Transgenic and Knockout Models of Neuropsychiatric Disorders / Edition 1

Transgenic and Knockout Models of Neuropsychiatric Disorders / Edition 1

by Gene S. Fisch
     
 

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ISBN-10: 1588295079

ISBN-13: 9781588295071

Pub. Date: 03/16/2010

Publisher: Springer-Verlag New York, LLC

Transgenic and Knockout Models of Neuropsychiatric Disorders provides the reader with a clear and comprehensive assessment of how and whether genetic abnormalities produced in transgenic mouse models manifest neuropsychiatric disorders. The text is divided into three sections, with the first serving as an overview, history, and assessment of neuropsychiatric

Overview

Transgenic and Knockout Models of Neuropsychiatric Disorders provides the reader with a clear and comprehensive assessment of how and whether genetic abnormalities produced in transgenic mouse models manifest neuropsychiatric disorders. The text is divided into three sections, with the first serving as an overview, history, and assessment of neuropsychiatric disorders; the second presenting current research on transgenic models of neurocognitive dysfunction; with the third pertaining to the dysfunctions of affect.

Product Details

ISBN-13:
9781588295071
Publisher:
Springer-Verlag New York, LLC
Publication date:
03/16/2010
Series:
Contemporary Clinical Neuroscience Series
Edition description:
2006
Pages:
296
Product dimensions:
6.10(w) x 9.25(h) x 0.24(d)

Table of Contents

Introduction and Overview

Transgenic and Knockout Models of Psychiatric Disorders: Introduction, History, and Assessment
Gene S. Fisch

Transgenic Mouse Models and Human Psychiatric Disease
Jonathan Flint

Transgenic and Knockout Mouse Models: The Problem of Language
Linda J. Hayes and Diana Delgado

If Only They Could Talk: Genetic Mouse Models for Psychiatric Disorders
Trevor Humby and Lawrence Wilkinson

Transgenic and Knockout Models of Neurocognitive Dysfunction

Spinocerebellar Ataxia Type 1: Lessons From Modeling a Movement Disease in Mice
Harry T. Orr

Mouse Models of Hereditary Mental Retardation
Hans Welzl, Patrizia D'Adamo, David P. Wolfer, and Hans-Peter Lipp

How Can Studies of Animals Help to Uncover the Roles of Genes Implicated in Human Speech and Language Disorders?
Simon E. Fisher

Animal Models of Autism: Proposed Behavioral Paradigms and Biological Studies
Thomas Bourgeron, Stéphane Jamain, and Sylvie Granon

Transgenic and Knockout Models of Neuropsychiatric Dysfunction

Genetic Mouse Models of Psychiatric Disorders: Advantages, Limitations, and Challenges
Joseph A. Gogos and Maria Karayiorgou

Animal Models of Psychosis
Stephen I. Deutsch, Katrice Long, Richard B. Rosse, Yousef Tizabi, Ronit Weizman, Judy Eller, and John Mastropaolo

Animal Models of Anxiety: The Ethological Perspective
Robert Gerlai, Robert Blanchard, and Caroline Blanchard

Modeling Human Anxiety and Depression in Mutant Mice
Andrew Holmes and John F. Cryan

Mutant Mouse Models of Bipolar Disorder: Are There Any?
Anneloes Dirks, Lucianne Groenink, and Berend Olivier

Index

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