Transgenics in Endocrinology / Edition 1

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $1.99
Usually ships in 1-2 business days
(Save 99%)
Other sellers (Hardcover)
  • All (7) from $1.99   
  • New (4) from $62.28   
  • Used (3) from $1.99   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$62.28
Seller since 2014

Feedback rating:

(0)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
Hardcover New in new dust jacket. Brand New US edition, 3-5 days shipping!

Ships from: Sausalito, CA

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$78.75
Seller since 2005

Feedback rating:

(332)

Condition: New
2001 Hardcover New

Ships from: Portland, OR

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$136.14
Seller since 2014

Feedback rating:

(3)

Condition: New
Hardcover New 0896037649 Brand New US Edition Book in Perfect Condition. Fast Shipping with tracking number.

Ships from: Houston, TX

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$212.68
Seller since 2007

Feedback rating:

(23487)

Condition: New
BRAND NEW

Ships from: Avenel, NJ

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
Page 1 of 1
Showing All
Close
Sort by

Overview

A panel of expert clinical and basic investigators summarize the state-of-the-art in the use of transgenic technology in a broad range of endocrinological applications. Up-to-date and comprehensive, Transgenics in Endocrinology reviews the most recent developments in the analysis of endocrine physiology and its pathologies through mouse models, and provides a host of creative approaches to understand better the complex processes that are characteristic of hormonal systems.
Read More Show Less

Editorial Reviews

Doody's Review Service
Reviewer: Roy E. Weiss, MD, PhD (University of Chicago Medical Center)
Description: This book in the Contemporary Endocrinology series contains reviews by experts in the field of the current knowledge on transgenic and knock out animals and what they have taught us about endocrine systems.
Purpose: Development of embryonic stem cells of the mouse opened the door for the use of this animal in understanding hormonal regulation as well as a model for human disease. Although there has been a virtual explosion of research in this area over the last 10 years, there has not been a single book that brings together all the information in the field of endocrinology. While transgenic reviews have been written and made part of a particular subarea of endocrinology, such as thyroid or diabetes or reproduction, there is a worthy objective in bringing all the subareas together in one book. The three editors have done a wonderful job in getting experts in the field to review their respective areas for publication in one book.
Audience: The title may imply this could be a laboratory manual. Actually it is not intended to be a practical "how to" book, but indeed is much more encylopedic and original. The authors of the individual chapters put together the information learned from their different animal models. Basic scientists in endocrinology will find this an important book as it puts together in one book areas that they might not otherwise be able to find summarized so well. Clinical scientists and clinicians will welcome the book for the insights into endocrine mechanisms.
Features: The book is divided into 20 chapters. The first chapter is perhaps the most technical, but it is an extremely well written review on techniques involved in germline genetic engineering with instructive diagrams. Some of the other 19 chapters discuss specific genes, such as Bc12 gene family, prolactin, oxytocine, and vasopressin. Other chapters are more system-oriented, focusing on such topics as control of ovarian function or skeletal biology or obesity. The index is very helpful as a resource to determine if a particular hormone or factor has been discussed in the book. Although it does not detract from the book's usefulness, a section on diabetes is missing.
Assessment: This month another book covering similar topics, Transgenic Models in Endocrinology edited by Maria Castro (Kluwer Academic Publishers, 2001) has appeared. The Castro book is also excellent but less encyclopedic than this one. Although some of the topics are covered in both books, they are presented with a different perspective. Castro has chapters on POMC and CRF which are not in Matzuk et al. On the other hand, Matzuk et al. has chapters on prostate cancer, breast development, and the skeleton that are not in the Castro. While the Matzuk et al. is primarily by authors in Houston, Castro's book has a more international author list. Both books are very good and both are similar in content. If I wanted a broader, more inclusive book, I would choose the Matzuk and if I wanted a book with more of a neuroendocrine slant, I would consider Castro.

3 Stars from Doody
Read More Show Less

Product Details

  • ISBN-13: 9780896037649
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 6/1/2001
  • Series: Contemporary Endocrinology Series
  • Edition description: 2001
  • Edition number: 1
  • Pages: 486
  • Product dimensions: 6.96 (w) x 11.08 (h) x 1.12 (d)

Table of Contents

Preface
Contributors
1 Germline Genetic Engineering Techniques in Endocrinology 1
2 The Transgenic Mouse in Studies of Mammalian Sexual Differentiation 19
3 The In Vivo Function of Mullerian-Inhibiting Substance During Mammalian Sexual Development 41
4 Control of Ovarian Function 61
5 Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression 91
6 Functional Analysis of the Bcl2 Gene Family in Transgenic Mice 115
7 The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis 147
8 Gene Knockout Approaches to Steroidogenesis 165
9 The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo 173
10 Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development 205
11 Prolactin and the Prolactin Receptor 231
12 Transgenic Models for Oxytocin and Vasopressin 245
13 Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function 261
14 Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation 297
15 Transgenic Analysis of the Proopiomelanocortin Neuroendocrine System 319
16 Overexpression and Targeted Disruption of Genes Involved in the Control of Growth, Food Intake, and Obesity 339
17 Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors 371
18 Use of Transgenic Animals in Skeleton Biology 385
19 Transgenic Mouse Models of Prostate Cancer 401
20 Neural- and Endocrine-Cell Specific Immortalization Using Transgenic Approaches 427
Index 469
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)