Toxicology of the Immune System: A Human Approach / Edition 1by Robert Burrell, Dennis K. Flaherty, Leonard J. Sauers
Robert Burrell Dennis K. Flaherty Leonard J. Sauers Toxicology of the Immune System A Human Approach Due to increased awareness of the AIDS crisis as well as concern about environmental chemicals, immunotoxicology has quickly become one of the most important and controversial topics in occupational medicine and toxicology. This insightful reference/text clarifies… See more details below
Robert Burrell Dennis K. Flaherty Leonard J. Sauers Toxicology of the Immune System A Human Approach Due to increased awareness of the AIDS crisis as well as concern about environmental chemicals, immunotoxicology has quickly become one of the most important and controversial topics in occupational medicine and toxicology. This insightful reference/text clarifies the subject by exploring the basic environmental, occupational, and therapeutic agents that can suppress or strengthen the immune system. The authors provide a necessary bridge between immunology and toxicology to explain the various products and processes that may change immune parameters, affect host resistance to infections and tumors, and alter a system’s future reaction to exposure. They assess the damage done not only to the immune system, but also damage by the immune system as a result of altered functioning. Throughout the book, emphasis is placed on the relevance to existing clinical health and possible future adverse effects. Even the more common immunotoxic conditions, such as food and drug intolerance, cigarette smoking, and occupational asthma, are put into perspective, with straightforward information on possible genetic, environmental, and pharmacological risk factors. Detailed sections are included on:
- Organ systems and target cells most often affected
- Types of damage and injury resulting from immunotoxic reactions
- Clinical populations in which immune system damage occurs
- Methods for investigating the etiology of agents and risk assessment
- Relevance of laboratory data to human risk
- Strategies for achieving standard practices to prevent the disparity in results that characterizes many immune system studies
- Regulatory affairs related to immunotoxicology
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- Product dimensions:
- 10.00(w) x 7.00(h) x 0.71(d)
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Table of Contents
Basic Principles of Toxicology.
Effector Mechanisms: Immunopharmacology.
Effector Mechanisms: Expression of Immunity.
Mechanisms of Injury by the Immune System.
Damage to the Immune System.
Intentional Modulation of the Immune Response: Immunopotentiationand Immunosuppression.
Assessment of Secondary Immunodeficiencies in Man andAnimals.
Relevance of Immunotoxicologic Findings to Human ImmuneCompetence.
Agents and Effects of Immunotoxicity.
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