Toxicology of the Immune System: A Human Approach / Edition 1

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Basic environmental, occupational, and therpaeutic agents that can suppress or strengthen the immune system are investigated in this text. Also covered are the products and processes that may change immune parameters, affect host resistance to infection and tumors, and alter a system's future reaction to exposure.
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Editorial Reviews

A selection of topics designed to introduce immunologists to the rapidly growing field of immunotoxicology, focusing on the effect environmental and occupational chemicals have on the immune system, and to familiarize them with the microbiological principles of infection and host resistance. Emphasizes clinical and epidemiological data, rather than laboratory experiments with animals models (as most such studies do), and includes such aspects as food and drug intolerance, cigarette smoking, and occupational asthma. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9780471290698
  • Publisher: Wiley
  • Publication date: 11/15/1992
  • Edition number: 1
  • Pages: 322
  • Product dimensions: 10.00 (w) x 7.00 (h) x 0.71 (d)

Table of Contents

1 Introduction 1
2 Basic Immunology 9
3 Basic Principles of Toxicology 33
4 Effector Mechanisms: Immunopharmacology 49
5 Effector Mechanisms: Expression of Immunity 79
6 Mechanisms of Injury by the Immune System 104
7 Damage to the Immune System 137
8 Intentional Modulation of the Immune Response: Immunopotentiation and Immunosuppression 158
9 Assessment of Secondary Immunodeficiencies in Man and Animals 181
10 Relevance of Immunotoxicologic Findings to Human Immune Competence 214
11 Agents and Effects of Immunotoxicity 235
12 Regulatory Immunotoxicology 293
Index 311
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