Transgenics in Endocrinology / Edition 1
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Transgenics in Endocrinology / Edition 1

by Martin Matzuk
     
 

ISBN-10: 0896037649

ISBN-13: 9780896037649

Pub. Date: 06/01/2001

Publisher: Springer-Verlag New York, LLC

respective fields who have used creative approaches to better understa nd the complex processes that are characteristic of hormonal systems. This volume is a comprehensive review of topics in endocrinology, whic h has as its unifying theme the use of powerful transgenic mouse techn ology to better understand the endocrine physiology of living systems. Transgenic

Overview

respective fields who have used creative approaches to better understa nd the complex processes that are characteristic of hormonal systems. This volume is a comprehensive review of topics in endocrinology, whic h has as its unifying theme the use of powerful transgenic mouse techn ology to better understand the endocrine physiology of living systems. Transgenic mouse technology has added tremendously to our understandi ng of hormone function in vivo. This work is a compendium of advances from a comprehensive group of systems in endocrinology whose common th eme is the use of this powerful technology. The reviews contained with in familiarize the reader with the most recent developments and serve as a basis for further discovery with a goal to advance the field of e ndocrinology. Furthermore the described mouse models will help to fost er new strategies for the evaluation and treatment of human disease. T his text will benefit graduate students, reproductive biologists, endo crinologists (both scientists and clinicians), and other scientists th at desire a comprehensive review of the subject material).

Product Details

ISBN-13:
9780896037649
Publisher:
Springer-Verlag New York, LLC
Publication date:
06/01/2001
Series:
Contemporary Endocrinology Series
Edition description:
2001
Pages:
486
Product dimensions:
7.01(w) x 10.00(h) x 0.04(d)

Table of Contents

Germline Genetic Engineering Techniques in Endocrinology
Albert S. Y. Chang, Michael J. Reardon, and Francesco J. DeMayo

The Transgenic Mouse in Studies of Mammalian Sexual Differentiation
Deanne J. Whitworth and Richard R. Behringer

The In Vivo Function of Müllerian-Inhibiting Substance During Mammalian Sexual Development
Yuji Mishina

Control of Ovarian Function
Julia A. Elvin and Martin M. Matzuk

Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression
Emiliana Borrelli, T. Rajendra Kumar, and Paolo Sassone-Corsi

Functional Analysis of the Bcl2 Gene Family in Transgenic Mice
Andrea J. Ross and Grant R. MacGregor

The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis
Peter J. Donovan and Maria P. de Miguel

Gene Knockout Approaches to Steroidogenesis
Tomonobu Hasegawa, Liping Zhao, Kathleen M. Caron, Morag Young, and Keith L. Parker

The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo
John P. Lydon, Selma Soyal, Bert W. O'Malley, Preeti M. Ismail

Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development
Tiffany N. Seagroves and Jeffrey M. Rosen

Prolactin and the Prolactin Receptor
Nelson D. Horseman

Transgenic Models for Oxytocin and Vasopressin
Larry J. Young and Thomas R. Insel

Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function
Ruth A. Keri and John H. Nilson

Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation
Daniel J. Bernard and Teresa K. Woodruff

Transgenic Analysis of the Proopiomelanocortin Neuroendocrine System
Malcolm J. Low, Marcelo Rubinstein, and E. Cheng Chan

Overexpression and Targeted Disruption of Genes Involved inthe Control of Growth, Food Intake, and Obesity
Andrzej Bartke and Michael Michalkiewicz

Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors
Carolyn A. Bondy and Domenico Accili

Use of Transgenic Animals in Skeleton Biology
Thomas Günther, Mary Jo Doherty, and Gerard Karsenty

Transgenic Mouse Models of Prostate Cancer
Robert J. Matusik, Naoya Masumori, Tania Thomas, Thomas Case, Manik Paul, Susan Kasper, and Scott B. Shappell

Neural- and Endocrine-Cell-Specific Immortalization Using Transgenic Approaches
T. Rajendra Kumar

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