpose: The purpose is to provide the reader with the rationale and the statistical designs most appropriate for evaluating topical antimicrobial efficacy.
Audience: It is intended for technicians, scientists, and students who work in this area. The author is well qualified as a result of his extensive experience in industry and academia.
Features: This book begins with a general approach to developing topical antimicrobials and then provides an examination of the skin environment and properties of bacteria. The author then discusses the most common topical antimicrobials followed by the basic experimental designs needed to evaluate these drugs and concludes with a discussion of the basic statistical designs used in this field. The most recent information in the field of topical antimicrobial efficacy evaluation is comprehensively provided. However, in my opinion the book suffers from drawbacks that detract from its objective and make it difficult to read. It could be reduced considerably in size and still achieve its stated objectives. For example, the chapters on skin microbiology and statistics both contain extensive material that is probably available from other sources and both devote little time to a discussion of these subjects as they relate specifically to the skin and to topical antimicrobials. Also, it is difficult to read some of the material because some of the terminology and equations used are not defined or explained adequately if at all. Finally, several of the chapters, like the one on the specific topical drugs, are uneven in their coverage.
Assessment: This book is unique in the area covered, and it provides useful and interesting material. However, the uneven coverage, extraneous material, and some undefined terminology make it a difficult read.